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Healthy Body and Mind Program to Improve Health Outcomes and Reduce Dementia Risk in People With Osteoarthritis: Protocol for a Feasibility and Acceptability Pilot Randomized Controlled Trial

Healthy Body and Mind Program to Improve Health Outcomes and Reduce Dementia Risk in People With Osteoarthritis: Protocol for a Feasibility and Acceptability Pilot Randomized Controlled Trial

Globally, approximately 55 million people are living with dementia [1]. Osteoarthritis is experienced by approximately 528 million people worldwide [2] and is associated with a 20% to 25% increase in dementia risk [3,4]. The prevalence of osteoarthritis has been reported in almost half of people living with dementia [5,6]. Both dementia and osteoarthritis are associated with increased pain and depression [7-9] and reduced quality of life (Qo L) [8,10].

Claire V Burley, William Yeates, Kelly A McLeod, Matthew D Jones, Nattai Borges, Henry Brodaty, Belinda J Parmenter

JMIR Res Protoc 2025;14:e75816


Dementia Caregivers’ Perspectives on Technology’s Place in Care Practices: Mixed Methods Survey

Dementia Caregivers’ Perspectives on Technology’s Place in Care Practices: Mixed Methods Survey

Caring for individuals with dementia is demanding and requires strong, effective systems that support the safety, well-being, and quality of life of both the person living with dementia (PLWD) and their caregivers. Most caregivers are informal, typically spouses, family members, or friends who take on the role without formal training or financial compensation [1,2].

Julia A Scott, Emma Cepukenas, McKenzie Himes, Kennedy Anderson, Kiren Grewal, An Mai, Sheila Yuter, Patricia Simone

JMIR Form Res 2025;9:e69596


A Coach-Supported mHealth Lifestyle Intervention to Reduce Dementia Risk in Persons With Low Socioeconomic Status or a Migration Background: Qualitative Co-Design Study

A Coach-Supported mHealth Lifestyle Intervention to Reduce Dementia Risk in Persons With Low Socioeconomic Status or a Migration Background: Qualitative Co-Design Study

The global prevalence of dementia is expected to increase due to population aging and growth, with up to 40% of cases linked to modifiable risk factors such as high blood pressure, physical inactivity, unhealthy diet, overweight, and smoking [1].

Anne Roos van der Endt, Josephine E Lindhout, Joshua van Apeldoorn, Richler Amponsah, Rayn Ramkishun, Edanur Sert, Casper Craamer, Edo Richard, Marieke P Hoevenaar-Blom, Eric P Moll van Charante

J Particip Med 2025;17:e76094


Development of a Serious Game App (Digimenz) for Patients With Dementia: Prospective Pilot Study for Usability Testing in Inpatient Treatment and Long-Term Care

Development of a Serious Game App (Digimenz) for Patients With Dementia: Prospective Pilot Study for Usability Testing in Inpatient Treatment and Long-Term Care

The number of people living with dementia has been rising globally from 20.2 million in 1990 to more than 50 million in 2019 and is estimated to exceed 150 million in 2050 [1,2]. The rising prevalence leads to increasing numbers of patients with dementia who receive inpatient treatment or live in inpatient care facilities. It is important to provide suitable interventions for these patients.

Sören Freerik Brähmer, Benjamin Iffland, Stefan Kreisel, Martin Driessen, Eva M Trompetter, Meret Schomburg, Max Toepper, Carolin Steuwe

JMIR Serious Games 2025;13:e69812


Home-Based Digital Technologies to Support Aging-in-Place for Rural African American People With Alzheimer Disease and Their Care Partners: Protocol for a Mixed Methods Feasibility Study

Home-Based Digital Technologies to Support Aging-in-Place for Rural African American People With Alzheimer Disease and Their Care Partners: Protocol for a Mixed Methods Feasibility Study

Cognition status will be determined using the 11-item Telephone Interview for Cognitive Status (total score of 40, where lower scores can denote cognitive decline) [51] and the 10-item Quick Dementia Rating System (total score of 30, where higher scores can denote cognitive decline) [52]. The Telephone Interview for Cognitive Status measures a person’s memory, orientation, attention, and language and has been validated for use in multiethnic populations [53].

Otis Owens, Rahul Ghosal, Zachary Beattie, Jeffrey Kaye, JiaJia Zhang, Nora Mattek, Joel Steele, Thomas Riley, Nicole Sharma, Larry Frye, Leonardo Bonilha, Sue Levkoff

JMIR Res Protoc 2025;14:e78623


Applying the Human-Centered Innovation Biodesign Framework to the Development and Piloting of a Program to Mitigate Risk for Cognitive Decline Among Historically Underrepresented Individuals: Case Study

Applying the Human-Centered Innovation Biodesign Framework to the Development and Piloting of a Program to Mitigate Risk for Cognitive Decline Among Historically Underrepresented Individuals: Case Study

Reducing sedentary behavior and physical inactivity has been identified as an important modifiable approach to reduce risk for dementia [1,2]. Physical inactivity is 30% higher for older adults, people with disabilities, including people living with mild cognitive impairment (MCI) and dementia. Additionally, 31% of individuals who identify as Hispanic or Latino do not meet physical activity guidelines [3] and are 1.5 times more likely than non-Hispanic White individuals to develop dementia [4].

Rebecca Lassell, Ada Metaxas, Katherine Wang, Sara Hantgan, Prabhat Gottipati, Sarah Zwerling, Triana Pena, Chava Pollak, Laura Gitlin, Sunit Jariwala

JMIR Form Res 2025;9:e64930


Comparing Caregiver Perceptions of a Social Robot and Tablet for Serious Game Delivery in Dementia Care: Cross-Sectional Comparison Study

Comparing Caregiver Perceptions of a Social Robot and Tablet for Serious Game Delivery in Dementia Care: Cross-Sectional Comparison Study

A total of 120 formal caregivers for individuals living with dementia were recruited from various older adult care institutions. Inclusion criteria were (1) age ≥20 years, (2) currently working as a formal caregiver for persons with dementia, (3) ability to communicate in Mandarin or Taiwanese, and (4) willingness to participate voluntarily with informed consent. Caregivers who provided care for individuals with dementia fewer than 2 days per week were excluded.

Dorothy Bai, Kelvin Tan Cheng Kian, Po-Yin Chen, Yeh-Liang Hsu, Gong-Hong Lin

JMIR Serious Games 2025;13:e76209


Sensorized Motor and Cognitive Dual Task Framework for Dementia Diagnosis: Preliminary Insights From a Cross-Sectional Study

Sensorized Motor and Cognitive Dual Task Framework for Dementia Diagnosis: Preliminary Insights From a Cross-Sectional Study

Therefore, the current approach to dementia, particularly AD, focuses on enhancing early identification and prognosis by identifying robust and trustworthy biomarkers [1]. The scientific community is searching for reliable, affordable, and noninvasive indicators that can be seamlessly integrated into clinical settings. The recent widespread availability of digital devices plays a central role in providing the opportunity to introduce new digital biomarkers [2,3].

Gianmaria Mancioppi, Erika Rovini, Laura Fiorini, Radia Zeghari, Auriane Gros, Valeria Manera, Philippe Robert, Filippo Cavallo

J Med Internet Res 2025;27:e64255


Supporting Individuals With Cognitive Impairment and Family Members in Rural Communities: Protocol for a Mixed Methods Digital Health Study

Supporting Individuals With Cognitive Impairment and Family Members in Rural Communities: Protocol for a Mixed Methods Digital Health Study

Our work is situated within the cognitive decline and impairment stage of the typical disease progression of AD, beginning with preclinical AD (ie, no observable symptoms but potential for changes in the brain), followed by SCD (ie, self-reported difficulty and decline in memory and thinking domains) and MCI (ie, mild impairment in objective performance across multiple domains), and ending in mild, moderate, and severe stages of Dementia due to AD [1].

Eric S Cerino, Megan C McCoy, Margarita Martinez, Thomasina J Seaton, Rasheera Dopson, Travis J Anderson, Gillian Porter, Faith R Shannon, Raechel A Livingston, Amanda D Black, Jacqueline Mogle, Louis Lucero, Michael J McCarthy

JMIR Res Protoc 2025;14:e77958


Professional Support Through a Tailor-Made Mobile App to Reduce Stress and Depressive Symptoms Among Family Caregivers of People With Dementia: Mixed Methods Pilot Study

Professional Support Through a Tailor-Made Mobile App to Reduce Stress and Depressive Symptoms Among Family Caregivers of People With Dementia: Mixed Methods Pilot Study

In 2019, the World Health Organization (WHO) estimated that FCs, on average, provided care and supervision to a person with dementia for 8 hours per day [5]. Most FCs of people with dementia in Sweden are older partners (including spouses and cohabiting partners) and women [6], and a recent study reported that about half of spouses of people with dementia provide care for ≥30 hours per week on average [7].

Aber Sharon Kagwa, Jessica Longhini, Muhammed Nazmul Islam, Sofia Vikström, Åsa Dorell, Hanne Konradsen, Zarina Nahar Kabir

JMIR Form Res 2025;9:e75113