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Conversational Agents Supporting Self-Management in People With a Chronic Disease: Systematic Review

Tessa F Peerbolte, Rozanne JA van Diggelen, Pieter van den Haak, Kim Geurts, Luc JW Evers, Bastiaan R Bloem, Nienke M de Vries, Sanne W van den Berg

J Med Internet Res 2025;27:e72309

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The Effectiveness and Feasibility of Conversational Agents in Supporting Care for Patients With Cancer: Systematic Review and Meta-Analysis

Xiao-han Jiang, Xiu-hong Yuan, Hui Zhao, Jun-sheng Peng

J Med Internet Res 2025;27:e76968

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Predicting Engagement With Conversational Agents in Mental Health Therapy by Examining the Role of Epistemic Trust, Personality, and Fear of Intimacy: Cross-Sectional Web-Based Survey Study

Fanny Guglielmucci, Daniela Di Basilio

JMIR Hum Factors 2025;12:e70698

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Toward a Smartphone-Based and Conversational Agent–Delivered Just-in-Time Adaptive Holistic Lifestyle Intervention for Older Adults Affected by Cognitive Decline: Two-Week Proof-of-Concept Study

Esther Brill, Rasita Vinay, Marcia Nißen, Priyam Joshi, Stefan Klöppel, Tobias Kowatsch

JMIR Form Res 2025;9:e66885

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Effectiveness of AI-Driven Conversational Agents in Improving Mental Health Among Young People: Systematic Review and Meta-Analysis

Yi Feng, Yaming Hang, Wenzhi Wu, Xiaohang Song, Xiyao Xiao, Fangbai Dong, Zhihong Qiao

J Med Internet Res 2025;27:e69639

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Impact of Conversational and Animation Features of a Mental Health App Virtual Agent on Depressive Symptoms and User Experience Among College Students: Randomized Controlled Trial

Stephanie Six, Elizabeth Schlesener, Victoria Hill, Sabarish V Babu, Kaileigh Byrne

JMIR Ment Health 2025;12:e67381

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Ability of ChatGPT to Replace Doctors in Patient Education: Cross-Sectional Comparative Analysis of Inflammatory Bowel Disease

Zelin Yan, Jingwen Liu, Yihong Fan, Shiyuan Lu, Dingting Xu, Yun Yang, Honggang Wang, Jie Mao, Hou-Chiang Tseng, Tao-Hsing Chang, Yan Chen

J Med Internet Res 2025;27:e62857

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Patient Perspectives on Conversational Artificial Intelligence for Atrial Fibrillation Self-Management: Qualitative Analysis

Ritu Trivedi, Tim Shaw, Brodie Sheahen, Clara K Chow, Liliana Laranjo

J Med Internet Res 2025;27:e64325

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Advancing Clinical Chatbot Validation Using AI-Powered Evaluation With a New 3-Bot Evaluation System: Instrument Validation Study

Seungheon Choo, Suyoung Yoo, Kumiko Endo, Bao Truong, Meong Hi Son

JMIR Nursing 2025;8:e63058

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Exploring the Ethical Challenges of Conversational AI in Mental Health Care: Scoping Review

Mehrdad Rahsepar Meadi, Tomas Sillekens, Suzanne Metselaar, Anton van Balkom, Justin Bernstein, Neeltje Batelaan

JMIR Ment Health 2025;12:e60432

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