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Therefore, to determine the association between frailty and the prognosis of patients with cirrhosis, we did a comprehensive review and meta-analysis on the predictive value of frailty in the prognosis of patients with cirrhosis. This information can help develop targeted management measures for patients with cirrhosis and promote their well-being.
The study protocol was officially registered on the PROSPERO website (No. CRD42024497698).
JMIR Med Inform 2025;13:e60683
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Liver cirrhosis is a major global public health threat; from 1990 to 2017, the global estimate of compensated cirrhosis prevalence increased from 66 million cases to 112 million cases [1], and liver cirrhosis directly causes millions of deaths each year due to liver failure and liver cancer [2,3]. Without timely treatment of chronic liver disease of any cause, individuals are at risk of developing liver cirrhosis [4].
JMIR Res Protoc 2024;13:e56607
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Patient Portal Use and Risk of Readmissions in Decompensated Cirrhosis: Retrospective Study
Patient portals are widespread across institutions and are perhaps the most common telehealth tool available to and used by patients with cirrhosis [8,9], thus lending themselves as a telehealth tool that can be leveraged toward addressing gaps in the clinical care of persons with cirrhosis.
JMIR Form Res 2023;7:e47080
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Cirrhosis is the most potent risk factor for HCC and hence constitutes the major screening group for HCC globally. Cirrhosis can be caused by chronic viral hepatitis (B and C), chronic alcohol abuse, inherited metabolic diseases such as genetic haemochromatosis, or in some cases alpha-1-antitrypsin deficiency. The acquired metabolic disorder, nonalcoholic fatty liver disease (NAFLD), has also emerged as an important risk factor.
JMIR Res Protoc 2023;12:e44264
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Recent estimates indicate that the total annual health care cost of advanced liver disease or cirrhosis is close to US $9.5 billion [3]. Cirrhosis may be accompanied by a host of complications that require a complex, patient-centered treatment plan, including biannual surveillance visits [4,5]. However, patients with cirrhosis are often not diagnosed by their primary care provider or, alternatively, are not referred to specialty care after diagnosis [6].
JMIR Form Res 2021;5(11):e27748
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In a prior single-center study, we evaluated the acceptability and performance of the Patient Buddy app for preventing readmissions in patients with cirrhosis [5].
J Med Internet Res 2021;23(4):e24639
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