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Predictive Value of Frailty on Outcomes of Patients With Cirrhosis: Systematic Review and Meta-Analysis

Predictive Value of Frailty on Outcomes of Patients With Cirrhosis: Systematic Review and Meta-Analysis

Therefore, to determine the association between frailty and the prognosis of patients with cirrhosis, we did a comprehensive review and meta-analysis on the predictive value of frailty in the prognosis of patients with cirrhosis. This information can help develop targeted management measures for patients with cirrhosis and promote their well-being. The study protocol was officially registered on the PROSPERO website (No. CRD42024497698).

Wen-Zhen Tang, Sheng-Rui Zhu, Shu-Tian Mo, Yuan-Xi Xie, Zheng-Ke-Ke Tan, Yan-Juan Teng, Kui Jia

JMIR Med Inform 2025;13:e60683

Impact of an Automated Population-Level Cirrhosis Screening Program Using Common Pathology Tests on Rates of Cirrhosis Diagnosis and Linkage to Specialist Care (CAPRISE): Protocol for a Pilot Prospective Single-Arm Intervention Study

Impact of an Automated Population-Level Cirrhosis Screening Program Using Common Pathology Tests on Rates of Cirrhosis Diagnosis and Linkage to Specialist Care (CAPRISE): Protocol for a Pilot Prospective Single-Arm Intervention Study

Liver cirrhosis is a major global public health threat; from 1990 to 2017, the global estimate of compensated cirrhosis prevalence increased from 66 million cases to 112 million cases [1], and liver cirrhosis directly causes millions of deaths each year due to liver failure and liver cancer [2,3]. Without timely treatment of chronic liver disease of any cause, individuals are at risk of developing liver cirrhosis [4].

Joan Ericka Flores, Christina Trambas, Natasha Jovanovic, Alexander J Thompson, Jessica Howell

JMIR Res Protoc 2024;13:e56607

Patient Portal Use and Risk of Readmissions in Decompensated Cirrhosis: Retrospective Study

Patient Portal Use and Risk of Readmissions in Decompensated Cirrhosis: Retrospective Study

Patient portals are widespread across institutions and are perhaps the most common telehealth tool available to and used by patients with cirrhosis [8,9], thus lending themselves as a telehealth tool that can be leveraged toward addressing gaps in the clinical care of persons with cirrhosis.

Jeremy Louissaint, Jeffrey Gibbs, Abhishek Shenoy, Shirley Cohen-Mekelburg, Anna Lok, Elliot Tapper

JMIR Form Res 2023;7:e47080

The Fatty Liver, Cirrhosis, and Liver Cancer Study (TENDENCY): Protocol for a Multicenter Case-Control Study

The Fatty Liver, Cirrhosis, and Liver Cancer Study (TENDENCY): Protocol for a Multicenter Case-Control Study

Cirrhosis is the most potent risk factor for HCC and hence constitutes the major screening group for HCC globally. Cirrhosis can be caused by chronic viral hepatitis (B and C), chronic alcohol abuse, inherited metabolic diseases such as genetic haemochromatosis, or in some cases alpha-1-antitrypsin deficiency. The acquired metabolic disorder, nonalcoholic fatty liver disease (NAFLD), has also emerged as an important risk factor.

Yaqza Hussain, Ayman Bannaga, Neil Fisher, Ashwin Krishnamoorthy, Peter Kimani, Ahmad Malik, Maria Truslove, Shivam Joshi, Megan Hitchins, Abdullah Abbasi, Christopher Corbett, Matthew Brookes, Harpal Randeva, Nwe Ni Than, Ramesh P Arasaradnam

JMIR Res Protoc 2023;12:e44264

A Web-Based, Population-Based Cirrhosis Identification and Management System for Improving Cirrhosis Care: Qualitative Formative Evaluation

A Web-Based, Population-Based Cirrhosis Identification and Management System for Improving Cirrhosis Care: Qualitative Formative Evaluation

Recent estimates indicate that the total annual health care cost of advanced liver disease or cirrhosis is close to US $9.5 billion [3]. Cirrhosis may be accompanied by a host of complications that require a complex, patient-centered treatment plan, including biannual surveillance visits [4,5]. However, patients with cirrhosis are often not diagnosed by their primary care provider or, alternatively, are not referred to specialty care after diagnosis [6].

Sarah J Javier, Justina Wu, Donna L Smith, Fasiha Kanwal, Lindsey A Martin, Jack Clark, Amanda M Midboe

JMIR Form Res 2021;5(11):e27748