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Development of a GPT-4–Powered Virtual Simulated Patient and Communication Training Platform for Medical Students to Practice Discussing Abnormal Mammogram Results With Patients: Multiphase Study

Development of a GPT-4–Powered Virtual Simulated Patient and Communication Training Platform for Medical Students to Practice Discussing Abnormal Mammogram Results With Patients: Multiphase Study

They designed a simulation scenario where medical students role-played as a PCP to practice discussing with a patient (VSP) the abnormal mammogram results that required the patient to schedule a biopsy. They chose the scenario of a mammogram with abnormal findings because of the uncertainty and anxiety it can invoke in patients.

Dan Weisman, Alanna Sugarman, Yue Ming Huang, Lillian Gelberg, Patricia A Ganz, Warren Scott Comulada

JMIR Form Res 2025;9:e65670

Quality of Life in Patients and Their Spouses and Cohabitating Partners in the Year Following a Cancer Biopsy (the Couples Cope Study): Protocol for a Prospective Observational Study

Quality of Life in Patients and Their Spouses and Cohabitating Partners in the Year Following a Cancer Biopsy (the Couples Cope Study): Protocol for a Prospective Observational Study

Using a prospective observational study design and quantitative approaches that model actor-partner effects, we will examine predictors and trajectories of Qo L, individual well-being, and relationship quality and functioning among couples who undergo a cancer biopsy. Patients and their spouses or partners will be recruited prior to a breast or prostate biopsy and complete follow-up assessments for 9 months after the biopsy.

Patricia I Moreno, Sarah M Worch, Jessica L Thomas, Rebecca L Nguyen, Heidy N Medina, Frank J Penedo, Judith T Moskowitz, Betina Yanez, Sheetal M Kircher, Shilajit D Kundu, Sarah C Flury, Elaine O Cheung

JMIR Res Protoc 2024;13:e52361

A New Option for Pain Prevention Using a Therapeutic Virtual Reality Solution for Bone Marrow Biopsy (REVEH Trial): Open-Label, Randomized, Multicenter, Phase 3 Study

A New Option for Pain Prevention Using a Therapeutic Virtual Reality Solution for Bone Marrow Biopsy (REVEH Trial): Open-Label, Randomized, Multicenter, Phase 3 Study

Biopsy was then performed on the posterior iliac crest with a classic trocard (Jamshidi or Monoject bone marrow biopsy needle). In the MEOPA group, administration was started at the same time as the local anesthesia. In the VR group, a 5-minute demonstration session was proposed on the day of randomization to assess tolerance before the biopsy, and the program was started 5 minutes before anesthesia with a maximum duration of 40 minutes.

Katell Le Du, Anne-Lise Septans, Frédéric Maloisel, Hélène Vanquaethem, Anna Schmitt, Marielle Le Goff, Aline Clavert, Marie Zinger, Hugues Bourgeois, Olivier Dupuis, Fabrice Denis, Stéphane Bouchard

J Med Internet Res 2023;25:e38619

Melanoma Identification and Management in an Unsheltered Male Using Teledermatology: Street Medicine Perspective

Melanoma Identification and Management in an Unsheltered Male Using Teledermatology: Street Medicine Perspective

Through this software, physicians could assess photos of the lesion and consider the need for a biopsy. A custom electronic medical record for street medicine use was developed in REDCap. This stored patient data in a confidential manner for team members to review patient charts and coordinate with other providers (Figure 2). Special emphasis is given to social history as it can provide a more complete picture of the patient’s housing status and comorbidities like alcohol use disorder.

Emily Eachus, Taha Rasul, Armen Henderson

JMIR Dermatol 2022;5(4):e42113

Surgical Surprise: Cutaneous Metastasis Presenting for Mohs Micrographic Surgery Without a Prior Diagnostic Biopsy

Surgical Surprise: Cutaneous Metastasis Presenting for Mohs Micrographic Surgery Without a Prior Diagnostic Biopsy

Prior to initiating Mohs surgery, a shave biopsy was performed, revealing a basaloid proliferation with adenomatous differentiation diffusely involving the dermis and subcutis. Given the diagnostic ambiguity regarding this lesion, it was sent for permanent section processing. Evaluation of the permanent section was consistent with metastatic adenocarcinoma.

Spencer Dunaway, Pushkar Aggarwal, Cristin Shaughnessy, Scott Neltner

JMIR Dermatol 2021;4(2):e33241

Evaluating the Diagnostic Accuracy of Reflectance Confocal Microscopy to Diagnose Skin Cancer: Protocol for a Prospective, Multicenter Study

Evaluating the Diagnostic Accuracy of Reflectance Confocal Microscopy to Diagnose Skin Cancer: Protocol for a Prospective, Multicenter Study

In the United Kingdom, 350,000 patients per year are referred to hospitals with suspicious moles, and approximately half undergo a biopsy to identify the 5%-10% who require further treatment [1]. Typically, a dermatologist diagnoses skin cancer based on clinical history and examination that is aided by a dermatoscope. If cancer cannot be ruled out, the lesion is surgically removed or in some cases, it is monitored by repeated visits to the clinic.

Naomi D. Df Herz, Anastasia Chalkidou, Fiona Reid, Stephen F. Keevil, Andrew Coleman, Emma Craythorne, Rakesh Patalay

JMIR Res Protoc 2018;7(8):e170

Confocal Laser Endomicroscopy for the Diagnosis of Urothelial Carcinoma in the Bladder and the Upper Urinary Tract: Protocols for Two Prospective Explorative Studies

Confocal Laser Endomicroscopy for the Diagnosis of Urothelial Carcinoma in the Bladder and the Upper Urinary Tract: Protocols for Two Prospective Explorative Studies

In both studies, patients will undergo in-vivo CLE imaging during surgery, prior to resection or biopsy of suspicious areas for standard histopathologic assessment. The probes are introduced through the working channel of the standard endoscopes. In the bladder, a Karl Storz cystoscope of 22 Fr with 0° optics is used for CLE imaging. Transurethral resection is subsequently performed with a Karl Storz or Olympus resectoscope of 26 Fr.

Esmee IML Liem, Jan Erik Freund, Joyce Baard, D Martijn de Bruin, M Pilar Laguna Pes, C Dilara Savci-Heijink, Ton G van Leeuwen, Theo M de Reijke, Jean JMCH de la Rosette

JMIR Res Protoc 2018;7(2):e34