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Recommendations for Designing a Digital Health Tool for Blindness Prevention Among High-Risk Diabetic Retinopathy Patients: Qualitative Focus Group Study of Adults With Diabetes

Recommendations for Designing a Digital Health Tool for Blindness Prevention Among High-Risk Diabetic Retinopathy Patients: Qualitative Focus Group Study of Adults With Diabetes

Features will inform users of local events, particularly those related to diabetes, offer resources for clinical trials, established programs, and integrate relevant existing applications for managing patient health data. The advisory board showed consensus on the must-have features.

Akua Frimpong, Alvaro Granados, Thomas Chang, Julia Fu, Shannan G Moore, Serina Applebaum, Bolatito Adepoju, Mahima Kaur, Vignesh Hari Krishnan, Amanda Levi, Terika McCall, Kristen Harris Nwanyanwu

JMIR Form Res 2025;9:e65893

Challenges in Implementing Artificial Intelligence in Breast Cancer Screening Programs: Systematic Review and Framework for Safe Adoption

Challenges in Implementing Artificial Intelligence in Breast Cancer Screening Programs: Systematic Review and Framework for Safe Adoption

Although there are over 20 Food and Drug Administration (FDA)–approved AI applications for breast imaging, their adoption and utilization in clinical settings remain highly variable and generally low [6]. Significant barriers to the implementation of AI in breast screening include inconsistent performance, limited generalizability of AI algorithms across diverse scenarios, and a lack of confidence among health care providers.

Serene Goh, Rachel Sze Jen Goh, Bryan Chong, Qin Xiang Ng, Gerald Choon Huat Koh, Kee Yuan Ngiam, Mikael Hartman

J Med Internet Res 2025;27:e62941

Effects of a Computer Vision–Based Exercise Application for People With Knee Osteoarthritis: Randomized Controlled Trial

Effects of a Computer Vision–Based Exercise Application for People With Knee Osteoarthritis: Randomized Controlled Trial

Digital health interventions have the potential to mitigate the time and resource limitations faced by patients with KOA by offering education and self-management through web-based platforms or applications that are scalable, inexpensive, readily available, and high coverage [7-9]. Digital health interventions have been shown to potentially offer benefits in the management of musculoskeletal disorders [10,11].

Dian Zhu, Jianan Zhao, Tong Wu, Beiyao Zhu, Mingxuan Wang, Ting Han

JMIR Mhealth Uhealth 2025;13:e63022

Acoustic and Natural Language Markers for Bipolar Disorder: A Pilot, mHealth Cross-Sectional Study

Acoustic and Natural Language Markers for Bipolar Disorder: A Pilot, mHealth Cross-Sectional Study

Our findings corroborate evidence on the relationships between symptom severity and speech features, supporting the potential predictive role for clinical purposes of digital mental health applications, embedded in a m Health integrated system. First, the speech of participants with BD showed that vocal perturbations (eg, higher instability and hesitations considering voice quality), latency time, and increased silences and pauses over time speaking all correlated to depressive symptoms.

Cristina Crocamo, Riccardo Matteo Cioni, Aurelia Canestro, Christian Nasti, Dario Palpella, Susanna Piacenti, Alessandra Bartoccetti, Martina Re, Valentina Simonetti, Chiara Barattieri di San Pietro, Maria Bulgheroni, Francesco Bartoli, Giuseppe Carrà

JMIR Form Res 2025;9:e65555

Effectiveness of Augmented Reality in the Teaching of Health University Students: Quasi-Experimental Study

Effectiveness of Augmented Reality in the Teaching of Health University Students: Quasi-Experimental Study

The aim was to compare the degree of usability of the two AR applications mentioned above. Moreover, the purpose was to compare the academic performance of the control group and the experimental group of the Universities of Cádiz and Málaga as a result of the use of the AR applications.

Rocío Martín-Valero, Alejandro Vega-Morales Sr, Francisco Javier Martín-Vega, Manuel Rodriguez-Huguet, Maria Carmen Rodríguez-Martínez, Maria Jesus Vinolo-Gil

JMIR Serious Games 2025;13:e54312

Use of Remote Assessment Tools to Substitute Routine Outpatient Care: Scoping Review

Use of Remote Assessment Tools to Substitute Routine Outpatient Care: Scoping Review

The search terms used to describe the intervention were “survey,” “telemedicine,” “mobile applications,” and “tertiary” with synonyms built out from these initial terms. Studies published in the last 10 years in English and indexed in the following databases were searched: Pub Med, CINAHL, Embase, Web of Science, and Cochrane. The Pub Med search strategy is included in Multimedia Appendix 2. Inclusion criteria Study type: Peer-reviewed, full-length studies.

Jayne Barclay, Clair Sullivan, Michael Beckmann, Graeme Mattison, Rebecca Runciman, Elizabeth Martin

J Med Internet Res 2025;27:e65938

Advancing Health Care With Digital Twins: Meta-Review of Applications and Implementation Challenges

Advancing Health Care With Digital Twins: Meta-Review of Applications and Implementation Challenges

These applications correspond to 3 main areas: personalized medicine, operational efficiency and resource management, and advancements in medical research and drug development. DTs have emerged as a transformative tool in health care, offering tailored solutions across various applications. The following sections present 3 critical categories of DT applications, each accompanied by tables outlining the inputs, processes, and outputs relevant to each application.

Mickaël Ringeval, Faustin Armel Etindele Sosso, Martin Cousineau, Guy Paré

J Med Internet Res 2025;27:e69544