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In addition to smartphone-based interventions, encouraging advances have been made in the use of virtual reality (VR) in digital medicine. VR has been implemented in consultations and hospital settings under the supervision of health professionals [36]. Incorporating VR into treatments can alleviate patient symptoms in conditions such as claustrophobia [37,38], post-traumatic stress disorder [39], and smoking cessation [40,41] and may improve adherence to weight loss behaviors [42].
JMIR Mhealth Uhealth 2025;13:e66411
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Deconstructing Participant Behaviors in Virtual Reality Simulation: Ethnographic Analysis
A detailed description of this VR simulation was previously described by Zackoff et al [20]. Participants received a 5-minute orientation to navigation in the VR environment and the functionality of the virtual patient and equipment from a trained VR simulation facilitator. They then received the case description and were instructed to begin their assessment and management of the patient as they would in real life.
JMIR Med Educ 2025;11:e65886
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Design Guidelines for a Game-Based Physical Rehabilitation System: Focus Group Study
Whole-body motion capture VR allows a unique opportunity for individuals to experience a heightened sense of realism during task-specific therapeutic activities. However, clinicians need to be able to match a game’s components to an individual’s functional deficits [59]. Even though none of these games were designed for clinical purposes. The study by Rizzo and Kim [60] stated that “Designers of rehabilitation tasks can benefit from examining the formulas that commercial game developers use.”
JMIR Hum Factors 2025;12:e67336
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Notably, metaverse-based clinics and virtual reality (VR) teletherapy rooms are now being explored as accessible alternatives to traditional clinical settings [5,6].
XR serves as a gateway to the metaverse, encompassing immersive technologies such as VR, augmented reality (AR), and mixed reality (MR). Each of these modalities offers distinct capabilities.
J Med Internet Res 2025;27:e72400
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Since Ivan Sutherland and Bob Sproull created the first virtual reality (VR) headset in 1968, VR technology has evolved significantly [1]. VR involves experiencing digital simulations, ranging from realistic to fantastical, in 3 D spaces using computer technology [2]. Users can experience VR in immersive and nonimmersive forms. Today, VR technology is widely used in gaming, entertainment, education, and therapy.
JMIR Form Res 2025;9:e67765
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Some notable examples of VR-based rehabilitation system that incorporate the VR features are the Amadeo hand rehabilitation device (Tyromotion Gmb H) and the lab custom Tipr device. The Amadeo device is an interactive robotic device for hand function assessment, range of motion exercises, and force control rehabilitation.
JMIR Serious Games 2025;13:e63874
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Evidence strongly supports the notion that VR increases learner motivation and improves the contextualization of the learning experience [17]. In a recent research project of ours, we explored different types of perceived stress encountered during VR-based training in medical emergencies [13].
J Med Internet Res 2025;27:e67412
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Hence, there is still some controversy over whether VR teaching is appropriate in orthopedic education. This paper aims to explore the relationship between VR education and traditional education, as well as their interactive influences. Through meta-analysis and literature review, we will examine the advantages, challenges, and potential of VR education from multiple perspectives.
J Med Internet Res 2025;27:e70266
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Virtual reality (VR) is a relatively new technology that is increasingly used as a distraction tool due to its immersive nature and capacity to engage multiple senses simultaneously [1]. VR utilizes the notion that attention is finite and can be diverted from pain and discomfort and therefore serves as effective cognitive distraction [2]. VR provides immersive engagement, isolating users from the real-world environment and associated pain and anxiety [1].
JMIR Serious Games 2025;13:e66656
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