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Three separate data sets were sampled from the RSC as described previously (Figures S1 and S2 in Multimedia Appendix 1 [21]) and they are (1) derivation data set (n=500,000); (2) validation data set 1 (n=250,000) with the same study start and study end date as the derivation set (synchronous outcome); and (3) validation data set 2 (n=250,000) with 12-month outcome at a different time point to the derivation data set (asynchronous outcome), and 60-month outcome occurring at the same time point as the 12-month
J Med Internet Res 2024;26:e56042
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