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Healthy Body and Mind Program to Improve Health Outcomes and Reduce Dementia Risk in People With Osteoarthritis: Protocol for a Feasibility and Acceptability Pilot Randomized Controlled Trial

Healthy Body and Mind Program to Improve Health Outcomes and Reduce Dementia Risk in People With Osteoarthritis: Protocol for a Feasibility and Acceptability Pilot Randomized Controlled Trial

Osteoarthritis is experienced by approximately 528 million people worldwide [2] and is associated with a 20% to 25% increase in dementia risk [3,4]. The prevalence of osteoarthritis has been reported in almost half of people living with dementia [5,6]. Both dementia and osteoarthritis are associated with increased pain and depression [7-9] and reduced quality of life (Qo L) [8,10].

Claire V Burley, William Yeates, Kelly A McLeod, Matthew D Jones, Nattai Borges, Henry Brodaty, Belinda J Parmenter

JMIR Res Protoc 2025;14:e75816


Impact of a Consumer e-Learning Course on Beliefs, Treatment Choices, and Outcomes Among People With Hip and Knee Osteoarthritis: Qualitative Interview Study

Impact of a Consumer e-Learning Course on Beliefs, Treatment Choices, and Outcomes Among People With Hip and Knee Osteoarthritis: Qualitative Interview Study

Osteoarthritis commonly affects the knee and hip joints, causing persistent pain, impaired function, and reduced quality of life [1]. First-line management, recommended for all people with osteoarthritis, includes lifestyle approaches, such as exercise and weight loss (if overweight) [2-5].

Rachel K Nelligan, Libby Spiers, Rana S Hinman, Kim L Bennell

JMIR Aging 2025;8:e80282


Effect of Lifestyle Modification Through Web-Based Telerehabilitation Monitoring Combined With Supervised Sensorimotor Training After Total Knee Arthroplasty: Randomized Controlled Trial

Effect of Lifestyle Modification Through Web-Based Telerehabilitation Monitoring Combined With Supervised Sensorimotor Training After Total Knee Arthroplasty: Randomized Controlled Trial

Knee osteoarthritis (OA) and low back pain are prevalent rheumatic disorders in Asian regions, posing significant challenges to patients and health care systems [1]. Total Knee Arthroplasty (TKA) is widely recognized as the gold standard management strategy for relieving symptoms associated with degenerative knee arthritis [2]. Rehabilitation following TKA plays a crucial role in improving functional performance and quality of life (QOL) for individuals in this population.

Samreen Sadiq, Rabiya Noor, Rizwan Akram

JMIR Mhealth Uhealth 2025;13:e64643


The Effect and Safety of App-Based Interventions for Populations With Osteoarthritis: Systematic Review and Meta-Analysis of Randomized Controlled Trials

The Effect and Safety of App-Based Interventions for Populations With Osteoarthritis: Systematic Review and Meta-Analysis of Randomized Controlled Trials

Osteoarthritis (OA) is the most common degenerative joint disorder, affecting approximately 528 million people worldwide and affecting one or multiple diarthrodial joints [1,2]. The knee, hip, and hand are the joints most frequently affected by this disease. OA imposes substantial pain and disability on patients, which reduce their quality of life (Qo L) and lead to high economic costs [3-6].

He Zhang, Hongchi Wang, Cheng Zhang, Ruili Zhao, Qian Lv, Luyao Zhang, Haoran Zhang, Shiyan Yan

JMIR Mhealth Uhealth 2025;13:e71193


Efficacy of a Multimodal Ayurveda Regimen in the Management of Primary Knee Osteoarthritis: Protocol for an Open-Label Randomized Controlled Trial

Efficacy of a Multimodal Ayurveda Regimen in the Management of Primary Knee Osteoarthritis: Protocol for an Open-Label Randomized Controlled Trial

Osteoarthritis is a chronic degenerative condition characterized by structural changes in the articular cartilage, ligaments, capsule, synovium, subchondral bone, and periarticular muscles, resulting in joint pain, stiffness, and limited mobility [1]. As per the Osteoarthritis Research Society International, osteoarthritis has all the hallmarks of a serious condition because of associated disability and loss of function [2].

Amit Kumar Rai, Babita Yadav, Uma Kumar, Bharti Gupta, Kishore Patel, Shruti Khanduri, Bhagwan S Sharma, Richa Singhal, Bhogavalli Chandrasekhararao, Narayanam Srikanth, Rabinarayan Acharya

JMIR Res Protoc 2025;14:e68306


Comparing the Quality of Primary Care Electronic Health Record Data in Australia and Canada: Case Study in Osteoarthritis

Comparing the Quality of Primary Care Electronic Health Record Data in Australia and Canada: Case Study in Osteoarthritis

Our research team had previously conducted a data quality assessment of Australian primary care EHR data in the context of osteoarthritis and developed a clinical prediction model for total knee replacement (TKR) surgery from these data [17,21]. Given the similarities in prevalence and management of osteoarthritis in Australia and Canada [22,23], our prediction model may be applicable to Canadian patients with osteoarthritis.

Sharmala Thuraisingam, D Himasara Marasinghe, Kendra Barrick, Fariba Aghajafari, Jo-Anne Manski-Nankervis, Michelle M Dowsey, Hude Quan, Tyler Williamson, Stephanie Garies

J Med Internet Res 2025;27:e69631


Coaching Patients to Understand and Use Patient-Reported Outcome Data: Intervention Design and Evaluation

Coaching Patients to Understand and Use Patient-Reported Outcome Data: Intervention Design and Evaluation

Furthermore, incorporating patient-reported data into a clinical encounter has been shown to improve communication between patients and clinicians [8], which is highly relevant for collaborative conversations and care decisions in chronic conditions including osteoarthritis. The need to refine decision-making in total joint replacement, a common treatment for osteoarthritis, has been specifically acknowledged due to its status as a high-volume elective surgery with known disparities in usage [9-12].

Martha Burla, Brocha Z Stern, Andrew BL Berry, Sarah Pila, Patricia D Franklin

JMIR Form Res 2025;9:e65931


Patients’ Expectations for App-Based Therapy in Knee Osteoarthritis: User-Centered Design Approach

Patients’ Expectations for App-Based Therapy in Knee Osteoarthritis: User-Centered Design Approach

Knee osteoarthritis (KOA) is a prevalent degenerative joint disease affecting 16% of individuals aged 15+ years and 22.9% of those aged 40+ years [1]. As a leading musculoskeletal disorder [2], it poses a growing economic and health burden [3-5], necessitating effective management strategies to mitigate symptoms and improve patient outcomes.

Pika Krištof Mirt, Karmen Erjavec, Sabina Krsnik, Petra Kotnik, Hussein Mohsen

JMIR Rehabil Assist Technol 2025;12:e64607


Effects of a Computer Vision–Based Exercise Application for People With Knee Osteoarthritis: Randomized Controlled Trial

Effects of a Computer Vision–Based Exercise Application for People With Knee Osteoarthritis: Randomized Controlled Trial

Knee osteoarthritis (KOA) is a common and chronic joint disorder that is growing in prevalence as the world’s population ages [1,2]. Exercise has been acknowledged as a nonpharmacological intervention modality for the treatment and prevention of musculoskeletal disorders, including osteoarthritis, osteoporosis, back pain, and rheumatoid arthritis [3].

Dian Zhu, Jianan Zhao, Tong Wu, Beiyao Zhu, Mingxuan Wang, Ting Han

JMIR Mhealth Uhealth 2025;13:e63022


Comparing Artificial Intelligence–Generated and Clinician-Created Personalized Self-Management Guidance for Patients With Knee Osteoarthritis: Blinded Observational Study

Comparing Artificial Intelligence–Generated and Clinician-Created Personalized Self-Management Guidance for Patients With Knee Osteoarthritis: Blinded Observational Study

Knee osteoarthritis (OA) is a prevalent, chronic, degenerative joint disorder that imposes a substantial burden on patients’ quality of life and overall well-being [1]. Epidemiological studies have revealed that knee osteoarthritis affects hundreds of millions of individuals worldwide, with its prevalence increasing with age [2].

Kai Du, Ao Li, Qi-Heng Zuo, Chen-Yu Zhang, Ren Guo, Ping Chen, Wei-Shuai Du, Shu-Ming Li

J Med Internet Res 2025;27:e67830