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For HRQo L, we observed an effect size (Hedges g) of 0.66. As there was some evidence of publication bias toward larger effect sizes and because this meta-analysis also included studies with a waiting list control group, we based our calculations on an effect size of 0.5 (moderate effect). Without correcting for clustering by practice, the sample size based on an unpaired t test, given an effect size of 0.5, adopting power (1−beta) of .8, and alpha .05 2-sided, is 128.
JMIR Res Protoc 2019;8(10):e13738
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To evaluate the outcomes of our automated analysis, we reanalyzed data that were previously analyzed in a manual analysis in a study by Rosmalen et al [18]. This data was obtained from 5 middle-aged (55-59 years old) Caucasian male patients suffering from post-myocardial infarction, recruited from screening for a psychoeducational prevention module (PEP) at the Máxima Medical Center in Eindhoven-Veldhoven, the Netherlands.
JMIR Res Protoc 2015;4(3):e100
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