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Development of a Digital Patient Assistant for the Management of Cyclic Vomiting Syndrome: Patient-Centric Design Study

Development of a Digital Patient Assistant for the Management of Cyclic Vomiting Syndrome: Patient-Centric Design Study

CVS: cyclic vomiting syndrome; DPA: digital patient assistant; ED: emergency department; GI: gastrointestinal. The results from earlier development steps were integrated into the first iteration of the DPA. This prototype was comprised of an introductory bot, a check-in bot, a knowledge hub providing access to CVS-related articles and microlearning videos, and a patient dashboard showing a snapshot of potential triggers, symptoms, episode frequency, DPA use, and correlation with vital health metrics.

Gaurav Narang, Yaozhu J Chen, Nicole Wedel, Melody Wu, Michelle Luo, Ashish Atreja

JMIR Form Res 2024;8:e52251

Fibroblast Activation Protein Overexpression in Gastrointestinal Tumors: Protocol for a Systematic Review and Meta-analysis

Fibroblast Activation Protein Overexpression in Gastrointestinal Tumors: Protocol for a Systematic Review and Meta-analysis

Cancers of the gastrointestinal (GI) tract include colorectal, esophageal, liver, pancreas, and stomach cancer. These 5 major types of GI cancer represented 26% of the global cancer incidence and 35% of all cancer-related deaths in 2018 [1]. A hallmark of GI cancers, especially pancreatic cancer, is the dense stromal tumor microenvironment where cancer-associated fibroblasts (CAFs) represent the major stromal cell type [2].

Yoshiaki Sunami, Ulrich Ronellenfitsch, Jorg Kleeff, Artur Rebelo

JMIR Res Protoc 2023;12:e45176