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Physiologic Response to the Pfizer-BioNTech COVID-19 Vaccine Measured Using Wearable Devices: Prospective Observational Study

Physiologic Response to the Pfizer-BioNTech COVID-19 Vaccine Measured Using Wearable Devices: Prospective Observational Study

A greater amount of sleep in the 7 days prior to receiving the first dose of the vaccine was moderately correlated with a higher percent change in HRV the 2 days following vaccine dose 1 (Pearson R=0.570 day 1; R=0.494 day 2). An array of local and systemic reactions to vaccination were reported by participants, ranging from arm soreness to fatigue and body aches. A greater frequency and duration of symptoms were reported following dose 2 (Figure 4 A, B).

Alexander G Hajduczok, Kara M DiJoseph, Brinnae Bent, Audrey K Thorp, Jon B Mullholand, Stuart A MacKay, Sabrina Barik, Jamie J Coleman, Catharine I Paules, Andrew Tinsley

JMIR Form Res 2021;5(8):e28568