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A Smartphone-Based Self-management Intervention for Individuals With Bipolar Disorder (LiveWell): Empirical and Theoretical Framework, Intervention Design, and Study Protocol for a Randomized Controlled Trial

A Smartphone-Based Self-management Intervention for Individuals With Bipolar Disorder (LiveWell): Empirical and Theoretical Framework, Intervention Design, and Study Protocol for a Randomized Controlled Trial

Using multiple linear regression, a sample size of 200, adjusting for one covariate that explains 20% of the variability in outcome, we have 80% power to detect an increase in R-squared of 3%. Generalized linear mixed models will be used to examine the effects of time, risk strata, and study arm on longitudinal target and determinant data.

Evan H Goulding, Cynthia A Dopke, Rebecca C Rossom, Tania Michaels, Clair R Martin, Chloe Ryan, Geneva Jonathan, Alyssa McBride, Pamela Babington, Mary Bernstein, Andrew Bank, C Spencer Garborg, Jennifer M Dinh, Mark Begale, Mary J Kwasny, David C Mohr

JMIR Res Protoc 2022;11(2):e30710