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Each of the 3 sites were given a separate randomization code, and participants at each site were randomized using a Bayesian Adaptive Design detailed by Brown et al [15]. Subsequent adaptations and adapted randomization schedules were appended to each site within CRIS. The ability of CRIS to ensure accrual equality across study sites was assessed using a Gini coefficient.
JMIR Form Res 2021;5(12):e30368
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