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Ying et al [34] found that collateral puncture therapy can reduce the levels of interleukin-1 β, granulocyte-macrophage colony stimulating factor, tumor necrosis factor α, interleukin-6, and cyclooxygenase-2, while increasing the levels of interleukin-4 and interferon γ. This suggests that collateral puncture therapy enhances the levels of anti-inflammatory cytokines and inhibits the expression of pro-inflammatory cytokines, thereby exerting an anti-inflammatory effect.
JMIR Res Protoc 2025;14:e59682
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The study also found that almost all asymptomatic children had normal laboratory results, consistent with Wang et al’s [35] study in the United States, which found no positive results in extensive screening and electrocardiography tests for asymptomatic children aged 12 years or younger. Therefore, the necessity of these tests in asymptomatic children with accidental drug overdoses remains debatable.
JMIR Pediatr Parent 2025;8:e66951
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Minimum Data Set and Metadata for Active Vaccine Safety Surveillance: Systematic Review
JMIR Public Health Surveill 2025;11:e63161
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In contrast, other studies, such as Li et al [19] and Wang et al [20], observed considerably lower performance, with AUC values of 0.72 and 0.73, respectively. These discrepancies can be attributed to factors such as data quality, sample size, and model architecture. Low-quality datasets, such as retrospective studies or single-center studies, may introduce selection bias and limit the generalizability of models, thereby affecting the reliability of radiomics approaches in clinical practice [21].
J Med Internet Res 2025;27:e71091
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