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Effect of Early Treatment of Spasticity After Stroke on Motor Recovery: Protocol for the Baclotox Multicenter, Double-Blind, Double-Dummy Randomized Controlled Trial

Effect of Early Treatment of Spasticity After Stroke on Motor Recovery: Protocol for the Baclotox Multicenter, Double-Blind, Double-Dummy Randomized Controlled Trial

Because of the different modes of administration of these treatments, each group receives both an injection and oral tablets. The study therefore comprises three arms: (1) a “toxin” group treated with an injection of botulinum toxin and placebo oral baclofen; (2) a “baclofen” group treated with oral baclofen and an injection of placebo botulinum toxin; and (3) a double “placebo” group treated with placebo oral baclofen and an injection of placebo botulinum toxin.

Emmeline Montane, Nabila Brihmat, Camille Cormier, Claire Thalamas, Vanessa Rousseau, Gerard Tap, Xavier De Boissezon, Evelyne Castel-Lacanal, Baclotox Group, Philippe Marque

JMIR Res Protoc 2025;14:e62951

Correction: Patient Experiences With a Mobile Self-Care Solution for Low-Complex Orthopedic Injuries: Mixed Methods Study

Correction: Patient Experiences With a Mobile Self-Care Solution for Low-Complex Orthopedic Injuries: Mixed Methods Study

In “Patient Experiences With a Mobile Self-Care Solution for Low-Complex Orthopedic Injuries: Mixed Methods Study” (JMIR Hum Factors 2025;12:e53074) the authors noted one error. The ninth author’s name previously appeared as: Carel Goslings This has been changed to J Carel Goslings The correction will appear in the online version of the paper on the JMIR Publications website, together with the publication of this correction notice.

Jelle Spierings, Gijs Willinge, Marike Kokke, Sjoerd Repping, Wendela de Lange, Thijs Geerdink, Ruben van Veen, Detlef van der Velde, J Carel Goslings, Bas Twigt, Collaboration Group

JMIR Hum Factors 2025;12:e75812

Telehealth Initiative to Enhance Primary Care Access in Brazil (UBS+Digital Project): Multicenter Prospective Study

Telehealth Initiative to Enhance Primary Care Access in Brazil (UBS+Digital Project): Multicenter Prospective Study

A study conducted in Australia [11] examined health care professionals’ experiences with the rapid upscaling of telehealth during the pandemic. The study found that telephone consultations were the predominant method of telehealth delivery, while video consultations were less frequently used. Although telehealth improved access to care for vulnerable populations and those in rural areas, it posed challenges for patients with language barriers and limited digital literacy.

Celina de Almeida Lamas, Patrícia Gabriela Santana Alves, Luciano Nader de Araújo, Ana Beatriz de Souza Paes, Ana Claudia Cielo, Luciana Maciel de Almeida Lopes, André Longo Araújo de Melo, Thais Yokoyama, Clarice Pagani Savastano, Paula Gobi Scudeller, Carlos Carvalho, Digital Primary Health Unit HCFMUSP Study Group

J Med Internet Res 2025;27:e68434

School-Based Virtual Reality Programming for Obtaining Moderate-Intensity Exercise Among Children With Disabilities: Pre-Post Feasibility Study

School-Based Virtual Reality Programming for Obtaining Moderate-Intensity Exercise Among Children With Disabilities: Pre-Post Feasibility Study

This feasibility study was a community-based participatory research design with 2 phases, namely, a development phase and an implementation phase. The development phase included a 4-month preparation phase, where study staff worked with a community engagement group to modify a working VR randomized controlled trial home-based protocol to a local public high school setting.

Byron Lai, Ashley Wright, Bailey Hutchinson, Larsen Bright, Raven Young, Drew Davis, Sultan Ali Malik, James H Rimmer, Pelham High Community Engagement Group

JMIR Form Res 2025;9:e65801

Assessment of Health System Readiness and Quality of Dementia Services in Peru: Protocol for a Qualitative Study With Stakeholder Interviews and Documentation Review

Assessment of Health System Readiness and Quality of Dementia Services in Peru: Protocol for a Qualitative Study With Stakeholder Interviews and Documentation Review

The 10/66 Dementia Research Group study [25] highlights the high cost of dementia for health systems and the negative mental health impacts on women in LMICs, who are often primary caregivers for people with dementia [26]. This underscores the need for further research on dementia diagnosis and care in LMICs and for directing it effectively toward impactful decision-making.

Maria Lazo-Porras, Francisco Jose Tateishi-Serruto, Christopher Butler, María Sofía Cuba-Fuentes, Daniela Rossini-Vilchez, Silvana Perez-Leon, Miriam Lúcar-Flores, J Jaime Miranda, Antonio Bernabe-Ortiz, Francisco Diez-Canseco, Graham Moore, Filipa Landeiro, Maria Kathia Cardenas, Juan Carlos Vera Tudela, Lee White, Rafael A Calvo, William Whiteley, Jemma Hawkins, IMPACT Salud Study Group

JMIR Res Protoc 2025;14:e60296

Patient Experiences With a Mobile Self-Care Solution for Low-Complex Orthopedic Injuries: Mixed Methods Study

Patient Experiences With a Mobile Self-Care Solution for Low-Complex Orthopedic Injuries: Mixed Methods Study

The aim of this study was therefore to explore the experiences of patients with DD to ensure durable adoption and to improve the protocol. An observational mixed method study was conducted among patients and parents of patients younger than 12 years who sustained low-complex, isolated, stable musculoskeletal injuries parallel to the implementation of DD in 3 Dutch level-2 trauma centers from September 2021 to July 2022 with an inclusion period of 3 months per hospital (Figure 1).

Jelle Spierings, Gijs Willinge, Marike Kokke, Sjoerd Repping, Wendela de Lange, Thijs Geerdink, Ruben van Veen, Detlef van der Velde, Carel Goslings, Bas Twigt, Collaboration Group

JMIR Hum Factors 2025;12:e53074

Understanding the Engagement and Interaction of Superusers and Regular Users in UK Respiratory Online Health Communities: Deep Learning–Based Sentiment Analysis

Understanding the Engagement and Interaction of Superusers and Regular Users in UK Respiratory Online Health Communities: Deep Learning–Based Sentiment Analysis

Regular users’ and superusers’ sentiments when replying to each other: To do this, we first identified threads started by regular users and superusers, denoted as TU and TS, and calculated the AVS of replies written by the other group of users. Specifically, we computed , which denotes the average sentiment of regular users in reply to superusers' initiated threads; and , which denotes the average sentiment of superusers in reply to regular users' initiated threads.

Xiancheng Li, Emanuela Vaghi, Gabriella Pasi, Neil S Coulson, Anna De Simoni, Marco Viviani, AD HOC Group

J Med Internet Res 2025;27:e56038

Identification of Clusters in a Population With Obesity Using Machine Learning: Secondary Analysis of The Maastricht Study

Identification of Clusters in a Population With Obesity Using Machine Learning: Secondary Analysis of The Maastricht Study

Given these promising results and developments in the field of unsupervised ML techniques, we chose to include new developments in this study. In particular, we explore in this paper the clustering of a large multidimensional dataset provided by The Maastricht Study. The Maastricht Study is an observational, prospective, population-based, cohort study [17].

Maik JM Beuken, Melanie Kleynen, Susy Braun, Kees Van Berkel, Carla van der Kallen, Annemarie Koster, Hans Bosma, Tos TJM Berendschot, Alfons JHM Houben, Nicole Dukers-Muijrers, Joop P van den Bergh, Abraham A Kroon, Maastricht Study Management, Iris M Kanera

JMIR Med Inform 2025;13:e64479

Text Messaging Versus Postal Reminders to Improve Participation in a Colorectal Cancer Screening Program: Randomized Controlled Trial

Text Messaging Versus Postal Reminders to Improve Participation in a Colorectal Cancer Screening Program: Randomized Controlled Trial

The trial was stopped early, and we launched a recovery strategy for nonparticipants in the intervention group. The study received ethical approval from the Ethics Committee of the Bellvitge University Hospital (reference PR042/20), which waived the requirement to obtain the participant’s signature as part of the consent process, as the intervention was a minor variation on the invitation practice. The study was performed under Good Clinical Practice and the Declaration of Helsinki.

Nuria Vives, Gemma Binefa, Noemie Travier, Albert Farre, Jon Aritz Panera, Berta Casas, Carmen Vidal, Gemma Ibáñez-Sanz, Montse Garcia, M-TICS research group

JMIR Mhealth Uhealth 2025;13:e64243