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Baclofen is a GABA (γ-aminobutyric acid)-B agonist that reduces spasticity by enhancing presynaptic inhibition, thereby decreasing the excitability of afferents in spinal reflexes. Despite its widespread use and endorsement by the French National Health Authority, Haute Autorité de Santé, as a first-line treatment, studies in animal models have raised concerns about the impact of GABAergic drugs on motor recovery.
JMIR Res Protoc 2025;14:e62951
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Confusion matrices showing the best benchmarks for different classification tasks: (a) binary classification, (b) pressure ulcer (PU) category, and (c) incontinence-associated dermatitis (IAD) category.
To evaluate our model’s performance, we conducted a comparative analysis against the initial hospital inputs recorded in the primary hospital systems, as well as the annotation performance of 2 wound experts and a health care provider without extensive wound expertise on the test dataset.
JMIR AI 2025;4:e67356
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The primary goal of aim 1 is to identify the most effective ATS among the 4 embedded strategies (A+B, A+C, D+E, or D+F, as shown in Table 2) that leads to the greatest reduction in STB. This aim focuses on finding the best-performing ATS rather than testing a hypothesis. The sample size of 480 was found to ensure an 80% probability of correctly identifying the ATS with the lowest mean outcome, assuming that such a strategy exists.
JMIR Res Protoc 2025;14:e68441
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