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To enhance recruitment, a home testing option is provided, allowing families to conveniently perform finger-prick testing and data collection at home.
After screening results are available, a research physician reviews the findings. Participants who test positive for islet autoantibodies are invited to a follow-up visit that includes personalized counseling, targeted educational interventions, and additional metabolic staging to determine their T1 D stage.
JMIR Res Protoc 2025;14:e70575
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Conditional inference trees model the nonlinear relationships between a wide range of predictors and an outcome. As a data mining approach, the conditional inference tree is a data-driven analytic strategy that identifies interacting social determinants from many candidate predictors to determine which predictors are most relevant to specific outcomes.
J Med Internet Res 2025;27:e65452
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For example, medical students completing an online module on a basic science topic may be confident in their ability to learn but struggle to see the value in the material beyond their next examination. Conversely, students completing a virtual examination with a standardized patient may see the value in what they are learning but not feel confident in their ability to succeed.
JMIR Med Educ 2025;11:e64179
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All older adults (aged 65 years and older) with polypharmacy (5 or more active outpatient medications) presenting to an ED in a large academic medical center in the Northeast United States between January 2022 and March 2022 were identified. Due to budgetary constraints and a lack of prior evidence regarding the performance of LLMs in this task to guide a power calculation, we selected a random sample of 100 unique patients for evaluation.
JMIR Aging 2025;8:e69504
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The aim of this study is to develop risk calculators that best predict (1) a mother’s risk of having a neonate with abnormal fetal growth (large for gestational age [LGA] or small for gestational age [SGA]); (2) a mother’s risk of having a serious adverse neonatal outcome; and (3) a mother’s risk of developing new metabolic disease after pregnancy (Figure 1).
JMIR Res Protoc 2025;14:e72542
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Furthermore, this simplifies the prediction task to a single time point, making it more feasible to compare multiple models and augmentation strategies. Patients with a chest radiograph within 48 hours before the first elevated e CART score were included in the study. Available anterior-posterior or posterior-anterior views were included in the study cohort.
JMIR AI 2025;4:e67144
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Transcripts were coded by the first author following a template analysis approach [18] with NVivo software (version 14; Lumivero), using a prespecified codebook. The codebook was created according to a hybrid approach, using a deductive approach to generate high-level codes based on the CFIR Codebook Template [15], and an inductive approach to incorporate themes that arose from the data [19].
JMIR Form Res 2025;9:e67624
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For each outer fold, a model was fitted with the best hyperparameters, and a receiver operating characteristic curve was obtained using the outer testing set. Using the Youden index, we determined a probability cutoff value for binary classification in each outer fold. The final performance metric was calculated as the average of the 5 AUROCs from the outer folds.
JMIR Med Inform 2025;13:e64113
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This computing process is scalable over a large amount of data. Then, the cohorts were analyzed using Pandas (version 1.3.5). Inference and training of the NLP algorithms have been achieved on a V100 graphics processing unit. The code developed to run the experiments is freely available in a Git Hub repository: Aremaki/Bio Medics [53].
JMIR Med Inform 2025;13:e68704
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Perinatal depression, a condition common in pregnant women, is higher among adolescent mothers than older mothers [10,11] occurring during pregnancy and up to one year after childbirth. Untreated perinatal depression is a risk for negative health outcomes for mothers and their infants [12].
JMIR Form Res 2025;9:e42406
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