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Validation and Comparison of Pediatric Appendicitis Scores and Management Strategies (Project SPASMS): Protocol for a Prospective Multicenter Observational Study

Wei Hao Lee, Sharon O'Brien, Elizabeth J Mckinnon, Simon Craig, Stuart Dalziel, Michael Collin, Natalie Phillips, Franz E Babl, Sarah Julia Davidson, Shane George, Shefali Jani, Doris Tham, Viet Tran, Meredith L Borland

JMIR Res Protoc 2025;14:e67941

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Enhancing Quality of Life in Patients With Hypothyroidism Using a Scientific Yoga Module: Randomized Controlled Trial

Savithri Nilkantham, Amit Singh, Vijaya Majumdar, Harini K N, Snigdha Atmakur

J Med Internet Res 2025;27:e54078

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Suicide Risk Screening in Jails: Protocol for a Pilot Study Leveraging the Mental Health Research Network Algorithm and Health Care Data

Erin B Comartin, Grant Victor, Athena Kheibari, Brian K Ahmedani, Bethany Hedden-Clayton, Richard N Jones, Ted R Miller, Jennifer E Johnson, Lauren M Weinstock, Sheryl Kubiak

JMIR Res Protoc 2025;14:e68517

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Exploring Conceptualizations of COVID-19 Risk in Ideologically Distinct Online Communities: A Computational Grounded Theory Analysis

Tiwaladeoluwa B Adekunle, Jeremy Foote, Toluwani E Adekunle, Nathan TeBlunthuis, Laura K Nelson

J Med Internet Res 2025;27:e67968

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Acceptance-Based Pre-Exposure Prophylaxis Intervention (ACTPrEP) to Engage Young Black Men Who Have Sex With Men in the Southern United States: Protocol for a Pilot Randomized Controlled Trial

Trisha Arnold, Kayla K Giorlando, Andrew P Barnett, Brandon A Gaudiano, Cara M Antonaccio, A Rani Elwy, Precious Patrick Edet, Lori M Ward, Laura Whiteley, Sarah Bailey, Brooke G Rogers, Avery Leigland, Jack C Rusley, Larry K Brown

JMIR Res Protoc 2025;14:e65921

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Use, Usability, and Experience Testing of a Digital Health Intervention to Support Chronic Kidney Disease Self-Management: Mixed Methods Study

The MK&M DHI has been evaluated in a multicenter randomized controlled trial (RCT), Self-Management Intervention through Lifestyle Education for Kidney Health (SMILE-K), which demonstrated positive effects, particularly for those with low levels of activation (knowledge, skills, and confidence in managing their own health) and in those who used the program more [10].

Courtney J Lightfoot, Thomas J Wilkinson, Roseanne E Billany, Gurneet K Sohansoha, Noemi Vadaszy, Ella C Ford, Melanie J Davies, Thomas Yates, Alice C Smith, Matthew P M Graham-Brown