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Leveraging Cognitive and Speech Ecological Momentary Assessment in Individuals With Phenylketonuria: Development and Usability Study of Cognitive Fluctuations in a Rare Disease Population

Leveraging Cognitive and Speech Ecological Momentary Assessment in Individuals With Phenylketonuria: Development and Usability Study of Cognitive Fluctuations in a Rare Disease Population

To make sure that we understand if performance was impacted by time of day, we used t tests to compute whether there was a significant difference in performance between morning EMAs (EMAs 1 and 2), evening (EMA 3 and 6), and morning and midday EMAs (EMA 4 and 5). Finally, for baseline tasks, average performance was reported.

Shifali Singh, Lisa Kluen, Katelin Curtis, Raquel Norel, Carla Agurto, Elizabeth Grinspoon, Zoe Hawks, Shawn Christ, Susan Waisbren, Guillermo Cecchi, Laura Germine

JMIR Form Res 2025;9:e63644