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Validation and Comparison of Pediatric Appendicitis Scores and Management Strategies (Project SPASMS): Protocol for a Prospective Multicenter Observational Study

Validation and Comparison of Pediatric Appendicitis Scores and Management Strategies (Project SPASMS): Protocol for a Prospective Multicenter Observational Study

To describe the epidemiology and management of pediatric appendicitis, illustrating: (A) The burden of disease in patients presenting with acute abdominal pain with the suspicion of appendicitis; (B) The incidence and type of surgical procedures undertaken in the management of appendicitis in ANZ (laparoscopic appendectomy, open appendectomy, nonsurgical management with intravenous antibiotics, and delayed appendectomy); (C) The imaging procedures undertaken in patients assessed for possible appendicitis, and

Wei Hao Lee, Sharon O'Brien, Elizabeth J Mckinnon, Simon Craig, Stuart Dalziel, Michael Collin, Natalie Phillips, Franz E Babl, Sarah Julia Davidson, Shane George, Shefali Jani, Doris Tham, Viet Tran, Meredith L Borland

JMIR Res Protoc 2025;14:e67941

Research Dissemination Strategies in Pediatric Emergency Care Using a Professional Twitter (X) Account: A Mixed Methods Developmental Study of a Logic Model Framework

Research Dissemination Strategies in Pediatric Emergency Care Using a Professional Twitter (X) Account: A Mixed Methods Developmental Study of a Logic Model Framework

development (R) Acquisition of external graphics designer (G) Selection of software and metrics (J) Learning to work with existing technologies for scheduling and publishing (AF) Sudden unexpected team member change (U) Outputs Extracting key teaching points from top PECARN articles into tweet (X) Tweet frequency established at the same time each week (3 times per week) (AH) Tweet visual structure: Intentional or strategic polls, emojis, bullet points, and multimedia such as images and videos (AA, AB, AC, C,

Gwendolyn C Hooley, Julia N Magana, Jason M Woods, Shyam Sivasankar, Lauren VonHoltz, Anita R Schmidt, Todd P Chang, Michelle Lin

JMIR Form Res 2025;9:e59481

The Rapid Online Cognitive Assessment for the Detection of Neurocognitive Disorder: Open-Label Study

The Rapid Online Cognitive Assessment for the Detection of Neurocognitive Disorder: Open-Label Study

We first evaluated how Ro CA evaluated patient drawings (Figure 3 A-C). Ro CA classified 97% (44/46) of the cubes correctly, 91% (42/46) of the infinities correctly, and 98% (45/46) of the clocks correctly. We next calculated the accuracy of Ro CA for each drawing individually (Figure 3 D). We compared the accuracy of each drawing to its statistical baseline by bootstrapping, resampling the accuracy, and counting the number of times it fell below the random classifier.

Calvin Howard, Amy Johnson, Joseph Peedicail, Marcus C Ng

J Med Internet Res 2025;27:e66735

Use, Usability, and Experience Testing of a Digital Health Intervention to Support Chronic Kidney Disease Self-Management: Mixed Methods Study

Use, Usability, and Experience Testing of a Digital Health Intervention to Support Chronic Kidney Disease Self-Management: Mixed Methods Study

Self-Management Intervention through Lifestyle Education for Kidney health (SMILE-K) trial intervention group participant characteristics for those assigned to the intervention group and those who activated their My Kidneys & Me (MK&M) account. ae GFR: estimated glomerular filtration rate. b ACR: albumin to creatinine ratio. c Hb A1c: hemoglobin A1c. d CRP: C-reactive protein. e PAM-13: Patient Activation Measure-13.

Courtney J Lightfoot, Thomas J Wilkinson, Roseanne E Billany, Gurneet K Sohansoha, Noemi Vadaszy, Ella C Ford, Melanie J Davies, Thomas Yates, Alice C Smith, Matthew P M Graham-Brown

J Med Internet Res 2025;27:e75845

Improving HIV Prevention Among Heterosexual Men Seeking Sexually Transmitted Infection Services in Malawi: Protocol for a Type I Effectiveness-Implementation Hybrid Randomized Controlled Trial of Systems Navigator–Delivered Integrated Prevention Package (HPTN 112-NJIRA Study)

Improving HIV Prevention Among Heterosexual Men Seeking Sexually Transmitted Infection Services in Malawi: Protocol for a Type I Effectiveness-Implementation Hybrid Randomized Controlled Trial of Systems Navigator–Delivered Integrated Prevention Package (HPTN 112-NJIRA Study)

This would occur in the intervention arm only, but there will not be any syphilis testing done by systems navigators (they only collect urine for N. gonorrhea and C. trachomatis). All participants will complete study staff-administered surveys using validated scales whenever possible, enabling exploration of predictors of Pr EP persistence and informing targeted objectives and strategies to enhance systems navigation and counseling interventions.

Sarah E Rutstein, Laura Limarzi-Klyn, Jane S Chen, Yaw O Agyei, Shahnaz Ahmed, Ian Bell, Myron Cohen, Jessica M Fogel, Vivian Go, Dan Haines, Erica L Hamilton, Irving F Hoffman, Mina C Hosseinipour, Mark A Marzinke, William C Miller, Mathews Mukatipa, Julie Pulerwitz, Hans M L Spiegel, Ting Ye, Mitch Matoga

JMIR Res Protoc 2025;14:e72981