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Previous needs assessments [12-14] have identified the need for virtual self-management interventions incorporating peer support and for standards of technology delivery and guidance for effective virtual communications in a group setting [20,21].
Our aim is to conduct a pilot multicenter randomized controlled trial (RCT) to evaluate the feasibility and preliminary effectiveness of a virtual group-based SMP for adolescents with JIA in comparison to a waitlist control group.
JMIR Res Protoc 2025;14:e69539
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If the study participant is transferred from a nonstudy site to a study site, the data collection form will be completed by the initial treating physician at the study site; if the study participant is transferred from a study site to a second study site, this will ideally be completed by the initial treating physician at the first study site.
JMIR Res Protoc 2025;14:e67941
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Another study found that SM young adults who were raised in highly stigmatizing environments demonstrated a blunted cortisol response to a social stressor [12].
In addition to limited studies linking minority stress processes to individual markers of stress physiology, research has revealed that SMs, compared to heterosexuals, demonstrate different stress physiology patterns. For example, Juster et al [13] showed that SM men had a lower allostatic load (AL) than heterosexual men.
JMIR Res Protoc 2025;14:e73070
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TIPS used a secure or HIPAA (Health Insurance Portability and Accountability Act)–compliant televideo platform for telehealth service delivery but had a telephone option available as a backup if needed.
JMIR Ment Health 2025;12:e72541
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Words that are more opinion-based (eg, scary and amazing) have a higher subjectivity score, whereas words that are fact-based (eg, data and communication) have a lower subjectivity score. The threshold used in our study is a subjectivity score of 0.5. If the score is greater than or equal to 0.5, the post is labeled as “subjective,” otherwise the post is labeled as “objective.”
JMIR Form Res 2025;9:e60859
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They independently grouped similar codes to generate descriptive themes, reached a consensus through discussion, and consulted a third author (VM-V) when necessary. This phase was conducted from a descriptive and inductive stance, aiming to remain close to the participants’ discourses.
J Med Internet Res 2025;27:e71186
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A bipolar electric current with a frequency of 85 Hz and an impulse width of 350 microseconds is used in an interval approach with 6 seconds of EMS stimulation with a direct impulse boost and 4 seconds of rest. During the 6-second stimulation period, low-effort movements are performed in a standing position. The intensity of the EMS will be regulated on the basis of the individual’s reported Rating of Perceived Exertion (RPE) and the Borg Category Ratio Scale (Borg-CR10) [14].
JMIR Res Protoc 2025;14:e68761
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Each visit includes a physical and neurological consultation by pediatric oncologists, a neuromotor assessment by a physiotherapist, and limited blood tests for children exposed to chemotherapy in utero (with consent). Cardiac screening is added in case of anthracycline exposure; and nephrological and audiological assessment, after platinum-based exposure.
JMIR Res Protoc 2025;14:e71612
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The delivery of Power-Up includes a men-only, virtual, group-based model with men as coaches and an NDPP curriculum designed to be attentive to the concerns and needs of men. Virtual DPP is defined as a DPP program delivered remotely as synchronous classes through a videoconferencing platform. The intervention will be delivered virtually to participants recruited through clinical settings and available in English and Spanish.
JMIR Res Protoc 2025;14:e64405
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A final visit will occur at the trial’s end (24 months). Study visits were initiated by a research assessor, that is, a member of the research team who conducted clinical assessments with participants. After that, the DN had a brief follow-up discussion (approximately 5 min) with participants to provide ongoing support and complete data collection.
JMIR Ment Health 2025;12:e70154
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