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A Multicomponent Strategy to Improve HIV Pre-Exposure Prophylaxis in a Southern US Jail: Protocol for a Type 3 Hybrid Implementation-Effectiveness Trial

A Multicomponent Strategy to Improve HIV Pre-Exposure Prophylaxis in a Southern US Jail: Protocol for a Type 3 Hybrid Implementation-Effectiveness Trial

Uptake of Pr EP is increasing among White MSM on the east and west coasts but remains limited in minority groups in the South [10-12] where HIV incidence is the highest [13]. The Pr EP-to-need ratio, defined as the number of Pr EP users divided by new HIV diagnoses [14], is lower in the South than in any other region, particularly among racial and ethnic minorities, further highlighting inequitable access [15].

Ank E Nijhawan, Jana Kholy, Julia L Marcus, Timothy P Hogan, Robin T Higashi, Jacqueline Naeem, Laura Hansen, Brynn Torres, Barry-Lewis Harris, Song Zhang, Douglas Krakower

JMIR Res Protoc 2025;14:e64813