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Sodium Oxybate as a Potential New Treatment for Catatonia in Patients With Depression, Bipolar Disorder, or a Psychotic Disorder: Protocol for a Randomized Controlled Trial

Sodium Oxybate as a Potential New Treatment for Catatonia in Patients With Depression, Bipolar Disorder, or a Psychotic Disorder: Protocol for a Randomized Controlled Trial

First-line laboratory screen: full blood count, C-reactive protein, renal, liver, and thyroid function tests, blood glucose, creatine phosphokinase, and iron measurement, and drug screen of urine. Repeated laboratory screening, as indicated by the treating physician. Tr: trial reduction of lorazepam. T0a: allocated treatment with lorazepam for 4 days. T0b: allocated treatment with sodium oxybate for 4 days after reduction of lorazepam.

Lilian Bot, Josine G van Mill, Laetitia J C A Smarius, Adriaan W Hoogendoorn, Bram W C Storosum, Christiaan H Vinkers, Gabriel E Jacobs, Gert Jan Lammers, Hanna M Heller, Jantine C A Colen-de Koning, Joris J B van der Vlugt, Marloes S Oudijn, Martijn S van Noorden, Pierre M Bet, Rolf Fronczek, Heleen S van der Heijden, Sjors M M Lange, Ysbrand D van der Werf, Eric R van Exel

JMIR Res Protoc 2025;14:e68356

The Added Value of Parents Practicing in Virtual Reality to Illustrate the Use of Innovative Methods in Parent-Child Interaction Therapy: Single-Case Experimental Design

The Added Value of Parents Practicing in Virtual Reality to Illustrate the Use of Innovative Methods in Parent-Child Interaction Therapy: Single-Case Experimental Design

Participants completed weekly measurements during a baseline phase (phase A, a minimum of 4, 5, or 6 measurements), an intervention period (phase B [PCIT] and phase B’ [PCIT with the addition of VR]), and a follow-up phase (phase C with 3 measurements) that took place 6 months posttreatment. Between phases, a more extensive measurement took place as a way to assess pretreatment, posttreatment, and follow-up group differences as well (Figure 1).

Iza C A Scherpbier, Mariëlle E Abrahamse, Samantha Bouwmeester, Robert G Belleman, Arne Popma, Ramón J L Lindauer

JMIR Pediatr Parent 2025;8:e60752

Grab Bar Grasp Location During Bathtub Exit and Sit-to-Stand Transfers: Biomechanical Evaluation

Grab Bar Grasp Location During Bathtub Exit and Sit-to-Stand Transfers: Biomechanical Evaluation

(C) Horizontal grab bar grasp locations during perturbation exits for HH and SH. (D) Vertical and horizontal grab bar grasp locations during STS. (E) Incline grab bar grasp locations during sit-to-stand. HH: high horizontal; LH: low horizontal; SH: standard horizontal; VRT: vertical.

Iris C Levine, Konika Nirmalanathan, Roger E Montgomery, Alison C Novak

JMIR Rehabil Assist Technol 2025;12:e69442

Collection and Analysis of Repeated Speech Samples: Methodological Framework and Example Protocol

Collection and Analysis of Repeated Speech Samples: Methodological Framework and Example Protocol

We did not collect any information in relation to these criteria for ethical reasons and as Article 5(1)(c) of the General Data Protection Regulation stipulates the collection of minimal necessary data [79]. Detailed health information was superfluous to our study aims and of a sensitive personal nature. Upon completion of the recordings, participants were compensated for their time with e-vouchers redeemable in several shops.

Nicholas Cummins, Lauren Louise White, Zahia Rahman, Catriona Lucas, Tian Pan, Ewan Carr, Faith Matcham, Johnny Downs, Richard Dobson, Thomas F Quatieri, Judith Dineley

JMIR Res Protoc 2025;14:e69431

Development of a Cocreated Decision Aid for Patients With Depression—Combining Data-Driven Prediction With Patients’ and Clinicians’ Needs and Perspectives: Mixed Methods Study

Development of a Cocreated Decision Aid for Patients With Depression—Combining Data-Driven Prediction With Patients’ and Clinicians’ Needs and Perspectives: Mixed Methods Study

In cases with more than two measurements, the last score within 365 days was used (see Section C in Multimedia Appendix 1). Prediction modeling was based on validated Dutch OQ-45 cutoff scores to assess a clinically relevant decrease in symptoms between two measurements (reliable change index: a decrease of at least 14 points in total score) [45,47].

Kaying Kan, Frederike Jörg, Klaas J Wardenaar, Frank J Blaauw, Maarten F Brilman, Ellen Visser, Dennis Raven, Dwayne Meijnckens, Erik Buskens, Danielle C Cath, Bennard Doornbos, Robert A Schoevers, Talitha L Feenstra

J Particip Med 2025;17:e67170