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Allowing for 30% attrition, a minimum of 332 participants (166 per arm) were required to detect a between-group effect of d=0.3 with 90% power. As recommended, a correction for 5 multiple comparisons (3 coprimary outcomes [ISI, SOL, and WASO] and 2 secondary outcomes [ISI response and ISI remission]) using a conservative Bonferroni approach yielded an α of .01 [63].
Primary analyses followed intention-to-treat (ITT) principles.
JMIR Ment Health 2025;12:e84323
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80: Comparison of self-reported dietary intakes from the Automated Self-Administered 24-h recall, 4-d
JMIR Res Protoc 2025;14:e71680
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What’s Next for Smart Implants in Health Care?
J Med Internet Res 2025;27:e87975
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They noted it became easier with practice, and they felt more comfortable in their second session despite the time between sessions (3‐71 d). Confidence in using R2 Play was primarily limited by a lack of familiarity with the assessment protocol and level instructions.
On-screen prompts and automation made it particularly easy for clinicians to navigate the interface: “I think the way it is set up… kind of just the next thing is automatic, I think makes sense from a usability standpoint” (C5).
JMIR Rehabil Assist Technol 2025;12:e78486
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