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Types of HPV Vaccine Misinformation Circulating on Twitter (X) That Parents Find Most Concerning: Insights From a Cross-Sectional Survey and Content Analysis

Types of HPV Vaccine Misinformation Circulating on Twitter (X) That Parents Find Most Concerning: Insights From a Cross-Sectional Survey and Content Analysis

The caregivers in the study were primarily mothers (n=198, 75%), 67% (n=199) were non-Hispanic White, and 54% (n=142) had a high school education or less. Their children had an average age of 8.96 (SD 0.98) years, and 49% (n=128) were male and 51% (n=135) female (Table 1). Participant characteristics (N=263). Demographic information from a cross-sectional Internet survey of 263 US caregivers.

Jennifer C Morgan, Sarah Badlis, Katharine J Head, Gregory Zimet, Joseph N Cappella, Melanie L Kornides

J Med Internet Res 2025;27:e54657

Effects of the National Institutes of Health Stroke Scale and Modified Rankin Scale on Predictive Models of 30-Day Nonelective Readmission and Mortality After Ischemic Stroke: Cohort Study

Effects of the National Institutes of Health Stroke Scale and Modified Rankin Scale on Predictive Models of 30-Day Nonelective Readmission and Mortality After Ischemic Stroke: Cohort Study

Of these 5808 hospitalizations, 794 (13.7%) were excluded from the study analysis because the patient died during the index hospitalization (n=198, 3.4%), the hospitalization originated at a non-KPNC facility (n=504, 8.7%), or follow-up data was incomplete (n=92, 1.6%). The final study population included 5014 hospitalizations. The average age of the study population was 71.9 (SD 13.99) years and 49.4% (2477/5014) of patients were male.

Mai N Nguyen-Huynh, Janet Alexander, Zheng Zhu, Melissa Meighan, Gabriel Escobar

JMIR Med Inform 2025;13:e69102

Cognitive Behavioral Immersion for Depression: Protocol for a Three-Arm Randomized Controlled Trial of Peer-Based Coaching in the Metaverse

Cognitive Behavioral Immersion for Depression: Protocol for a Three-Arm Randomized Controlled Trial of Peer-Based Coaching in the Metaverse

Thus, a total sample size of 306 (n=102 in each study arm) will be effective for detecting meaningful differences in outcomes between CBI and the other conditions. This study was funded in September 2023. Recruitment of study participants began in February 2024. As of January 2025, 306 participants have been enrolled. Data collection is expected to be completed by September 2025. Data have not yet been analyzed.

Noah Robinson, Francisco N Ramos, Steven D Hollon, Gloria T Han, Iony D Ezawa

JMIR Res Protoc 2025;14:e65970

SEARCH Study: Text Messages and Automated Phone Reminders for HPV Vaccination in Uganda: Randomized Controlled Trial

SEARCH Study: Text Messages and Automated Phone Reminders for HPV Vaccination in Uganda: Randomized Controlled Trial

Messages included both reminders about the needed dose as well as educational information about the importance of the HPV vaccine and were based on a successful previous study [17], as well as 85 key informant interviews with caregivers (n=30), adolescents (n=30), health care workers (n=11), school (n=10), and government officials (n=4). First, team members identified the key content, timing, and framing for each message based on the interviews.

Sabrina B Kitaka, Joseph Rujumba, Sarah K Zalwango, Betsy Pfeffer, Lubega Kizza, Juliane P Nattimba, Ashley B Stephens, Nicolette Nabukeera-Barungi, Chelsea S Wynn, Juliet N Babirye, John Mukisa, Ezekiel Mupere, Melissa S Stockwell

JMIR Mhealth Uhealth 2025;13:e63527

Characterization and Evaluation of Department of Veterans Affairs Commission on Accreditation of Rehabilitation Facilities–Accredited Interdisciplinary Pain Rehabilitation Programs: Protocol for a Mixed Methods Program Evaluation

Characterization and Evaluation of Department of Veterans Affairs Commission on Accreditation of Rehabilitation Facilities–Accredited Interdisciplinary Pain Rehabilitation Programs: Protocol for a Mixed Methods Program Evaluation

Interdisciplinary Pain Rehabilitation Program (IPRP) characteristics. a IPRP: Interdisciplinary Pain Rehabilitation Program. b Not applicable. c Y or N: yes or no. d FTE: full-time employment. e FY: fiscal year. f PROs: patient-reported outcomes. This evaluation will be promoted to IPRPs using multiple approaches. In October 2023, the study author (CAF) informally presented the project and recruitment process at the monthly VA IPRP Co P call.

Jolie N Haun, Christopher A Fowler, Dustin D French, Megan C McHugh, Jacquelyn N Heuer, Lisa M Ballistrea, Rachel C Benzinger, S Angel Klanchar, Friedhelm Sandbrink, Jennifer L Murphy

JMIR Res Protoc 2025;14:e72091

Sex Differences in the Variability of Physical Activity Measurements Across Multiple Timescales Recorded by a Wearable Device: Observational Retrospective Cohort Study

Sex Differences in the Variability of Physical Activity Measurements Across Multiple Timescales Recorded by a Wearable Device: Observational Retrospective Cohort Study

Using a dataset of minute-level skin temperature data from 600 individuals (male: n=300, 50%; female: n=300, 50%) over 6 months, we developed a tool capable of determining cyclic status, where female individuals’ data that showed an approximately 28-day pattern in nightly maximum temperature were labeled as cyclic, and those without were labeled as acyclic.

Kristin J Varner, Lauryn Keeler Bruce, Severine Soltani, Wendy Hartogensis, Stephan Dilchert, Frederick M Hecht, Anoushka Chowdhary, Leena Pandya, Subhasis Dasgupta, Ilkay Altintas, Amarnath Gupta, Ashley E Mason, Benjamin L Smarr

J Med Internet Res 2025;27:e66231

Effectiveness of a Mobile Phone-Delivered Multiple Health Behavior Change Intervention (LIFE4YOUth) in Adolescents: Randomized Controlled Trial

Effectiveness of a Mobile Phone-Delivered Multiple Health Behavior Change Intervention (LIFE4YOUth) in Adolescents: Randomized Controlled Trial

A total of 1398 students registered interest in the study, of whom 890 consented, 760 completed the baseline questionnaire, and 756 were randomized to either the LIFE4 YOUth intervention (n=377) or to the waiting list control condition (n=379; Figure 2) between September 2020 and June 2023. Groups were comparable at baseline (Table 1).

Anna Seiterö, Pontus Henriksson, Kristin Thomas, Hanna Henriksson, Marie Löf, Marcus Bendtsen, Ulrika Müssener

J Med Internet Res 2025;27:e69425

Development and Systematic Evaluation of a Progressive Web Application for Women With Cardiac Pain: Usability Study

Development and Systematic Evaluation of a Progressive Web Application for Women With Cardiac Pain: Usability Study

At heart (formerly HEARTPA♀N) [29], a self-management progressive web application, was developed for women with CAD using a sequential phased approach recommended by the Medical Research Council (MRC) [30-32]. In phase 1, an integrated mixed methods systematic review was conducted to evaluate the current evidence related to the self-management of cardiac pain and associated symptoms (eg, dyspnea and fatigue) in women [7,29].

Monica Parry, Tony Huang, Hance Clarke, Ann Kristin Bjørnnes, Paula Harvey, Laura Parente, Colleen Norris, Louise Pilote, Jennifer Price, Jennifer N Stinson, Arland O’Hara, Madusha Fernando, Judy Watt-Watson, Nicole Nickerson, Vincenza Spiteri DeBonis, Donna Hart, Christine Faubert

JMIR Hum Factors 2025;12:e57583

Greater Improvements in Vaccination Outcomes Among Black Young Adults With Vaccine-Resistant Attitudes in the United States South Following a Digital Health Intervention: Latent Profile Analysis of a Randomized Control Trial

Greater Improvements in Vaccination Outcomes Among Black Young Adults With Vaccine-Resistant Attitudes in the United States South Following a Digital Health Intervention: Latent Profile Analysis of a Randomized Control Trial

A total of 360 Black young adults were included in this study, of whom 76% (n=272) identified as cisgender or transgender women. The median age was 24 (IQR 21‐27) years, and approximately one-third of participants (n=122) had a bachelor’s degree or higher. Overall vaccine uptake at month 3 was low (n=21) and did not significantly differ between the intervention and control arms (odds ratio [OR] 1.88, 95% CI 0.76 to 4.69).

Noah Mancuso, Jenna Michaels, Erica N Browne, Allysha C Maragh-Bass, Jacob B Stocks, Zachary R Soberano, C Lily Bond, Ibrahim Yigit, Maria Leonora G Comello, Margo Adams Larsen, Kathryn E Muessig, Audrey Pettifor, Lisa B Hightow-Weidman, Henna Budhwani, Marie C D Stoner

JMIR Public Health Surveill 2025;11:e67370