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Evaluating the Effectiveness of a Mobile HIV Prevention App to Increase HIV and Sexually Transmitted Infection Testing and Pre-Exposure Prophylaxis Initiation Among Rural Men Who Have Sex With Men in the Southern United States: Protocol for a Randomized Controlled Trial

Evaluating the Effectiveness of a Mobile HIV Prevention App to Increase HIV and Sexually Transmitted Infection Testing and Pre-Exposure Prophylaxis Initiation Among Rural Men Who Have Sex With Men in the Southern United States: Protocol for a Randomized Controlled Trial

M-Cubed, an adaptation of Health Mindr that provides pop-up HIV prevention messaging, demonstrated efficacy to increase HIV testing and Pr EP uptake among urban MSM [17]. There is a need to understand which components of app-based HIV prevention are necessary to promote prevention to inform future implementation. A standard feature of most app-based HIV prevention interventions is access to free HIV and STI self-test kits [30-32].

Jeb Jones, Georgia Manley, Tiffany R Glynn, Kristin M Wall, Stefan D Baral, E Danny Harris, David Benkeser, Patrick S Sullivan

JMIR Res Protoc 2025;14:e69540