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Coronary Computed Tomographic Angiography to Optimize the Diagnostic Yield of Invasive Angiography for Low-Risk Patients Screened With Artificial Intelligence: Protocol for the CarDIA-AI Randomized Controlled Trial

Coronary Computed Tomographic Angiography to Optimize the Diagnostic Yield of Invasive Angiography for Low-Risk Patients Screened With Artificial Intelligence: Protocol for the CarDIA-AI Randomized Controlled Trial

Two cardiac centers located in Ontario, Canada, will participate in the Car DIA-AI trial: Hamilton Health Sciences’ General Hospital (Hamilton site) and Niagara Health System’s Marotta Family Hospital (Niagara site). These regional referral centers serve a large geographic area in southern Ontario with a population exceeding 1.8 million. ICA referral forms from the region are received at the Heart Investigation Unit located at the Hamilton site.

Jeremy Petch, Juan Pablo Tabja Bortesi, Tej Sheth, Madhu Natarajan, Natalia Pinilla-Echeverri, Shuang Di, Shrikant I Bangdiwala, Karen Mosleh, Omar Ibrahim, Kevin R Bainey, Julian Dobranowski, Maria P Becerra, Katie Sonier, Jon-David Schwalm

JMIR Res Protoc 2025;14:e71726