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Optimizing a Personalized Health Approach for Virtually Treating High-Risk Caregivers of Children With Neurogenetic Conditions (Project WellCAST): Protocol for a Randomized Controlled Trial

Optimizing a Personalized Health Approach for Virtually Treating High-Risk Caregivers of Children With Neurogenetic Conditions (Project WellCAST): Protocol for a Randomized Controlled Trial

It evaluates the severity of symptoms of depression (DASS-D), anxiety (DASS-A), and psychological distress (DASS-S) over the past week. Participants respond on a 4-point Likert scale from 0 (did not apply to me at all) to 3 (applied to me very much, or most of the time). In a sample of parents of children with autism, the total scale as well as all 3 subscales were found to have strong internal consistency (DASS-Total: α=.94, DASS-D: α=.88, DASS-A: α=.83, DASS-S: α=.92) [56].

Bridgette Kelleher, Kaleb Emerson, Lyndsey N Graham, Veronika Vozka, Anne Wheeler, William Fadel, Daniel Foti, Isha Metzger, Mandy Rispoli, Wendy Machalicek, Laurie McLay, Sean Lane, Wei Siong Neo, Allie Carter, Lisa Brown, Jennifer Brown, Laura Lee McIntyre, Elizabeth Salwitz, Gloria Dietz, Riley Naughton, Katlyn Peek, Nicole Hollins, Emma Woodford

JMIR Res Protoc 2025;14:e64360

A Customized Neural Transcranial Magnetic Stimulation Target for Functional Disability Among Veterans With Co-Occurring Alcohol Use Disorder and Mild Traumatic Brain Injury: Protocol for a Pilot Randomized Controlled Trial

A Customized Neural Transcranial Magnetic Stimulation Target for Functional Disability Among Veterans With Co-Occurring Alcohol Use Disorder and Mild Traumatic Brain Injury: Protocol for a Pilot Randomized Controlled Trial

BL: baseline visit; F1: follow-up time point visit occurring 2 weeks after the last active repetitive transcranial magnetic stimulation (r TMS) session; F2: follow-up time point visit occurring 1 month after the last active r TMS session; F3: follow-up time point visit occurring 3 months after the last active r TMS session; F4: follow-up time point visit occurring 6 months after the last active r TMS session; MT: motor threshold visit; PA: post–active r TMS visit; PS: post–sham r TMS visit; S: screening visit.

Amy A Herrold, Alexandra L Aaronson, Dulal Bhaumik, Timothy Durazzo, Sherri L Livengood, Alma Ramic, Patrick Riordan, Neil Jordan, Todd Parrish, Trudy Mallinson, Ibuola O Kale, Andrea Billups, Kelly Krese, Sandra Kletzel, Noah S Philip, Theresa L Bender Pape

JMIR Res Protoc 2025;14:e64909

Improving HIV Prevention Among Heterosexual Men Seeking Sexually Transmitted Infection Services in Malawi: Protocol for a Type I Effectiveness-Implementation Hybrid Randomized Controlled Trial of Systems Navigator–Delivered Integrated Prevention Package (HPTN 112-NJIRA Study)

Improving HIV Prevention Among Heterosexual Men Seeking Sexually Transmitted Infection Services in Malawi: Protocol for a Type I Effectiveness-Implementation Hybrid Randomized Controlled Trial of Systems Navigator–Delivered Integrated Prevention Package (HPTN 112-NJIRA Study)

Literate participants will document their consent by signing the ICF(s). Nonliterate participants will document their informed consent by marking their ICF(s) (eg, with an X, thumbprint, or other mark) in the presence of a literate third-party witness. Participants will be provided with a copy of their ICF if they are willing to receive it. All minors (under the age of 18) will be required to provide assent along with parental consent.

Sarah E Rutstein, Laura Limarzi-Klyn, Jane S Chen, Yaw O Agyei, Shahnaz Ahmed, Ian Bell, Myron Cohen, Jessica M Fogel, Vivian Go, Dan Haines, Erica L Hamilton, Irving F Hoffman, Mina C Hosseinipour, Mark A Marzinke, William C Miller, Mathews Mukatipa, Julie Pulerwitz, Hans M L Spiegel, Ting Ye, Mitch Matoga

JMIR Res Protoc 2025;14:e72981