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Modernizing the Staging of Parkinson Disease Using Digital Health Technology

Modernizing the Staging of Parkinson Disease Using Digital Health Technology

The use of AI and ML techniques such as k-nearest neighbors, random forests, support vector machines, neural networks, and other modeling methods can allow for improved accuracy compared to current staging methods [116,142]. These models may also be readily used to better assess subtype manifestations of the condition at either the prodromal stage or across novel PD phenotypes (similar to ALS, in which both limb and bulbar presentations of the disease occur [52,123]).

John Michael Templeton, Christian Poellabauer, Sandra Schneider, Morteza Rahimi, Taofeek Braimoh, Fhaheem Tadamarry, Jason Margolesky, Shanna Burke, Zeina Al Masry

J Med Internet Res 2025;27:e63105