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Cognitive Behavioral Immersion for Depression: Protocol for a Three-Arm Randomized Controlled Trial of Peer-Based Coaching in the Metaverse

Cognitive Behavioral Immersion for Depression: Protocol for a Three-Arm Randomized Controlled Trial of Peer-Based Coaching in the Metaverse

Power analyses were focused on the ability to detect a medium effect size (Cohen d=0.50) at postcondition in the context of a 2-level random coefficients HLM. Given that the primary contrast of interest would be that between CBI and the other study conditions, calculations were focused on detecting significant differences between two active conditions. Where study parameters in this 2-level model were not yet known, we used standard values and varied parameters to approximate an effective sample size.

Noah Robinson, Francisco N Ramos, Steven D Hollon, Gloria T Han, Iony D Ezawa

JMIR Res Protoc 2025;14:e65970

Characterization and Evaluation of Department of Veterans Affairs Commission on Accreditation of Rehabilitation Facilities–Accredited Interdisciplinary Pain Rehabilitation Programs: Protocol for a Mixed Methods Program Evaluation

Characterization and Evaluation of Department of Veterans Affairs Commission on Accreditation of Rehabilitation Facilities–Accredited Interdisciplinary Pain Rehabilitation Programs: Protocol for a Mixed Methods Program Evaluation

The project protocol was reviewed by the Research and Development Committee of the James A. Haley Veterans’ Hospital (IRBNet 1777324). This project was determined to be nonresearch, and Institutional Review Board approval was not required because the data collection activities were for quality improvement and not for research. Participants only provided consent to be recorded during interviews for data confidentiality purposes.

Jolie N Haun, Christopher A Fowler, Dustin D French, Megan C McHugh, Jacquelyn N Heuer, Lisa M Ballistrea, Rachel C Benzinger, S Angel Klanchar, Friedhelm Sandbrink, Jennifer L Murphy

JMIR Res Protoc 2025;14:e72091