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The Effectiveness of the Be Prepared mHealth App on Recovery of Physical Functioning After Major Elective Surgery: Multicenter Randomized Controlled Trial

The Effectiveness of the Be Prepared mHealth App on Recovery of Physical Functioning After Major Elective Surgery: Multicenter Randomized Controlled Trial

To explore the impact of missing data, the primary outcome, in participants without any follow-up measurement, was once imputed with the lowest score and once with the highest score measured at that time point. To assess possible center effects, we performed a sensitivity analysis, including a 3-way interaction between group allocation, time, and center, which was assessed using a likelihood ratio test [28].

Miriam van der Velde, Marike van der Leeden, Edwin Geleijn, Cindy Veenhof, Karin Valkenet, Be Prepared Group

JMIR Mhealth Uhealth 2025;13:e58703

Mobile Therapeutic Attention for Treatment-Resistant Schizophrenia (m-RESIST) Solution for Improving Clinical and Functional Outcomes in Treatment-Resistant Schizophrenia: Prospective, Multicenter Efficacy Study

Mobile Therapeutic Attention for Treatment-Resistant Schizophrenia (m-RESIST) Solution for Improving Clinical and Functional Outcomes in Treatment-Resistant Schizophrenia: Prospective, Multicenter Efficacy Study

The findings suggest that digital shared decision-making tools may positively impact patient activation, decisional conflict, working alliance, and symptom severity. Specific digital interventions include a tablet app for patients with schizophrenia, designed to assess and record satisfaction with life and treatment domains, facilitating discussions between patients and nurses [45].

Jussi Seppälä, Eva Grasa, Anna Alonso-Solis, Alexandra Roldan-Bejarano, Marianne Haapea, Matti Isohanni, Jouko Miettunen, Johanna Caro Mendivelso, Cari Almazán, Katya Rubinstein, Asaf Caspi, Zolt Unoka, Kinga Farkas, Elisenda Reixach, Jesus Berdun, Judith Usall, Susana Ochoa, Iluminada Corripio, Erika Jääskeläinen, m-Resist Group

JMIR Hum Factors 2025;12:e67659

Effect of Early Treatment of Spasticity After Stroke on Motor Recovery: Protocol for the Baclotox Multicenter, Double-Blind, Double-Dummy Randomized Controlled Trial

Effect of Early Treatment of Spasticity After Stroke on Motor Recovery: Protocol for the Baclotox Multicenter, Double-Blind, Double-Dummy Randomized Controlled Trial

Because of the different modes of administration of these treatments, each group receives both an injection and oral tablets. The study therefore comprises three arms: (1) a “toxin” group treated with an injection of botulinum toxin and placebo oral baclofen; (2) a “baclofen” group treated with oral baclofen and an injection of placebo botulinum toxin; and (3) a double “placebo” group treated with placebo oral baclofen and an injection of placebo botulinum toxin.

Emmeline Montane, Nabila Brihmat, Camille Cormier, Claire Thalamas, Vanessa Rousseau, Gerard Tap, Xavier De Boissezon, Evelyne Castel-Lacanal, Baclotox Group, Philippe Marque

JMIR Res Protoc 2025;14:e62951

Telehealth Initiative to Enhance Primary Care Access in Brazil (UBS+Digital Project): Multicenter Prospective Study

Telehealth Initiative to Enhance Primary Care Access in Brazil (UBS+Digital Project): Multicenter Prospective Study

In order to facilitate this process, an instant group at a messaging app was created for ESF team professionals and local managers to forward their questions. Additionally, synchronous meetings were organized to discuss telehealth experiences from the UBS+Digital project, allowing teams from different PHUs to present their successful cases, meet external speakers, and further engage in collaborative learning.

Celina de Almeida Lamas, Patrícia Gabriela Santana Alves, Luciano Nader de Araújo, Ana Beatriz de Souza Paes, Ana Claudia Cielo, Luciana Maciel de Almeida Lopes, André Longo Araújo de Melo, Thais Yokoyama, Clarice Pagani Savastano, Paula Gobi Scudeller, Carlos Carvalho, Digital Primary Health Unit HCFMUSP Study Group

J Med Internet Res 2025;27:e68434

School-Based Virtual Reality Programming for Obtaining Moderate-Intensity Exercise Among Children With Disabilities: Pre-Post Feasibility Study

School-Based Virtual Reality Programming for Obtaining Moderate-Intensity Exercise Among Children With Disabilities: Pre-Post Feasibility Study

The development phase included a 4-month preparation phase, where study staff worked with a community engagement group to modify a working VR randomized controlled trial home-based protocol to a local public high school setting. The 9-month implementation phase used a “learn-as-you-go” approach with a single group pre- to posttrial design to test the implementation of the developed VR HMD school-based protocol.

Byron Lai, Ashley Wright, Bailey Hutchinson, Larsen Bright, Raven Young, Drew Davis, Sultan Ali Malik, James H Rimmer, Pelham High Community Engagement Group

JMIR Form Res 2025;9:e65801

Assessment of Health System Readiness and Quality of Dementia Services in Peru: Protocol for a Qualitative Study With Stakeholder Interviews and Documentation Review

Assessment of Health System Readiness and Quality of Dementia Services in Peru: Protocol for a Qualitative Study With Stakeholder Interviews and Documentation Review

Dementia shares risk factors with many other common chronic diseases, including health-related behaviors (eg, unhealthy diet, smoking, and physical inactivity), as well as obesity, hypertension, diabetes, depression, and social isolation. Together, these factors account for 35% or more of the population-attributable risk (proportion of new cases of dementia due to the noted exposures).

Maria Lazo-Porras, Francisco Jose Tateishi-Serruto, Christopher Butler, María Sofía Cuba-Fuentes, Daniela Rossini-Vilchez, Silvana Perez-Leon, Miriam Lúcar-Flores, J Jaime Miranda, Antonio Bernabe-Ortiz, Francisco Diez-Canseco, Graham Moore, Filipa Landeiro, Maria Kathia Cardenas, Juan Carlos Vera Tudela, Lee White, Rafael A Calvo, William Whiteley, Jemma Hawkins, IMPACT Salud Study Group

JMIR Res Protoc 2025;14:e60296

Patient Experiences With a Mobile Self-Care Solution for Low-Complex Orthopedic Injuries: Mixed Methods Study

Patient Experiences With a Mobile Self-Care Solution for Low-Complex Orthopedic Injuries: Mixed Methods Study

In addition, it limits unnecessary patient travel to the hospital thereby reducing the environmental impact of health care. Including patients’ perspectives in evaluating new care pathways, whether digitally assisted or not, is crucial for sustainable adoption and quality of care. Clinicians, researchers, and policy makers should prioritize patient involvement throughout the design, prototype, pilot, and evaluation phases.

Jelle Spierings, Gijs Willinge, Marike Kokke, Sjoerd Repping, Wendela de Lange, Thijs Geerdink, Ruben van Veen, Detlef van der Velde, Carel Goslings, Bas Twigt, Collaboration Group

JMIR Hum Factors 2025;12:e53074

Establishing Syndromic Surveillance of Acute Coronary Syndrome, Myocardial Infarction, and Stroke: Registry Study Based on Routine Data From German Emergency Departments

Establishing Syndromic Surveillance of Acute Coronary Syndrome, Myocardial Infarction, and Stroke: Registry Study Based on Routine Data From German Emergency Departments

Yet, Germany currently does not have a surveillance system providing timely information on NCDs, which could especially be important during acute events and situations that impact health at a population level. Evidence suggests, for example, that extreme weather events may lead to an increase in cardiovascular disease and acute myocardial infarction (MI) [5].

Madlen Schranz, Mirjam Rupprecht, Annette Aigner, Leo Benning, Carmen Schlump, Nesrine Charfeddine, Michaela Diercke, Linus Grabenhenrich, Alexander Ullrich, Hannelore Neuhauser, Birga Maier, AKTIN Research Group, Felix Patricius Hans, Sabine Blaschke

JMIR Public Health Surveill 2025;11:e66218

Understanding the Engagement and Interaction of Superusers and Regular Users in UK Respiratory Online Health Communities: Deep Learning–Based Sentiment Analysis

Understanding the Engagement and Interaction of Superusers and Regular Users in UK Respiratory Online Health Communities: Deep Learning–Based Sentiment Analysis

However, the analysis of the network topology alone is not sufficient to fully understand the interactions between regular users and superusers and their impact on the whole community. For this reason, it is necessary to analyze the content of posts and what relationships (if any) exist between the 2 groups with respect to how they react to each other’s content.

Xiancheng Li, Emanuela Vaghi, Gabriella Pasi, Neil S Coulson, Anna De Simoni, Marco Viviani, AD HOC Group

J Med Internet Res 2025;27:e56038