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Brichetto et al [64] found that PROs and clinician-assessed outcomes could be used to build accurate models of MS disease course prediction (ie, transition between a relapsing-remitting form to a secondary progressive form). In addition, PROs and clinician-assessed outcomes, alone or integrated with other indexes such as magnetic resonance imaging outcomes and biomarkers, could help the decision-making process of clinicians in their daily practice.
JMIR Form Res 2024;8:e56074
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In this context, Brichetto et al [70] investigated the effectiveness of balance training based on the Nintendo Wii Balance Board versus a traditional rehabilitative training. Despite the excellent compliance with both interventions, a high clinically significant improvement in balance was shown in the group using the exergame.
JMIR Serious Games 2023;11:e41371
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