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Effect of Early Treatment of Spasticity After Stroke on Motor Recovery: Protocol for the Baclotox Multicenter, Double-Blind, Double-Dummy Randomized Controlled Trial

Effect of Early Treatment of Spasticity After Stroke on Motor Recovery: Protocol for the Baclotox Multicenter, Double-Blind, Double-Dummy Randomized Controlled Trial

Subscores of FMA, specifically FMA-UE and FMA-lower extremity (FMA-LE), from allocation (V0) to the visit 3 months after allocation (V2) are secondary end points. The progression of the FMA score from allocation (V0) to the visit 1 month after allocation (V1) is a secondary end point. Spasticity is assessed using the Tardieu Scale [28]. This scale is of better metrological quality than the Ashworth scale usually used in this type of study [29].

Emmeline Montane, Nabila Brihmat, Camille Cormier, Claire Thalamas, Vanessa Rousseau, Gerard Tap, Xavier De Boissezon, Evelyne Castel-Lacanal, Baclotox Group, Philippe Marque

JMIR Res Protoc 2025;14:e62951

Comparison of Electronic Surveillance With Routine Monitoring for Patients With Lymphoma at High Risk of Relapse: Prospective Randomized Controlled Phase 3 Trial (Sentinel Lymphoma)

Comparison of Electronic Surveillance With Routine Monitoring for Patients With Lymphoma at High Risk of Relapse: Prospective Randomized Controlled Phase 3 Trial (Sentinel Lymphoma)

A total of 53 patients were included between July 12, 2017, and April 7, 2020, from 14 centers in France: Le Mans (16/52, 31%), Besançon (9/52, 17%), Nantes (6/52, 11%), Bordeaux Bergonié (6/52,11%), Bordeaux Nord (6/52, 11%), Mont de Marson (4/52, 8%), Dijon (1/52, 2%), Grenoble (1/52, 2%), Paris (1/52, 2%), Strasbourg (1/52, 2%), and Vannes (1/52, 2%). One patient withdrew consent before randomization, and 27 patients were randomized to the experimental arm and 25 to the control arm.

Katell Le Dû, Adrien Chauchet, Sophie Sadot-Lebouvier, Olivier Fitoussi, Bijou Fontanet, Arnaud Saint-Lezer, Frédéric Maloisel, Cédric Rossi, Sylvain Carras, Anne Parcelier, Magali Balavoine, Anne-Lise Septans

JMIR Cancer 2025;11:e65960