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Authors’ Reply: Is the Pinball Machine a Blind Spot in Serious Games Research?
JMIR Serious Games 2025;13:e73034
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To test the equivalence of groups (ACT and control groups) in participants’ demographic and caregiving-related characteristics, as well as outcome measures in the pretest, the chi-square test (or Fisher exact test when the assumptions for the chi-square were not satisfied) was used for categorical variables, and the 2-sample t test was used for continuous variables. An intent-to-treat approach was used for all outcome analyses (ie, data from all participants were analyzed as randomized).
JMIR Form Res 2025;9:e67545
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Alexander et al [21] found the following 5 patient subtypes: mental health, nontypical AD, typical AD, CVD, and men with cancer. They later identified a consistent subtype with early-onset AD, predominantly female participants, with a faster rate of progression using various machine learning methods [22]. Landi et al [23] used unsupervised deep learning to encode EHRs with temporal information, identifying early-onset AD, later-onset AD with mild comorbidities, and typical-onset AD with moderate symptoms.
JMIR Aging 2025;8:e65178
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