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Sodium Oxybate as a Potential New Treatment for Catatonia in Patients With Depression, Bipolar Disorder, or a Psychotic Disorder: Protocol for a Randomized Controlled Trial

Sodium Oxybate as a Potential New Treatment for Catatonia in Patients With Depression, Bipolar Disorder, or a Psychotic Disorder: Protocol for a Randomized Controlled Trial

In addition, he extensively studied the clinical effects of sodium oxybate, after it was discovered in 1874 by chemist Alexander Zaytsev. The study will be conducted across multiple acute psychiatric wards and medical psychiatric units throughout the Netherlands. Study sites include the following hospitals: Leiden University Medical Centre, Amsterdam University Medical Centre, and Antes-Parnassiagroep, as well as mental health care institutions: GGZ in Geest, Arkin, and GGZ Centraal.

Lilian Bot, Josine G van Mill, Laetitia J C A Smarius, Adriaan W Hoogendoorn, Bram W C Storosum, Christiaan H Vinkers, Gabriel E Jacobs, Gert Jan Lammers, Hanna M Heller, Jantine C A Colen-de Koning, Joris J B van der Vlugt, Marloes S Oudijn, Martijn S van Noorden, Pierre M Bet, Rolf Fronczek, Heleen S van der Heijden, Sjors M M Lange, Ysbrand D van der Werf, Eric R van Exel

JMIR Res Protoc 2025;14:e68356

Evaluating the Effectiveness of a Mobile HIV Prevention App to Increase HIV and Sexually Transmitted Infection Testing and Pre-Exposure Prophylaxis Initiation Among Rural Men Who Have Sex With Men in the Southern United States: Protocol for a Randomized Controlled Trial

Evaluating the Effectiveness of a Mobile HIV Prevention App to Increase HIV and Sexually Transmitted Infection Testing and Pre-Exposure Prophylaxis Initiation Among Rural Men Who Have Sex With Men in the Southern United States: Protocol for a Randomized Controlled Trial

M-Cubed, an adaptation of Health Mindr that provides pop-up HIV prevention messaging, demonstrated efficacy to increase HIV testing and Pr EP uptake among urban MSM [17]. There is a need to understand which components of app-based HIV prevention are necessary to promote prevention to inform future implementation. A standard feature of most app-based HIV prevention interventions is access to free HIV and STI self-test kits [30-32].

Jeb Jones, Georgia Manley, Tiffany R Glynn, Kristin M Wall, Stefan D Baral, E Danny Harris, David Benkeser, Patrick S Sullivan

JMIR Res Protoc 2025;14:e69540