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Development of a Cocreated Decision Aid for Patients With Depression—Combining Data-Driven Prediction With Patients’ and Clinicians’ Needs and Perspectives: Mixed Methods Study

Development of a Cocreated Decision Aid for Patients With Depression—Combining Data-Driven Prediction With Patients’ and Clinicians’ Needs and Perspectives: Mixed Methods Study

In cases with more than two measurements, the last score within 365 days was used (see Section C in Multimedia Appendix 1). Prediction modeling was based on validated Dutch OQ-45 cutoff scores to assess a clinically relevant decrease in symptoms between two measurements (reliable change index: a decrease of at least 14 points in total score) [45,47].

Kaying Kan, Frederike Jörg, Klaas J Wardenaar, Frank J Blaauw, Maarten F Brilman, Ellen Visser, Dennis Raven, Dwayne Meijnckens, Erik Buskens, Danielle C Cath, Bennard Doornbos, Robert A Schoevers, Talitha L Feenstra

J Particip Med 2025;17:e67170

Evaluating the Effectiveness of an Intelligent mHealth Intervention for Child Unintentional Injury Prevention: Protocol for a Cluster Randomized Controlled Trial

Evaluating the Effectiveness of an Intelligent mHealth Intervention for Child Unintentional Injury Prevention: Protocol for a Cluster Randomized Controlled Trial

Eligible streets and towns had a primary health care institution present that (1) provides basic public health services for a population with over 2000 children younger than 5 years of age and (2) reports they are not involved in any active child injury prevention programs.

Yang Yuan, Yuying Jing, Jiyu Li, Jieyi He, David C Schwebel, Peishan Ning, Zhenzhen Rao, Li Li, Guoqing Hu

JMIR Public Health Surveill 2025;11:e76195

A Human-Centered Approach for a Student Mental Health and Well-Being Mobile App: Protocol for Development, Implementation, and Evaluation

A Human-Centered Approach for a Student Mental Health and Well-Being Mobile App: Protocol for Development, Implementation, and Evaluation

A recurrent theme across these sessions was the absence of a personalized, regularly updated medium through which students could effectively engage with available university resources. Although a range of services existed, participants emphasized the need for an integrated system to support continuous search, discovery, and engagement.

Maryam Gholami, David Wing, Manas Satish Bedmutha, Job Godino, Anahi Ibarra, Byron Fergerson, Nicole May, Christopher A Longhurst, Nadir Weibel, Anne Duffy, Heidi Rataj, Karandeep Singh, Kevin Patrick

JMIR Res Protoc 2025;14:e68368

Intervention for Justice-Involved Homeless Veterans With Co-Occurring Substance Use and Mental Health Disorders: Protocol for a Randomized Controlled Hybrid Effectiveness-Implementation Trial

Intervention for Justice-Involved Homeless Veterans With Co-Occurring Substance Use and Mental Health Disorders: Protocol for a Randomized Controlled Hybrid Effectiveness-Implementation Trial

Using a hybrid type 1 effectiveness-implementation design [55], we will test the effectiveness of the MISSION-CJ intervention in a randomized controlled trial (RCT) across 2 large VA health care systems as well as conduct a qualitative evaluation of MISSION-CJ’s implementation.

Kathryn Bruzios, Paige M Shaffer, Daniel M Blonigen, Michael A Cucciare, Michael Andre, Thomas Byrne, Jennifer Smith, David Smelson

JMIR Res Protoc 2025;14:e70750

Natural Language Processing for Identification of Hospitalized People Who Use Drugs: Cohort Study

Natural Language Processing for Identification of Hospitalized People Who Use Drugs: Cohort Study

Some researchers have used the hepatitis C virus (HCV) codes as a marker of drug use, although there are a substantial number of people with HCV who do not currently use drugs or have ever used drugs [16,17]. The barrier to identifying PWUD can potentially be addressed with natural language processing (NLP), to leverage artificial intelligence (AI) algorithms for interpretation of the written text in a context-relevant manner [18].

Taisuke Sato, Emily D Grussing, Ruchi Patel, Jessica Ridgway, Joji Suzuki, Benjamin Sweigart, Robert Miller, Alysse G Wurcel

JMIR AI 2025;4:e63147

Streamlining a Patchwork - Exploring the Challenges of Digital Transformation in Pathology: Ethnographic Study

Streamlining a Patchwork - Exploring the Challenges of Digital Transformation in Pathology: Ethnographic Study

A key analogue practice in pathology that is now being digitized via whole-slide imaging is diagnosis. This means that, instead of examining tissue samples on glass slides under a microscope, the glass slide is scanned as a high-resolution image, and the digital slide is examined on a computer screen. Digitizing this step can be seen as a paradigm shift in the digital transformation of pathology. It affects the entire pathology workflow [6].

Birte Linny Geisler, Ourania Amperidou, Sina Patricia Pauly, Sven Mattern, Christian M Schürch, Claudia Hermann, Christiane Stoffregen, Ilona Steinleitner, Natali Paigin, Claudia Lamß, Falko Fend, Monika A Rieger, Esther Rind, Christine Preiser

J Med Internet Res 2025;27:e63366

Delivering an Electronic Health Record Based Educational Intervention Promoting Peri-Operative Non-Pharmacological Pain Care as Part of a Randomized Controlled Trial: Mixed Method Evaluation of Inpatient Nurses’ Perspectives

Delivering an Electronic Health Record Based Educational Intervention Promoting Peri-Operative Non-Pharmacological Pain Care as Part of a Randomized Controlled Trial: Mixed Method Evaluation of Inpatient Nurses’ Perspectives

These 7 questions were rated on a 10-point numeric rating scale, and participants were provided the anchors, 1=not at all, 10=a great deal. Participants could also select "unable to assess" as a response. Survey items were generated by members of the study team (including nursing professionals, a researcher, and physicians), whose experience helping implement the intervention informed key questions for nursing leadership to assess how implementation was going.

Sarah A Minteer, Cindy Tofthagen, Kathy Sheffield, Susanne Cutshall, Susan Launder, Jane Hein, Mary McGough, Christy M Audeh, Jon C Tilburt, Andrea L Cheville

JMIR Nursing 2025;8:e70332

Impact of the Exposome in Type 1 Diabetes: Protocol for a Scoping Review

Impact of the Exposome in Type 1 Diabetes: Protocol for a Scoping Review

Such a comprehensive understanding is essential for the identification of new strategies for disease prevention and management. Conducting a scoping review is well-suited for this broad research question, as it allows for an exhaustive exploration, particularly for a fragmented research area. Unlike systematic reviews, scoping reviews map existing knowledge, identify research gaps, and comprehensively synthesize the available evidence [27-29].

Maurane Rollet, Gloria A Aguayo, Jean-Pierre Riveline, Emmanuel Cosson, Guy Fagherazzi

JMIR Res Protoc 2025;14:e73424

Exploring the Dilemma of AI Use in Medical Research and Knowledge Synthesis: A Perspective on Deep Research Tools

Exploring the Dilemma of AI Use in Medical Research and Knowledge Synthesis: A Perspective on Deep Research Tools

To mitigate this, we specified a shortlist of essential citations to include, while encouraging the model to explore beyond this predefined set. No further prompt engineering was performed beyond the addition of these citations. These prompts are presented in Table S1, and the accompanying reviews in Table S2a-c of Multimedia Appendix 1. We found that Gemini could deliver a well-structured output but lacked the scientific depth required of a scientific review.

Ariel Yuhan Ong, David A Merle, Siegfried K Wagner, Pearse A Keane

J Med Internet Res 2025;27:e75666