Original Paper
Abstract
Background: Heated tobacco products (HTPs), including I Quit Ordinary Smoking (IQOS), are new tobacco products that use an electronic device to heat compressed tobacco leaves to generate an aerosol for consumers to inhale. Marketing of HTPs is prevalent on Instagram, a popular social media platform.
Objective: This study aims to characterize posts related to HTPs on Instagram and their associations with user engagement.
Methods: Through the Instagram application programming interface, 979 Instagram posts were collected using keywords related to HTPs, such as “IQOS” and “heat-not-burn.” Among them, 596 posts were related to IQOS and other HTP marketing. The codebook was developed from a randomly selected 200 posts on the post content by hand coding, which was applied to the remaining 396 Instagram posts. Summary statistics were calculated, and statistical hypothesis testing was conducted to understand the popularity of Instagram posts on HTPs. Negative binomial regression models were applied to identify Instagram post characteristics associated with user engagement (eg, count).
Results: Among Instagram posts related to HTP marketing (N=596), “product display” was dominant (n=550, 92.28%), followed by “brand promotion” (n=41, 6.88%), and “others” (n=5, 0.84%). Among posts within “product display,” “device only” was the most popular (n=338, 61.45%), followed by “heatstick only” (n=80, 14.55%), “accessory” (n=66, 12%), “device and heatstick” (n=56, 10.18%), and “capsule” (n=10, 1.82%). A univariate negative binomial regression model with pairwise comparisons across “product display” types showed that the number of likes for posts with HTP heatsticks was significantly lower compared to posts with HTP devices, accessories, and device-heatstick sets. Multivariate negative binomial regression models showed that HTP-related Instagram posts with a model or lifestyle elements (;=.60, 95% CI 0.36-0.84) or without obvious product advertising information (=.69, 95% CI 0.49-0.89) received more likes.
Conclusions: It is shown that posts with product displays were dominant among HTP-related posts on Instagram. Posts with model or lifestyle elements are associated with high user engagement, which might be one of the web-based marketing strategies of HTPs.
doi:10.2196/43334
Keywords
Introduction
Heated tobacco product (HTP) is a tobacco product in which, during its consumption, the tobacco leaves are heated to a point that is sufficient to release nicotine vapor without burning. Produced by Philip Morris International (PMI), I Quit Ordinary Smoking (IQOS) is an HTP with a leading market share [
]. Unlike e-cigarettes that use heated liquid, IQOS uses real tobacco leaves that contain toxins and harmful substances [ ]. Globally, there is increasing usage of IQOS. According to PMI’s 2020 third-quarter estimation, the number of total IQOS users increased from 8.8 million to 16.4 million during a 2-year interval [ ]. In Japan, only 0.2% of the population used HTPs in 2015, including IQOS and other products. However, in 2019, the proportion increased to 5.8% for IQOS users only [ ]. After years of regulatory debate, the US Food and Drug Administration (FDA) approved the sale of IQOS in the US market on April 30, 2019 [ ]. Compared to Japan, where IQOS was first launched [ ], the United States is still a growing market for IQOS.On July 7, 2020, the FDA authorized the use of “reduced exposure” (the reduction in the production of harmful and potentially harmful chemicals) for IQOS advertising, which allows IQOS products to be marketed as risk-reduction alternatives to regular tobacco [
]. However, HTPs in general are not risk-free. A previous study showed a similar acute effect of HTPs on cardiovascular health as cigarettes [ ]. A recent study showed that there is a potential positive correlation between HTP exposure, including IQOS, and the risk of adverse respiratory symptoms [ ]. With the FDA’s “reduced exposure” authorization, IQOS has been aggressively marketed and promoted among nonsmokers and young adults [ , ]. The FDA has been closely monitoring IQOS in the tobacco market in the United States to ensure that the marketing is appropriate and prevents youth access and exposure [ ]. Although the import of IQOS has been banned since 2022 due to a patent infringement issue, PMI is fighting to regain the US IQOS market [ ].Social media platforms such as Instagram are now a common platform for the public to share their opinions and are widely used for studying HTPs like IQOS [
, ]. About 71% of the young adults aged between 18 and 29 claimed that they have been Instagram users, which overlaps with the demographic group that IQOS potentially attracts and actual IQOS users [ - ]. A recent investigation on IQOS marketing showed that IQOS has been widely promoted and marketed on Instagram through influential users [ ]. One previous study focusing on characterizing the vaping-related content on Instagram through descriptive analyses has yielded informative outcomes, and the success of this vaping-related study indicates that the descriptive analysis on Instagram is a practical method to gain insights into how tobacco products are discussed or even marketed on social media [ ].In this study, the aim is to explore the status quo of HTP-related posts on Instagram by hand coding HTP-related posts and determine possible associations of Instagram HTP-related posts with user engagement by performing statistical analysis. The results of our study provide valuable insights into how HTP is marketed on Instagram, as well as important factors associated with high user engagement on Instagram, which in turn could provide useful information for FDA regulatory science.
Methods
Data Collection
Instagram posts related to HTPs were collected through Instagram’s application programming interface, using hashtags related to IQOS and HTPs that were previously collected (heated tobacco, heatnotburn, heatstick, heet, iqo, iqos, iqos3duo, iqosfriends, iqosstore, ploom, and tobaccoheatingsystem) [
]. On June 19, 2021, Instagram posts related to HTPs were collected using a breadth-first search. For each hashtag, a maximum of 5000 Instagram posts were collected. The duplicate posts based on the ID that is unique to each post were removed. Finally, 1000 posts were randomly selected from the remaining posts. Duplicate images from different posts were removed using a Python library named ImageHash and confirmed manually, and 979 posts with distinct images were included in this study [ ].Hand Coding
The hand-coding process followed an inductive method that was introduced and adopted by previous literature [
, ]. Initially, 200 Instagram posts were randomly selected to develop the codebook through hand coding. After carefully viewing all 200 randomly selected posts, it was first determined if each post was relevant to HTPs, and then all HTP-related posts were grouped based on their content categories ( ). The first group contains posts that directly show HTP and HTP-related products (headsticks, devices, flavor capsules, and accessories; - [ - ]); the second group contains posts on brand promotion ( [ ]); and the third group contains posts discussing others, such as catch phrases, news, and educational information. In addition, we identified additional content features related to the posts from the first group, “product display,” including model or lifestyle, flavor, product advertisements, and English ( ). Each post can have multiple features. The 200 Instagram posts were hand coded by 2 independent human coders in parallel and achieved an agreement rate of 78% (156/200) with a Kappa statistic of 0.73. The discrepancies were resolved by a group of 4 members, including the 2 original human coders. The remaining 779 Instagram posts were then hand coded by the 2 independent coders using the developed codebook. A Kappa agreement of 0.73 was reached on the remaining posts, and the disagreements were resolved using the same procedure as for the sample posts.Categories and subcategories | Definition | ||
Product display | |||
Accessory | The post shows accessories for HTPa devices, such as HTP cases, stickers, and so on. | ||
Device only | The post shows HTP devices itself. | ||
Heatstick only | The post shows either the heatstick or its packages, typically with an indication of the flavor. | ||
Both device and heatstick | The post shows both the HTP device and the heatstick. | ||
Capsule | The post shows an image of a flavored capsule for HTP. | ||
Brand promotion | |||
Brand promotion | The post does not directly show any HTP products. Instead, it shows elements such as a brand logo, retail stores, and so on. | ||
Others | |||
Catch phrases | The posts in this category have short pieces of text or phrases as the main body of the images. | ||
News | The posts in this category typically show a screenshot of the news articles about HTP. | ||
Educational information | The post serves introductory purposes and typically contains basic facts about HTP. |
aHTP: heated tobacco product.
Features | Definition |
Model or lifestyle | The image includes figures of models or a suggestion of a lifestyle (eg, a pool, a luxurious car). |
Flavor | The image includes information about the flavor of the heated tobacco product. |
Product advertisement | The image includes explicit promotional information (eg, discount details, price). |
English | Whether the post is in English. |
Statistical Analysis
To examine whether there was a popularity difference among the 3 categories (“product display”, “brand promotion”, and “others”), we calculated summary statistics and conducted statistical hypothesis testing such as 2-sample t tests. Similar summary statistics were also applied to the “product display” category to investigate the popularity of different parts of HTPs.
To examine the association of HTP-related Instagram posts with user engagement (the number of likes), the negative binomial regression models were applied in the statistical analysis software R version 4.1.2 (R Core Team). Through pairwise comparisons, the univariate negative binomial regression model was first applied to the “product display” category to examine the difference in the number of likes for the posts with different types of HTPs. The multivariate negative binomial model was then used to identify Instagram post characteristics associated with user engagement, such as product display types and other promotion characteristics including “flavor name mentioned,” “model or lifestyle mentioned,” and so on. Some important account statistics, such as the users’ follower count, the users’ following count, and the total number of media posts by the users, were controlled in our model. The number of followers (the number of Instagram users following this Instagram user), the number of followings (the number of Instagram users that this Instagram user is following), and the number of media (posts) posted by this Instagram user could potentially influence the number of likes of the posts from this user, which should be controlled in the model to eliminate their potential confounding effects.
Ethics Approval
The study has been reviewed and approved by the Office for Human Subject Protection Research Subjects Review Board at the University of Rochester (study ID: STUDY00006570).
Results
Characteristics of Instagram Posts Related to HTPs
Out of 1000 Instagram posts collected using hashtags related to HTPs, we identified 596 Instagram posts related to HTP marketing through hand coding, and 365 of them were IQOS-related. Among all the posts, 550 posts (92.28%) were about “product display,” 41 posts (6.88%) were about “brand promotion,” and the remaining 5 posts (0.84%) were classified as “others” (
). For the “brand promotion” category, approximately half of the posts were about the specific brand IQOS (19/41, 46.34%), and PLOOM-related content made up 12.2% (5/41) of this category. To understand the user engagement of these Instagram posts, we compared the number of likes between different categories. As shown in , the mean number of likes for posts with “product display” (31.30 likes per post) was higher than that for “brand promotion” (17.21 likes per post) and “others” (29.40 likes per post). The median number of likes for “others” (11 likes per post) was slightly higher than that for “product display” (9 likes per post) and “brand promotion” (9 likes per post). Considering the relatively small sample size for the categories “brand promotion” and “others,” it was decided to combine them as 1 category, “not product display.” Our 2-sample t test results showed that the average number of likes for posts in “product display” is significantly higher than that for “not product display” (P=.03).We further divided the 550 “product display” posts into 5 groups based on the product types. Among them, 338 posts (61.45%) were showing “devices only,” 80 posts (14.55%) were showing “heatsticks only,” 66 posts (12%) were showing “accessory,” 56 posts (10.18%) were identified as showing both “devices and heatsticks,” and 10 posts (1.82%) were showing the “capsule” (
). As shown in , the mean number of likes for accessory-related posts was the highest (38.27 likes per post), while that for the “capsule” category was the lowest (9.90 likes per post). For the median of the like count, “accessory” remained the highest (27.25 likes per post), and heatstick-related posts had the lowest value (10.25 likes per post).Category and subcategory | Number of posts, n (%) | Number of likes, mean (SD) | Number of likes, median (IQR) | |
Product display | 550 (92.28) | 31.80 (119.84) | 9 (17) | |
Not product display | ||||
Brand promotion | 41 (6.88) | 17.21 (22.68) | 9 (13) | |
Others | 5 (0.84) | 29.40 (35.97) | 11 (19) | |
Total | 46 (7.72) | 18.54 (24.23) | 9.5 (14.5) |
Product display type | Number of posts, n (%) | Number of likes, mean (SD) | Number of likes, median (IQR) |
Accessory | 66 (12.00) | 38.27 (63.83) | 16.5 (27.25) |
Device only | 338 (61.45) | 35.47 (147.76) | 9 (13) |
Device and heatstick | 56 (10.18) | 29.91 (47.40) | 12.5 (26.5) |
Heatstick only | 80 (14.55) | 14.83 (35.98) | 3.5 (10.25) |
Capsule | 10 (1.82) | 11.50 (9.90) | 9.5 (12.5) |
Instagram Posts Related to HTPs Associated With High User Engagement
As shown by the 95% CI from the negative binomial model in
, the number of likes for posts within “device only” (=.87, 95% CI 0.43-1.31), “accessory” (=.95, 95% CI 0.37-1.53), and “device and heatstick” (=.70, 95% CI 0.09-1.31) display types were significantly higher than that for posts within “heatstick only” display type.Our univariate negative binomial regression model on the association of product display type with the number of likes showed major differences between the “heatstick” category and other categories (
). Thus, the multivariate negative binomial logistic regression model used “heatstick” as the reference category for the product display type variable in the data analysis. As shown in , the differences in the number of likes between the “heatstick” category and other categories were not statistically significant after controlling the other variables in the model (95% CI for the coefficients all covered zero). In addition, the models showed that Instagram posts containing images of models or demonstrating pleasant lifestyles received significantly more likes than the posts without these elements, with =.60 (95% CI 0.36-0.84). The model also showed that posts without obvious advertising information had a significantly higher number of likes than those with ads (=.69, 95% CI 0.49-0.89). Non-English posts received more likes than English posts (=0.24, 95% CI 0.06-0.42). As we expected, having more account followers significantly leads to a higher number of likes (=.57, 95% CI 0.51-0.63).Discussion
Principal Findings
In this study, it is shown that most HTP-related Instagram posts were about “product display.” Among them, posts showing HTP accessories had the highest level of user engagement. Using negative binomial regression models, it is observed that, among the 5 categories of product display, posts showing only the heatstick received significantly fewer likes than the ones showing HTP devices, accessories, or the HTP set containing both the device and heatstick. It also showed that the presence of models, lifestyle, or the absence of advertising information might be contributing factors to the high number of “likes” on HTP-related Instagram posts.
Comparison With Previous Studies
This study showed that the inclusion of model or lifestyle elements could improve user engagement. As reported before, a common strategy for IQOS marketing is to associate the products with elements such as coffee and food [
]. These elements fall into the lifestyle feature using our classification method. In addition, another study stated that sex appeal is an important element in IQOS marketing [ ], which corresponded to the model feature in our study. Therefore, HTP-related Instagram posts, including images of models, attracted more social media users and therefore became a popular marketing strategy.Among HTP-related Instagram posts in our study, posts with product displays were dominant. One previous study on e-cigarettes showed that 81.5% of the provaping posts on Instagram were about product display [
]. Furthermore, the number of provaping posts on Instagram significantly outweighs the number of antivaping posts [ ]. Therefore, similar results from both e-cigarettes and HTPs suggest that “product display” might be one of the most prevalent types of posts for tobacco products on Instagram.The results from negative binomial regression models suggest that posts without advertisement information received more likes, indicating high user engagement. A previous study on the advertisement on social media showed that only 13.02% of users found the advertisement on Instagram informative and useful, a percentage significantly lower when compared to Google (33.53%), Pinterest (29.72%), and Twitter (21.21%) [
]. The low user engagement of Instagram posts with advertisements might result from psychological reactance (an urge to resist the initial intention of the message) [ , ].Limitations
This study has several limitations. In terms of the study methodology, during data collection, the set of hashtags that were used may not have been comprehensive enough to capture all the related posts on Instagram. Therefore, our results may not be representative. Additionally, the data set may include boosted posts, which are paid posts that receive more exposure and are thus more likely to receive more likes. With the data we collected, it is hard to distinguish the boosted posts, which could potentially introduce some bias into the results. Moreover, even though the agreement rate between 2 human coders for hand coding Instagram posts was high, this process might introduce some biases. Lastly, only the posts from a specific time interval were collected. However, HTP-related Instagram posts and the user engagement of these posts might evolve. Therefore, a longitudinal study might be necessary in the future.
In terms of result interpretation, as of February 2021, 71% of adults between 18 and 29 in the United States claimed that they ever used Instagram, while the percentage was only 48% for people between 30 and 49 and 29% for people between 50 and 64 [
]. Therefore, the findings might not represent the whole population. In addition, this collected data revealed disproportionally more “product display” posts than other categories, which may potentially introduce some bias into our results.Conclusions
This study showed the relatively high popularity of HTP-related Instagram posts that display product images. More specifically, the posts containing images of HTP accessories had the highest user engagement level. Considering the underage Instagram users, these Instagram posts with HTPs should be closely monitored and potentially regulated to prevent youth and young adults from using these tobacco products. In addition, it showed that the user engagement level of Instagram posts with the presence of a model or lifestyle, or the lack of advertising elements, was high. These findings could help us design anti-HTP Instagram posts with high user engagement to educate the public about the risk of HTP use in the future. Future studies could take demographic or geographic factors into account to determine how different demographic groups react differently to these HTP-related posts on Instagram.
Acknowledgments
This study was supported by the Western New York Center for Research on Flavored Tobacco Products under cooperative agreement U54CA228110 from the National Cancer Institute of the National Institutes of Health and the US Food and Drug Administration.
Data Availability
The data are available upon reasonable request from the corresponding author.
Authors' Contributions
ZX and DL conceived and designed the study. JC and SX analyzed the data. JC, SX, ZX, and DL wrote the manuscript. JC, SX, ZX, and DL edited the manuscript. All authors edited and approved the final version of the manuscript.
Conflicts of Interest
None declared.
Example image for the “device only” category, reproduced from Marta [
], which is published under Creative Commons Attribution 4.0 International License [ ].PNG File , 197 KB
Example image for the “heatstick only” category, reproduced from Lee [
], which is published under Creative Commons Attribution 4.0 International License [ ].PNG File , 633 KB
Example image for the “device and heatstick” category, reproduced from ACBSA [
], which is published under Creative Commons Attribution 4.0 International License [ ].PNG File , 583 KB
Example image for the “brand promotion” category, reproduced from Tokumeigakarinoaoshima [
], which is published under Creative Commons Attribution 4.0 International License [ ].PNG File , 754 KBReferences
- Heated tobacco products. Tobacco Tactics, University of Bath. 2022. URL: https://tobaccotactics.org/wiki/heated-tobacco-products/ [accessed 2023-01-18]
- IQOS: What you need to know. The University of Texas MD Anderson Cancer Center. 2019. URL: https://www.mdanderson.org/publications/focused-on-health/iqos--what-you-need-to-know.h14-1592991.html [accessed 2023-02-14]
- 2020 third-quarter results. Philip Morris International. 2020. URL: https://www.pmi.com/investor-relations/press-releases-and-events/q3-earnings [accessed 2023-02-08]
- Hori A, Tabuchi T, Kunugita N. Rapid increase in heated tobacco product (HTP) use from 2015 to 2019: from the Japan 'Society and New Tobacco' Internet Survey (JASTIS). Tob Control 2020;30(4):474-475 [FREE Full text] [CrossRef] [Medline]
- FDA permits sale of IQOS tobacco heating system through premarket tobacco product application pathway. US Food and Drug Administration. 2019. URL: https://www.fda.gov/news-events/press-announcements/fda-permits-sale-iqos-tobacco-heating-system-through-premarket-tobacco-product-application-pathway [accessed 2023-02-08]
- Can innovative products like IQOS accelerate the decline of smoking? Philip Morris International. 2020. URL: https://tinyurl.com/2p8hmwxx [accessed 2023-02-08]
- FDA authorizes marketing of IQOS tobacco heating system with 'reduced exposure' information. US Food and Drug Administration. 2020. URL: https://www.fda.gov/news-events/press-announcements/fda-authorizes-marketing-iqos-tobacco-heating-system-reduced-exposure-information [accessed 2023-02-08]
- Fried ND, Gardner JD. Heat-not-burn tobacco products: an emerging threat to cardiovascular health. Am J Physiol Heart Circ Physiol 2020;319(6):H1234-H1239 [FREE Full text] [CrossRef] [Medline]
- Znyk M, Jurewicz J, Kaleta D. Exposure to heated tobacco products and adverse health effects, a systematic review. Int J Environ Res Public Health 2021;18(12):6651 [FREE Full text] [CrossRef] [Medline]
- Henderson KC, Van Do V, Wang Y, Duan Z, Popova L, Spears CA, et al. Brief report on IQOS point-of-sale marketing, promotion and pricing in IQOS retail partner stores in Atlanta, Georgia, USA. Tob Control 2022:1-5 [FREE Full text] [CrossRef] [Medline]
- Mathers A, Schwartz R, O'Connor S, Fung M, Diemert L. Marketing IQOS in a dark market. Tob Control 2019;28(2):237-238. [CrossRef] [Medline]
- Notice of the Commission's final determination finding a violation of Section 337; issuance of a limited exclusion order and cease and desist orders; termination of the investigation. US International Trade Commission. URL: https://www.usitc.gov/secretary/fed_reg_notices/337/337_796_Notice08092013sgl.pdf [accessed 2023-02-14]
- Zou C, Wang X, Xie Z, Li D. Perceptions of the IQOS heated tobacco product on Twitter in the United States. Front Commun 2021 Aug 20;6:163. [CrossRef]
- Gu J, Abroms LC, Broniatowski DA, Evans WD. An investigation of influential users in the promotion and marketing of heated tobacco products on Instagram: a social network analysis. Int J Environ Res Public Health 2022;19(3):1686 [FREE Full text] [CrossRef] [Medline]
- Auxier B, Anderson M. Social media use in 2021. Pew Research Center. 2021. URL: https://www.pewresearch.org/internet/2021/04/07/social-media-use-in-2021/ [accessed 2023-02-08]
- Kim J, Yu H, Lee S, Paek YJ. Awareness, experience and prevalence of heated tobacco product, IQOS, among young Korean adults. Tob Control 2018;27(suppl 1):s74-s77 [FREE Full text] [CrossRef] [Medline]
- Sutanto E, Miller C, Smith DM, O'Connor RJ, Quah ACK, Cummings KM, et al. Prevalence, use behaviors, and preferences among users of heated tobacco products: findings from the 2018 ITC Japan survey. Int J Environ Res Public Health 2019;16(23):4630 [FREE Full text] [CrossRef] [Medline]
- IQOS in the U.S. Truth Initiative. 2020. URL: https://truthinitiative.org/research-resources/emerging-tobacco-products/iqos-us [accessed 2023-02-08]
- Gao Y, Xie Z, Sun L, Xu C, Li D. Electronic cigarette-related contents on Instagram: observational study and exploratory analysis. JMIR Public Health Surveill 2020;6(4):e21963 [FREE Full text] [CrossRef] [Medline]
- Buchner J. ImageHash 4.0. 023 Python Software Foundation. URL: https://pypi.org/project/ImageHash/4.0/ [accessed 2023-02-09]
- Bradley EH, Curry LA, Devers KJ. Qualitative data analysis for health services research: developing taxonomy, themes, and theory. Health Serv Res 2007;42(4):1758-1772 [FREE Full text] [CrossRef] [Medline]
- Marta A. IQOS 3 Duo heated tobacco device. Wikimedia Commons. 2021 Nov 16. URL: https://commons.wikimedia.org/wiki/File:IQOS_3_Duo.jpg [accessed 2023-02-21]
- Lee C. HEETS and Marlboro heatsticks. Flickr. 2019 Apr 04. URL: https://www.flickr.com/photos/27954114@N05/46841139954 [accessed 2023-01-21]
- ACBSA. The IQOS of Philip Morris International is a heated tobacco smoking device (center) into which is inserted a short cigarette (charger on the left and cigarette packs on the right). Wikimedia Commons. 2017 Apr 04. URL: https://commons.wikimedia.org/wiki/File:IQOS.jpg [accessed 2023-02-21]
- Tokumeigakarinoaoshima. An IQOS store in Japan. Wikimedia Commons. 2018 Jul 25. URL: https://commons.wikimedia.org/wiki/File:IQOS_STORE_UMEDA.jpg [accessed 2023-02-21]
- Jackler RK, Ramamurthi D, Axelrod AK, Jung JK, Louis-Ferdinand NG, Reidel JE, et al. Global marketing of IQOS, the Philip Morris campaign to popularize “heat not burn” tobacco. SRITA: Stanford University School of Medicine. 2020. URL: https://tobacco-img.stanford.edu/wp-content/uploads/2021/07/21231822/IQOS_Paper_2-21-2020F.pdf [accessed 2023-02-08]
- Voorveld HAM, van Noort G, Muntinga DG, Bronner F. Engagement with social media and social media advertising: the differentiating role of platform type. J Advert 2018;47(1):38-54. [CrossRef]
- Youn S, Kim S. Understanding ad avoidance on Facebook: antecedents and outcomes of psychological reactance. Comput Hum Behav 2019;98:232-244 [FREE Full text] [CrossRef]
- Almazyad F, Shah P, Loiacono ET. Social media activism for resurrecting deleted brands: the role of consumer's psychological reactance. J Brand Manag 2023 [FREE Full text] [CrossRef]
- Social media fact sheet. Pew Research Center. 2022. URL: https://www.pewresearch.org/internet/fact-sheet/social-media/ [accessed 2023-02-08]
- Attribution-ShareAlike 4.0 International (CC BY-SA 4.0). Creative Commons. URL: https://creativecommons.org/licenses/by-sa/4.0/
- Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0). Creative Commons. 2023 Mar 09. URL: https://creativecommons.org/licenses/by-nc-nd/4.0/
Abbreviations
FDA: Food and Drug Administration |
HTP: heated tobacco product |
IQOS: I Quit Ordinary Smoking |
PMI: Philip Morris International |
Edited by A Mavragani; submitted 08.10.22; peer-reviewed by E de Quincey, S Beasley; comments to author 09.01.23; revised version received 30.01.23; accepted 31.01.23; published 15.03.23
Copyright©Jiarui Chen, Siyu Xue, Zidian Xie, Dongmei Li. Originally published in JMIR Formative Research (https://formative.jmir.org), 15.03.2023.
This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR Formative Research, is properly cited. The complete bibliographic information, a link to the original publication on https://formative.jmir.org, as well as this copyright and license information must be included.