JMIR Formative Research

Family caregivers of children and youth with neurodevelopmental disabilities report higher levels of stress, anxiety, and depression than other caregivers, yet few evidence-based mental health services are available to support them. Our previous research demonstrated that caregivers benefitted from our in-person group-based acceptance and commitment training (ACT) workshop, which increased their psychological flexibility and improved their mental well-being. During the COVID-19 pandemic, we adapted this intervention to be delivered virtually.

LookUpTrials is a clinician-facing digital platform designed to support point-of-care navigation of institution-specific oncology clinical trials, incorporating artificial intelligence–assisted summarization and search functionalities. While embedding curated trial knowledge tools in community oncology workflows is feasible, the human infrastructure required to sustain high-quality, up-to-date trial data over time remains underexplored.

As physical education classes are lost to budget cuts and recess is canceled to meet standardized testing goals, the modern school day has become dominated by sedentary digital activities. To reverse this trend, current interventions have focused on reducing screen time. However, instead of fighting this digital invasion, this study examined the use of technology, specifically mixed reality, to turn screen time from sedentary into active time, promoting physical activity in a classroom setting.

This research letter provides formative evidence from a cross-sectional analysis of 118 TikTok videos under #NaturalRemedies, identifying content formats and expertise cues associated with higher engagement, while also demonstrating the feasibility of using engagement metrics and thematic coding to analyze health narratives on emerging platforms such as TikTok.

People of sub-Saharan African and Caribbean descent are significantly more likely to be diagnosed with psychotic disorders than other ethnic groups in the United Kingdom. The National Institute for Health and Care Excellence in the United Kingdom recommends family therapy as a clinically effective treatment for the management of psychosis. The National Institute for Health and Care Excellence also recommends that family interventions should be culturally informed to meet the needs of an increasingly ethnically diverse population. People from minoritized backgrounds are rarely offered family therapy; however, the rise in digital mental health worldwide offers unique opportunities to support culturally informed approaches at scale and at a low cost.

Sustaining evidence-based health care programs is challenging, especially in clinical settings with high staff turnover. GRECC Connect is an evidence-based telemedicine service that provides geriatric specialty care to rural patients through a hub-and-spoke model between US Department of Veterans Affairs medical center “hubs” and community-based outpatient clinic (CBOC) “spokes.” Four geographically diverse GRECC Connect hub sites (of 19 total) volunteered to implement a “geriatric referral navigator” role to address the challenge of sustaining use of this program in rural CBOCs.

American Indian/Alaska Native (AI/AN) people represent a culturally diverse people group within the United States. AI/AN people experience some of the most severe health disparities in the United States, including behavioral health. A quarter of AI/AN people in the United States live on tribal lands, experiencing significant barriers to mental health resources and broadband infrastructure for telehealth. We developed Amplifying Resilience Over Restricted Internet Access (ARORA)—a mobile health (mHealth) smartphone app, promoting mindfulness practices and community building through AI/AN culture and values. Originally co-designed with both Hopi/Tewa and Navajo youth and adults, this study evaluated app resonance among Hopi/Tewa youth, supporting its iterative design. While we initially planned in-person user testing, this was moved online due to the COVID-19 pandemic.

Due to the colonization of tobacco plants by European settlers and the subsequent intensive marketing of commercial tobacco products to American Indian and Alaska Native (AI/AN) communities in the United States, commercial cigarette smoking accounts for half of all deaths among AI/AN people. Limited awareness, access to treatment, and the absence of culturally relevant, effective smoking cessation interventions contribute to these high death rates.

There is a growing interest in developing novel psychological interventions for eating disorders, with an emphasis on targeting maintaining factors. One hypothesized mechanism underlying illness maintenance is the experience of an “inner eating disorder voice,” which reinforces maladaptive thoughts, emotions, and behaviors. Preliminary studies suggest that the eating disorder voice is common among patients and is linked to greater illness severity.

Compared with other mental health problems, self-directed interventions for gambling problems lack in quantity, accessibility, and in some cases, evidence base. Moreover, engagement with these interventions remains modest. Mobile apps may be a viable format to deliver self-directed interventions that enhance user engagement.

Discharge planning (DP) is crucial for care continuity after a hospital stay but remains complex due to organizational constraints, interprofessional coordination, and administrative demands. Despite ongoing digitalization efforts, many health technologies overlook the sociotechnical nature of discharge processes, limiting acceptance and integration into clinical workflows.

While artificial intelligence (AI)–assisted diagnostic software holds promise for improving diagnostic efficiency and reducing disparities in health care delivery, its effective implementation in lower-tier health care settings remains limited in China. Most existing studies have focused on algorithm performance, while real-world implementation strategies remain underexplored, particularly in resource-constrained clinical environments.