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Efficient Online Recruitment of Patients With Depressive Symptoms Using Social Media: Cross-Sectional Observational Study

Efficient Online Recruitment of Patients With Depressive Symptoms Using Social Media: Cross-Sectional Observational Study

In medical and psychological research, generating valid study results by collecting data from large representative samples is essential [13]. For many research teams, recruiting the number of participants needed on time and within budget limitations becomes a major challenge [14]. Over 80% of trials worldwide fail to complete patient recruitment within the initially planned time frame, with insufficient case numbers being the primary reason for discontinuing 55% of all studies [15].

Carolin Haas, Lisa Klein, Marlene Heckl, Marija Kesić, Ann-Katrin Rueß, Jochen Gensichen, Karoline Lukaschek, Tobias Kruse, POKAL-Group

JMIR Ment Health 2025;12:e65920

The Effectiveness of the Be Prepared mHealth App on Recovery of Physical Functioning After Major Elective Surgery: Multicenter Randomized Controlled Trial

The Effectiveness of the Be Prepared mHealth App on Recovery of Physical Functioning After Major Elective Surgery: Multicenter Randomized Controlled Trial

Patients in the intervention group filled in the Physical Activity Readiness Questionnaire (PAR-Q) before starting the intervention to determine whether they could safely perform physical activity [16,17]. Patients who were scheduled to receive instructions on increasing physical activity and muscle strengthening through the app were contacted by a member of the research team when answering yes to one or more questions in the PAR-Q.

Miriam van der Velde, Marike van der Leeden, Edwin Geleijn, Cindy Veenhof, Karin Valkenet, Be Prepared Group

JMIR Mhealth Uhealth 2025;13:e58703

Mobile Therapeutic Attention for Treatment-Resistant Schizophrenia (m-RESIST) Solution for Improving Clinical and Functional Outcomes in Treatment-Resistant Schizophrenia: Prospective, Multicenter Efficacy Study

Mobile Therapeutic Attention for Treatment-Resistant Schizophrenia (m-RESIST) Solution for Improving Clinical and Functional Outcomes in Treatment-Resistant Schizophrenia: Prospective, Multicenter Efficacy Study

Specific digital interventions include a tablet app for patients with schizophrenia, designed to assess and record satisfaction with life and treatment domains, facilitating discussions between patients and nurses [45]. Another tablet app addresses concerns raised by patients with psychosis, providing methods for clinicians and patients to collaboratively explore and manage issues [46].

Jussi Seppälä, Eva Grasa, Anna Alonso-Solis, Alexandra Roldan-Bejarano, Marianne Haapea, Matti Isohanni, Jouko Miettunen, Johanna Caro Mendivelso, Cari Almazán, Katya Rubinstein, Asaf Caspi, Zolt Unoka, Kinga Farkas, Elisenda Reixach, Jesus Berdun, Judith Usall, Susana Ochoa, Iluminada Corripio, Erika Jääskeläinen, m-Resist Group

JMIR Hum Factors 2025;12:e67659

Machine Learning Model for Predicting Coronary Heart Disease Risk: Development and Validation Using Insights From a Japanese Population–Based Study

Machine Learning Model for Predicting Coronary Heart Disease Risk: Development and Validation Using Insights From a Japanese Population–Based Study

Therefore, this dataset is adequate to answer the research questions. Missing data analysis was conducted, and variables with more than 30% missing values were excluded to enhance model robustness. Missing data were imputed using Multivariate Imputation by Chained Equations. See Multimedia Appendix 1 for details on the percentage of missing data for each variable before imputation.

Thien Vu, Yoshihiro Kokubo, Mai Inoue, Masaki Yamamoto, Attayeb Mohsen, Agustin Martin-Morales, Research Dawadi, Takao Inoue, Jie Ting Tay, Mari Yoshizaki, Naoki Watanabe, Yuki Kuriya, Chisa Matsumoto, Ahmed Arafa, Yoko M Nakao, Yuka Kato, Masayuki Teramoto, Michihiro Araki

JMIR Cardio 2025;9:e68066

Effect of Early Treatment of Spasticity After Stroke on Motor Recovery: Protocol for the Baclotox Multicenter, Double-Blind, Double-Dummy Randomized Controlled Trial

Effect of Early Treatment of Spasticity After Stroke on Motor Recovery: Protocol for the Baclotox Multicenter, Double-Blind, Double-Dummy Randomized Controlled Trial

Because of the different modes of administration of these treatments, each group receives both an injection and oral tablets. The study therefore comprises three arms: (1) a “toxin” group treated with an injection of botulinum toxin and placebo oral baclofen; (2) a “baclofen” group treated with oral baclofen and an injection of placebo botulinum toxin; and (3) a double “placebo” group treated with placebo oral baclofen and an injection of placebo botulinum toxin.

Emmeline Montane, Nabila Brihmat, Camille Cormier, Claire Thalamas, Vanessa Rousseau, Gerard Tap, Xavier De Boissezon, Evelyne Castel-Lacanal, Baclotox Group, Philippe Marque

JMIR Res Protoc 2025;14:e62951

Telehealth Initiative to Enhance Primary Care Access in Brazil (UBS+Digital Project): Multicenter Prospective Study

Telehealth Initiative to Enhance Primary Care Access in Brazil (UBS+Digital Project): Multicenter Prospective Study

Data collection was conducted using the REDCap (Research Electronic Data Capture) database, and all information was anonymously recorded. All data collected and analyzed in this study were fully anonymized prior to use. No personally identifiable information was retained or included in any part of the dataset. The research team implemented strict data management procedures to ensure participant confidentiality throughout the study, in compliance with ethical and legal standards.

Celina de Almeida Lamas, Patrícia Gabriela Santana Alves, Luciano Nader de Araújo, Ana Beatriz de Souza Paes, Ana Claudia Cielo, Luciana Maciel de Almeida Lopes, André Longo Araújo de Melo, Thais Yokoyama, Clarice Pagani Savastano, Paula Gobi Scudeller, Carlos Carvalho, Digital Primary Health Unit HCFMUSP Study Group

J Med Internet Res 2025;27:e68434

School-Based Virtual Reality Programming for Obtaining Moderate-Intensity Exercise Among Children With Disabilities: Pre-Post Feasibility Study

School-Based Virtual Reality Programming for Obtaining Moderate-Intensity Exercise Among Children With Disabilities: Pre-Post Feasibility Study

The purpose of this 1-year feasibility study was to work with a community engagement group to develop and test the implementation of a VR HMD exergaming program for children with special needs at a high school. The overall purpose of this study was to identify a replicable protocol that could be implemented within the daily operations of a high school through the following research questions: How much exercise can students feasibly fit within a school-based program?

Byron Lai, Ashley Wright, Bailey Hutchinson, Larsen Bright, Raven Young, Drew Davis, Sultan Ali Malik, James H Rimmer, Pelham High Community Engagement Group

JMIR Form Res 2025;9:e65801

Disease Prediction Using Machine Learning on Smartphone-Based Eye, Skin, and Voice Data: Scoping Review

Disease Prediction Using Machine Learning on Smartphone-Based Eye, Skin, and Voice Data: Scoping Review

After deciding on the topic of research, we identified the steps to be taken for the literature review as follows: Search criteria Literature assembly Study selection Research questions Inclusion and exclusion criteria Full-text paper assessment Numerous studies have conducted literature reviews to assess the use of machine learning for disease prediction.

Research Dawadi, Mai Inoue, Jie Ting Tay, Agustin Martin-Morales, Thien Vu, Michihiro Araki

JMIR AI 2025;4:e59094