TY - JOUR AU - Oscarsson, Martin AU - Hammarbäck, Sandra AU - Blom Wiberg, Karolina AU - Rozental, Alexander AU - Ginsberg, Ylva AU - Carlbring, Per AU - Andersson, Gerhard AU - Jönsson, Fredrik PY - 2025 DA - 2025/5/29 TI - Web-Based Stress Management for Working Adults With Attention-Deficit/Hyperactivity Disorder (ADHD): Single-Arm, Open Pilot Trial JO - JMIR Form Res SP - e66388 VL - 9 KW - attention deficit disorder with hyperactivity KW - cognitive behavioral therapy KW - quality of life KW - pilot projects KW - internet-based intervention AB - Background: National and international guidelines advocate for a multimodal approach to treating adult attention-deficit/hyperactivity disorder (ADHD), combining pharmacotherapy with psychological interventions. While recent reviews support cognitive behavioral therapy (CBT) as a viable treatment for ADHD in adults, evidence remains limited. Another challenge is the availability of psychological interventions, with stimulants remaining the primary treatment choice for adults with ADHD. One promising approach to increasing access to psychological interventions is the dissemination of internet-delivered CBT. Objective: This study evaluated the feasibility, acceptability, and effects of a guided web-based stress management program specifically designed for working adults with ADHD. The intervention aimed to enhance quality of life by addressing stress, exhaustion, anxiety, and depression, commonly experienced by this population. Methods: Thirty-six participants took part in a single-arm open trial, with assessments before, during, and after the intervention. The intervention consisted of 12 modules based on CBT principles, focusing on executive functioning, stress management, and emotion regulation, with clinician support on demand. Primary and secondary outcomes included quality of life (Adult ADHD Quality of Life Scale [AAQoL]), perceived stress (Perceived Stress Scale [PSS-10]), exhaustion (Karolinska Exhaustion Disorder Scale [KEDS]), anxiety (Generalized Anxiety Disorder 7-item Scale [GAD-7]), depression (Patient Health Questionnaire [PHQ-9]), and ADHD symptoms (the World Health Organization Adult ADHD Self-Report Scale [ASRS]). Results: Results indicated a statistically and clinically significant improvement in quality of life (Cohen d=0.84), and a reduction in ADHD symptoms (d=0.98), as well as statistically significant reductions in perceived stress (d=0.83), exhaustion (d=1.12), anxiety (d=1.70), and depression (d=1.25). Improvements were sustained at a 12-week follow-up. A clinically significant improvement in quality of life was observed in 36% (13/36) of participants. Participants reported high satisfaction with the program and the guidance. Adherence was high, with an overall assessment response rate of 84%, a mean of 78% of modules opened, and no explicit dropouts. Twelve of the 36 participants reported negative effects. Qualitative content analysis of participants’ written feedback revealed positive experiences and suggestions for improvement. Conclusions: This study suggests promise for web-delivered interventions tailored to the needs of adults with ADHD, pending further research and development in controlled studies. Trial Registration: OSF Registries osf.io/u2cdj; https://osf.io/u2cdj SN - 2561-326X UR - https://formative.jmir.org/2025/1/e66388 UR - https://doi.org/10.2196/66388 DO - 10.2196/66388 ID - info:doi/10.2196/66388 ER -