TY  - JOUR
AU  - van Barneveld, Esther
AU  - Lim, Arianne
AU  - van Hanegem, Nehalennia
AU  - van Osch, Frits
AU  - Vork, Lisa
AU  - Kruimel, Joanna
AU  - Bongers, Marlies
AU  - Leue, Carsten
PY  - 2023
DA  - 2023/3/3
TI  - Real-time Symptom Assessment in Patients With Endometriosis: Psychometric Evaluation of an Electronic Patient-Reported Outcome Measure, Based on the Experience Sampling Method
JO  - JMIR Form Res
SP  - e29480
VL  - 7
KW  - endometriosis
KW  - pelvic pain
KW  - positive affect
KW  - negative affect
KW  - patient-reported outcome measure
KW  - momentary symptom assessment
KW  - experience sampling method
KW  - pain
KW  - PROM
KW  - outcome
KW  - patient-reported
KW  - assessment
KW  - symptom
KW  - sampling
KW  - method
KW  - evaluation
KW  - psychometric
KW  - real-time
KW  - prospective
AB  - Background: The experience sampling method (ESM) holds advantages over traditional retrospective questionnaires including a high ecological validity, no recall bias, the ability to assess fluctuation of symptoms, and the ability to analyze the temporal relationship between variables. Objective: This study aimed to evaluate the psychometric properties of an endometriosis-specific ESM tool. Methods: This is a short-term follow-up prospective study, including patients with premenopausal endometriosis aged ≥18 years who reported dysmenorrhea, chronic pelvic pain, or dyspareunia between December 2019 and November 2020. An ESM-based questionnaire was sent out by a smartphone application 10 times a day during 1 week on randomly chosen moments. Additionally, patients completed questionnaires concerning demographics, end-of-day pain scores, and end-of-week symptom scores. The psychometric evaluation included compliance, concurrent validity, and internal consistency. Results: Twenty-eight patients with endometriosis completed the study. Compliance for answering the ESM questions was as high as 52%. End-of-week pain scores were higher than ESM mean scores and showed peak reporting. ESM scores showed strong concurrent validity when compared with symptoms scored by the Gastrointestinal Symptom Rating Scale–Irritable Bowel Syndrome, 7-item Generalized Anxiety Disorders Scale, 9-question Patient Health Questionnaire, and the majority of questions of the 30-item Endometriosis Health Profile. Cronbach α coefficients demonstrated a good internal consistency for abdominal symptoms, general somatic symptoms, and positive affect, and an excellent internal consistency for negative affect. Conclusions: This study supports the validity and reliability of a newly developed electronic instrument for the measurement of symptoms in women with endometriosis, based on momentary assessments. This ESM patient-reported outcome measure has the advantage of providing a more detailed view on individual symptom patterns and offers the possibility for patients to have insight in their symptomatology, leading to more individualized treatment strategies that can improve the quality of life of women with endometriosis. 
SN  - 2561-326X
UR  - https://formative.jmir.org/2023/1/e29480
UR  - https://doi.org/10.2196/29480
UR  - http://www.ncbi.nlm.nih.gov/pubmed/36867439
DO  - 10.2196/29480
ID  - info:doi/10.2196/29480
ER  -