%0 Journal Article
%@ 2561-326X
%I JMIR Publications
%V 6
%N 6
%P e38113
%T Design and Preliminary Findings of Adherence to the Self-Testing for Our Protection From COVID-19 (STOP COVID-19) Risk-Based Testing Protocol: Prospective Digital Study
%A Herbert,Carly
%A Kheterpal,Vik
%A Suvarna,Thejas
%A Broach,John
%A Marquez,Juan Luis
%A Gerber,Ben
%A Schrader,Summer
%A Nowak,Christopher
%A Harman,Emma
%A Heetderks,William
%A Fahey,Nisha
%A Orvek,Elizabeth
%A Lazar,Peter
%A Ferranto,Julia
%A Noorishirazi,Kamran
%A Valpady,Shivakumar
%A Shi,Qiming
%A Lin,Honghuang
%A Marvel,Kathryn
%A Gibson,Laura
%A Barton,Bruce
%A Lemon,Stephenie
%A Hafer,Nathaniel
%A McManus,David
%A Soni,Apurv
%+ Division of Clinical Informatics, Department of Medicine, University of Massachusetts Chan Medical School, 55 Lake Avenue North, Worcester, MA, 01655, United States, 1 774 442 4107, apurv.soni@umassmed.edu
%K COVID-19
%K rapid antigen tests
%K COVID-19 testing
%K infectious disease
%K disease spread
%K prevention
%K coronavirus
%K adherence
%K reporting
%K mHealth
%K health application
%K mobile health
%K digital health
%K public health
%K surveillance
%K health care
%K smartphone app
%K vaccination
%K digital surveillance
%D 2022
%7 16.6.2022
%9 Original Paper
%J JMIR Form Res
%G English
%X Background: Serial testing for SARS-CoV-2 is recommended to reduce spread of the virus; however, little is known about adherence to recommended testing schedules and reporting practices to health departments. Objective: The Self-Testing for Our Protection from COVID-19 (STOP COVID-19) study aims to examine adherence to a risk-based COVID-19 testing strategy using rapid antigen tests and reporting of test results to health departments. Methods: STOP COVID-19 is a 12-week digital study, facilitated using a smartphone app for testing assistance and reporting. We are recruiting 20,000 participants throughout the United States. Participants are stratified into high- and low-risk groups based on history of COVID-19 infection and vaccination status. High-risk participants are instructed to perform twice-weekly testing for COVID-19 using rapid antigen tests, while low-risk participants test only in the case of symptoms or exposure to COVID-19. All participants complete COVID-19 surveillance surveys, and rapid antigen results are recorded within the smartphone app. Primary outcomes include participant adherence to a risk-based serial testing protocol and percentage of rapid tests reported to health departments. Results: As of February 2022, 3496 participants have enrolled, including 1083 high-risk participants. Out of 13,730 tests completed, participants have reported 13,480 (98.18%, 95% CI 97.9%-98.4%) results to state public health departments with full personal identifying information or anonymously. Among 622 high-risk participants who finished the study period, 35.9% showed high adherence to the study testing protocol. Participants with high adherence reported a higher percentage of test results to the state health department with full identifying information than those in the moderate- or low-adherence groups (high: 71.7%, 95% CI 70.3%-73.1%; moderate: 68.3%, 95% CI 66.0%-70.5%; low: 63.1%, 59.5%-66.6%). Conclusions: Preliminary results from the STOP COVID-19 study provide important insights into rapid antigen test reporting and usage, and can thus inform the use of rapid testing interventions for COVID-19 surveillance. 
%M 35649180
%R 10.2196/38113
%U https://formative.jmir.org/2022/6/e38113
%U https://doi.org/10.2196/38113
%U http://www.ncbi.nlm.nih.gov/pubmed/35649180