@Article{info:doi/10.2196/54817,
author="Jackson, Riley Walton
and Cao-Nasalga, Ann
and Chieng, Amy
and Pirkl, Amy
and Jagielo, Annemarie D
and Xu, Cindy
and Goldenhersch, Emilio
and Rosencovich, Nicolas
and Waitman, Cristian
and Prochaska, Judith J",
title="Adding Virtual Reality Mindful Exposure Therapy to a Cancer Center's Tobacco Treatment Offerings: Feasibility and Acceptability Single-Group Pilot Study",
journal="JMIR Form Res",
year="2024",
month="Jul",
day="23",
volume="8",
pages="e54817",
keywords="tobacco cessation; virtual reality; exposure therapy; cancer care; mobile phone",
abstract="Background: Smoking contributes to 1 in 3 cancer deaths. At the Stanford Cancer Center, tobacco cessation medication management and counseling are provided as a covered benefit. Patients charted as using tobacco are contacted by a tobacco treatment specialist and offered cessation services. As a novel addition, this study examined the acceptability of a virtual reality (VR) mindful exposure therapy app for quitting smoking called MindCotine. Objective: The objective of this study was to determine the feasibility and acceptability of offering 6 weeks of MindCotine treatment as a part of Stanford's Tobacco Treatment Services for patients seen for cancer care. Methods: As part of a single-group pilot study, the MindCotine VR program was offered to English- or Spanish-speaking patients interested in quitting smoking. Given the visual interface, epilepsy was a medical exclusion. Viewed from a smartphone with an attachable VR headset, MindCotine provides a digital environment with audiovisual content guiding mindfulness exercises (eg, breathing techniques, body awareness, and thought recognition), text-based coaching, and cognitive behavioral therapy-based self-reflections for quitting smoking. Interested patients providing informed consent were mailed a MindCotine headset and asked to use the app for 10+ minutes a day. At the end of 6 weeks, participants completed a feedback survey. Results: Of the 357 patients reached by the tobacco treatment specialist, 62 (17.3{\%}) were ineligible, 190 (53.2{\%}) were not interested in tobacco treatment services, and 78 (21.8{\%}) preferred other tobacco treatment services. Among the 105 eligible and interested in assistance with quitting, 27 (25.7{\%}) were interested in MindCotine, of whom 20 completed the informed consent, 9 used the program, and 8 completed their end-of-treatment survey. Participants using MindCotine completed, on average, 13 (SD 20.2) program activities, 19 (SD 26) journal records, and 11 (SD 12.3) coaching engagements. Of the 9 participants who used MindCotine, 4 (44{\%}) reported some dizziness with app use that resolved and 7 (78{\%}) would recommend MindCotine to a friend. In total, 2 participants quit tobacco (22.2{\%} reporting, 10{\%} overall), 2 others reduced their smoking by 50{\%} or more, and 2 quit for 24 hours and then relapsed. Conclusions: In a feasibility and acceptability pilot study of a novel VR tobacco treatment app offered to patients at a cancer center, 4 of 9 (44{\%}) reporting and 4 of 20 (20{\%}) overall substantially reduced or quit using tobacco after 6 weeks and most would recommend the app to others. Further testing on a larger sample is warranted. Trial Registration: ClinicalTrials.gov NCT05220254; https://clinicaltrials.gov/study/NCT05220254 ",
issn="2561-326X",
doi="10.2196/54817",
url="https://formative.jmir.org/2024/1/e54817",
url="https://doi.org/10.2196/54817"
}