@Article{info:doi/10.2196/14111, author="Kim, Minjin and Lee, Haeok and Allison, Jeroan", title="Challenges and Lessons Learned From a Mobile Health, Web-Based Human Papillomavirus Intervention for Female Korean American College Students: Feasibility Experimental Study", journal="JMIR Form Res", year="2020", month="Jan", day="29", volume="4", number="1", pages="e14111", keywords="mHealth; Web-based intervention; fraud; experimental design", abstract="Background: Mobile health (mHealth) and Web-based research methods are becoming more commonplace for researchers. However, there is a lack of mHealth and Web-based human papillomavirus (HPV) prevention experimental studies that discuss potential issues that may arise. Objective: This study aimed to assess the feasibility of research procedures and discuss the challenges and lessons learned from an mHealth and Web-based HPV prevention experimental study targeting female Korean American college students in the United States. Methods: A pilot randomized controlled trial (RCT) was conducted in an mHealth and Web-based platform with 104 female Korean American college students aged 18-26 years between September 2016 and December 2016. Participants were randomized to either the experimental group (a storytelling video intervention) or the comparison group (a nonnarrative, information-based intervention). Outcomes included the feasibility of research procedures (recruitment, eligibility, randomization, and retention). Results: From September 2016 to October 2016, we recorded 225 entries in our initial eligibility survey. The eligibility rate was 54.2{\%} (122/225). This study demonstrated a high recruitment rate (95.6{\%}, 111/122) and retention rate (83.7{\%}, 87/104) at the 2-month follow-up. Conclusions: Findings from this study demonstrated sufficient feasibility in terms of research procedures to justify a full-scale RCT. Given the increased possibility of invalid or misrepresentative entries in mHealth and Web-based studies, strategies for detection and prevention are critical. Trial Registration: ISRCTN Registry ISRCTN12175285; http://www.isrctn.com/ISRCTN12175285 ", issn="2561-326X", doi="10.2196/14111", url="http://formative.jmir.org/2020/1/e14111/", url="https://doi.org/10.2196/14111", url="http://www.ncbi.nlm.nih.gov/pubmed/32012036" }