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<article article-type="letter" dtd-version="2.0" xmlns:xlink="http://www.w3.org/1999/xlink">
  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">JFR</journal-id>
      <journal-id journal-id-type="nlm-ta">JMIR Form Res</journal-id>
      <journal-title>JMIR Formative Research</journal-title>
      <issn pub-type="epub">2561-326X</issn>
      <publisher>
        <publisher-name>JMIR Publications</publisher-name>
        <publisher-loc>Toronto, Canada</publisher-loc>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">v9i1e81845</article-id>
      <article-id pub-id-type="pmid">40952781</article-id>
      <article-id pub-id-type="doi">10.2196/81845</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Research Letter</subject>
        </subj-group>
        <subj-group subj-group-type="article-type">
          <subject>Research Letter</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Use of and Attitudes Toward Technology Among Young People Living With HIV in San Francisco: Cross-Sectional Study</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="editor">
          <name>
            <surname>Mavragani</surname>
            <given-names>Amaryllis</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Abua</surname>
            <given-names>Joseph</given-names>
          </name>
        </contrib>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Meena</surname>
            <given-names>Lalit</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib id="contrib1" contrib-type="author" corresp="yes">
          <name name-style="western">
            <surname>Arayasirikul</surname>
            <given-names>Sean</given-names>
          </name>
          <degrees>PhD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <address>
            <institution>The Legacy Center</institution>
            <institution>Joe C Wen School of Population and Public Health</institution>
            <institution>University of California, Irvine</institution>
            <addr-line>856 Health Sciences Quad</addr-line>
            <addr-line>Irvine, CA, 92697-3957</addr-line>
            <country>United States</country>
            <phone>1 949 824 2680</phone>
            <email>sean.arayasirikul@uci.edu</email>
          </address>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0001-7698-6206</ext-link>
        </contrib>
        <contrib id="contrib2" contrib-type="author">
          <name name-style="western">
            <surname>Turner</surname>
            <given-names>Caitlin</given-names>
          </name>
          <degrees>MPH</degrees>
          <xref rid="aff2" ref-type="aff">2</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0003-2894-2318</ext-link>
        </contrib>
        <contrib id="contrib3" contrib-type="author">
          <name name-style="western">
            <surname>Trujillo</surname>
            <given-names>Dillon</given-names>
          </name>
          <degrees>MPH</degrees>
          <xref rid="aff3" ref-type="aff">3</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0001-7990-1909</ext-link>
        </contrib>
        <contrib id="contrib4" contrib-type="author">
          <name name-style="western">
            <surname>Maycott</surname>
            <given-names>Jarett</given-names>
          </name>
          <degrees>MPH</degrees>
          <xref rid="aff4" ref-type="aff">4</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-3123-4470</ext-link>
        </contrib>
      </contrib-group>
      <aff id="aff1">
        <label>1</label>
        <institution>The Legacy Center</institution>
        <institution>Joe C Wen School of Population and Public Health</institution>
        <institution>University of California, Irvine</institution>
        <addr-line>Irvine, CA</addr-line>
        <country>United States</country>
      </aff>
      <aff id="aff2">
        <label>2</label>
        <institution>Department of Epidemiology and Biostatistics</institution>
        <institution>University of California, San Francisco</institution>
        <addr-line>San Francisco, CA</addr-line>
        <country>United States</country>
      </aff>
      <aff id="aff3">
        <label>3</label>
        <institution>Fielding School of Public Health</institution>
        <institution>Department of Community Health Sciences</institution>
        <institution>University of California, Los Angeles</institution>
        <addr-line>Los Angeles, CA</addr-line>
        <country>United States</country>
      </aff>
      <aff id="aff4">
        <label>4</label>
        <institution>Center for Public Health Research</institution>
        <institution>San Francisco Department of Public Health</institution>
        <addr-line>San Francisco, CA</addr-line>
        <country>United States</country>
      </aff>
      <author-notes>
        <corresp>Corresponding Author: Sean Arayasirikul <email>sean.arayasirikul@uci.edu</email></corresp>
      </author-notes>
      <pub-date pub-type="collection">
        <year>2025</year>
      </pub-date>
      <pub-date pub-type="epub">
        <day>15</day>
        <month>9</month>
        <year>2025</year>
      </pub-date>
      <volume>9</volume>
      <elocation-id>e81845</elocation-id>
      <history>
        <date date-type="received">
          <day>4</day>
          <month>8</month>
          <year>2025</year>
        </date>
        <date date-type="rev-request">
          <day>11</day>
          <month>8</month>
          <year>2025</year>
        </date>
        <date date-type="rev-recd">
          <day>12</day>
          <month>8</month>
          <year>2025</year>
        </date>
        <date date-type="accepted">
          <day>30</day>
          <month>8</month>
          <year>2025</year>
        </date>
      </history>
      <copyright-statement>©Sean Arayasirikul, Caitlin Turner, Dillon Trujillo, Jarett Maycott. Originally published in JMIR Formative Research (https://formative.jmir.org), 15.09.2025.</copyright-statement>
      <copyright-year>2025</copyright-year>
      <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/">
        <p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR Formative Research, is properly cited. The complete bibliographic information, a link to the original publication on https://formative.jmir.org, as well as this copyright and license information must be included.</p>
      </license>
      <self-uri xlink:href="https://formative.jmir.org/2025/1/e81845" xlink:type="simple"/>
      <abstract>
        <p>Digital technology is an important tool for engaging and delivering care to and for young people living with HIV. This research letter examines how 120 out-of-care young people living with HIV in San Francisco use digital technology, the attitudes they have toward technology, and the anxiety they feel about being without technology. Our findings emphasize the importance of being aware of the unintended consequences of digital health interventions.</p>
      </abstract>
      <kwd-group>
        <kwd>HIV/AIDS</kwd>
        <kwd>young people living with HIV</kwd>
        <kwd>digital health</kwd>
        <kwd>mental health</kwd>
        <kwd>technology use</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec sec-type="introduction">
      <title>Introduction</title>
      <p>The COVID-19 pandemic catalyzed a digital shift in our work and social engagements. Our online world has expanded immensely, with smartphone use increasing from 15% before the pandemic to 36% and tablet/PC use from 2% to 22% [<xref ref-type="bibr" rid="ref1">1</xref>]. Concerns about this increased screentime and adverse mental health outcomes, especially among young adults, persist despite research in the 1990s and early 2000s [<xref ref-type="bibr" rid="ref2">2</xref>]. The scientific literature around technology and mental health offers mixed support [<xref ref-type="bibr" rid="ref2">2</xref>]. Research on the effectiveness of digital and mobile health interventions continues to increase, and the results are promising for many health conditions, especially among young adults with chronic conditions [<xref ref-type="bibr" rid="ref3">3</xref>]. In this research letter, we present findings on digital technology use among a sample of young people living with HIV and describe their attitudes toward technology and anxiety about being without technology.</p>
    </sec>
    <sec sec-type="methods">
      <title>Methods</title>
      <sec>
        <title>Study Design and Participants</title>
        <p>We conducted a secondary data analysis of baseline data from a digital HIV navigation intervention study that used text messaging to improve HIV care linkage, retention, and viral suppression among 120 out-of-care young people living with HIV in San Francisco, California. Participants were eligible if they identified as a man who has sex with men or a trans woman, were aged between 18 and 34 years, resided in San Francisco, and were not engaged in HIV care. A digital navigator delivered motivational interviewing, social support, health education, and referrals to participants through text messaging over a period of 6 months. Study procedures were described in a prior manuscript [<xref ref-type="bibr" rid="ref4">4</xref>].</p>
      </sec>
      <sec>
        <title>Measures and Analysis</title>
        <p>We analyzed the following sociodemographic information: age, gender identity, race/ethnicity, education, employment status, and current living situation. To assess use of the internet, mobile phones, and social networking sites [<xref ref-type="bibr" rid="ref5">5</xref>], participants were asked how often (once a week or less, several times a week, once a day, or several times a day or more) they used email, text messaging, or apps; searched for information; checked social media; or sought out sexual partners or relationships on social networking sites. Positive and negative attitudes toward technology and dependence on technology [<xref ref-type="bibr" rid="ref5">5</xref>] were assessed using 6, 4, and 4 dichotomous (yes/no) items, respectively. For each of these 3 constructs, items were summed (1/0) and high and low categories created using the median score as a cutoff. To measure psychological distress [<xref ref-type="bibr" rid="ref6">6</xref>], a composite score was created by summing responses to items ranging from “none of the time” (0) to “all of the time” (5), detailing the frequencies of the following in the last month: feeling calm and peaceful, having a lot of energy, feeling downhearted and blue, and physical health or emotional problems interfering with social activities. Descriptive statistics were used to characterize variables. No missing data were recorded.</p>
      </sec>
      <sec>
        <title>Ethical Considerations</title>
        <p>The study protocol was approved by the Institutional Review Board of the University of California, San Francisco (16-19675). Participants provided signed informed consent and were remunerated US $50 for completing the baseline assessment. Data for this secondary analysis were deidentified to protect participants’ privacy and confidentiality.</p>
      </sec>
    </sec>
    <sec sec-type="results">
      <title>Results</title>
      <p>The sample was racially and ethnically diverse, with a majority of participants reporting some college or more, unstable housing, and unemployment (56.7%, 67.5%, and 64.2%, respectively). A majority of participants (87.5%) reported using text messaging several times a day or more, followed by mobile phone apps, searching for information on a mobile phone, checking social media, and seeking sexual partners and or relationships on social networking sites (80.8%, 80.0%, 61.7%, and 25.8%, respectively). While most participants (93.3%) reported high levels of positive attitudes toward technology, more than a third (39.2%) reported high levels of negative attitudes toward technology. Many (63.3%) reported high levels of anxiety being without technology. A majority of participants reported being anxious without their cell phone and without internet access (74.2% and 66.7%, respectively). Slightly more than half (53.3%) reported feeling anxious about their personal health information being available online, and nearly two-thirds (65.0%) reported being dependent on technology.</p>
      <table-wrap position="float" id="table1">
        <label>Table 1</label>
        <caption>
          <p>Demographic characteristics and use of the internet, mobile phones, and social networking sites of a study sample of young people living with HIV in San Francisco, 2016-2019 (N=120; mean age 27.8, SD 4.1 years).</p>
        </caption>
        <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
          <col width="30"/>
          <col width="30"/>
          <col width="720"/>
          <col width="0"/>
          <col width="220"/>
          <thead>
            <tr valign="top">
              <td colspan="4">
                <break/>
              </td>
              <td>Participants, n (%)</td>
            </tr>
          </thead>
          <tbody>
            <tr valign="top">
              <td colspan="5">
                <bold>Demographics</bold>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td colspan="4">
                <bold>Gender identity</bold>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Trans woman</td>
              <td colspan="2">17 (14.2)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Cisgender man</td>
              <td colspan="2">103 (85.8)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td colspan="4">
                <bold>Race/ethnicity</bold>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Black, non-Hispanic/Latinx</td>
              <td colspan="2">22 (18.3)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Hispanic/Latinx</td>
              <td colspan="2">38 (31.7)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Multiple races, non-Hispanic/Latinx</td>
              <td colspan="2">28 (23.3)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>White, non-Hispanic/Latinx</td>
              <td colspan="2">32 (26.7)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td colspan="4">
                <bold>Education</bold>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>High school/GED<sup>a</sup> or less</td>
              <td colspan="2">52 (43.3)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Some college or more</td>
              <td colspan="2">68 (56.7)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td colspan="4">
                <bold>Employment status</bold>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Unemployed</td>
              <td colspan="2">77 (64.2)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Part-time employed</td>
              <td colspan="2">24 (20.0)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Full-time employed</td>
              <td colspan="2">19 (15.8)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td colspan="4">
                <bold>Current living situation</bold>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Unstable</td>
              <td colspan="2">81 (67.5)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Stable</td>
              <td colspan="2">39 (32.5)</td>
            </tr>
            <tr valign="top">
              <td colspan="5">
                <bold>Use of the internet, mobile phones, and social networking sites</bold>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td colspan="4">
                <bold>How often do you send, receive and read e-mails (not including spam or junk mail)? (Choose one)</bold>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Once a week or less</td>
              <td colspan="2">24 (20.0)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Several times a week</td>
              <td colspan="2">23 (19.2)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Once a day</td>
              <td colspan="2">14 (11.7)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Several times a day or more</td>
              <td colspan="2">59 (49.2)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td colspan="4">
                <bold>How often do you send and receive text messages on a mobile phone?</bold>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Once a week or less</td>
              <td colspan="2">8 (6.7)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Several times a week</td>
              <td colspan="2">3 (2.5)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Once a day</td>
              <td colspan="2">4 (3.3)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Several times a day or more</td>
              <td colspan="2">105 (87.5)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td colspan="4">
                <bold>How often do you use apps (for any purpose) on a mobile phone?</bold>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Once a week or less</td>
              <td colspan="2">12 (10.0)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Several times a week</td>
              <td colspan="2">6 (5.0)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Once a day</td>
              <td colspan="2">5 (4.2)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Several times a day or more</td>
              <td colspan="2">97 (80.8)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td colspan="4">
                <bold>How often do you search for information with a mobile phone?</bold>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Once a week or less</td>
              <td colspan="2">9 (7.5)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Several times a week</td>
              <td colspan="2">10 (8.3)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Once a day</td>
              <td colspan="2">5 (4.2)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Several times a day or more</td>
              <td colspan="2">96 (80.0)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td colspan="4">
                <bold>How often do you check your social media page from your smartphone?</bold>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Once a week or less</td>
              <td colspan="2">27 (22.5)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Several times a week</td>
              <td colspan="2">12 (10.0)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Once a day</td>
              <td colspan="2">7 (5.8)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Several times a day or more</td>
              <td colspan="2">74 (61.7)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td colspan="4">
                <bold>How often do you seek sexual partners and or relationships on social networking sites?</bold>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Once a week or less</td>
              <td colspan="2">72 (60.0)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Several times a week</td>
              <td colspan="2">16 (13.3)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Once a day</td>
              <td colspan="2">1 (0.8)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Several times a day or more</td>
              <td colspan="2">31 (25.8)</td>
            </tr>
          </tbody>
        </table>
        <table-wrap-foot>
          <fn id="table1fn1">
            <p><sup>a</sup>General Educational Development.</p>
          </fn>
        </table-wrap-foot>
      </table-wrap>
      <table-wrap position="float" id="table2">
        <label>Table 2</label>
        <caption>
          <p>Attitudes toward technology and anxiety about being without technology among young people living with HIV in San Francisco, 2016-2019 (N=120).</p>
        </caption>
        <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
          <col width="30"/>
          <col width="30"/>
          <col width="720"/>
          <col width="220"/>
          <thead>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Participants, n (%)</td>
            </tr>
          </thead>
          <tbody>
            <tr valign="top">
              <td colspan="4">
                <bold>Positive attitudes toward technology</bold>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td colspan="3">
                <bold>I feel it is important to be able to find any information whenever I want online.</bold>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>No</td>
              <td>15 (12.5)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Yes</td>
              <td>105 (87.5)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td colspan="3">
                <bold>I feel it is important to be able to access my personal health information whenever I want online.</bold>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>No</td>
              <td>16 (13.3)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Yes</td>
              <td>104 (86.7)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td colspan="3">
                <bold>I feel it is important to be able to access the Internet any time I want.</bold>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>No</td>
              <td>12 (10.0)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Yes</td>
              <td>108 (90.0)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td colspan="3">
                <bold>I think it is important to keep up with the latest trends in technology.</bold>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>No</td>
              <td>29 (24.2)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Yes</td>
              <td>91 (75.8)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td colspan="3">
                <bold>Technology will provide solutions to many of our problems.</bold>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>No</td>
              <td>34 (28.3)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Yes</td>
              <td>86 (71.7)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td colspan="3">
                <bold>With technology anything is possible.</bold>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>No</td>
              <td>34 (28.3)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Yes</td>
              <td>86 (71.7)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td colspan="3">
                <bold>I feel that I get more accomplished because of technology.</bold>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>No</td>
              <td>31 (25.8)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Yes</td>
              <td>89 (74.2)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td colspan="3">
                <bold>Mean composite score (mean score 5.6, SD 1.8)</bold>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Low</td>
              <td>8 (6.7)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>High</td>
              <td>112 (93.3)</td>
            </tr>
            <tr valign="top">
              <td colspan="4">
                <bold>Negative attitudes toward technology</bold>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td colspan="3">
                <bold>New technology makes people waste too much time.</bold>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>No</td>
              <td>68 (56.7)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Yes</td>
              <td>52 (43.3)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td colspan="3">
                <bold>New technology makes life more complicated.</bold>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>No</td>
              <td>80 (66.7)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Yes</td>
              <td>40 (33.3)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td colspan="3">
                <bold>New technology makes people more isolated.</bold>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>No</td>
              <td>56 (46.7)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Yes</td>
              <td>64 (53.3)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td colspan="3">
                <bold>Mean composite score (mean score 1.3, SD 1.2)</bold>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Low</td>
              <td>73 (60.8)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>High</td>
              <td>47 (39.2)</td>
            </tr>
            <tr valign="top">
              <td colspan="4">
                <bold>Anxiety about being without technology</bold>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td colspan="3">
                <bold>I get anxious when I don’t have my cell phone.</bold>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>No</td>
              <td>31 (25.8)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Yes</td>
              <td>89 (74.2)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td colspan="3">
                <bold>I get anxious when I don't have the Internet available to me.</bold>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>No</td>
              <td>40 (33.3)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Yes</td>
              <td>80 (66.7)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td colspan="3">
                <bold>I am anxious about having my personal health information available online.</bold>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>No</td>
              <td>64 (53.3)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Yes</td>
              <td>56 (46.7)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td colspan="3">
                <bold>I am dependent on my technology.</bold>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>No</td>
              <td>42 (35.0)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Yes</td>
              <td>78 (65.0)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td colspan="3">
                <bold>Mean composite score (mean score 2.5, SD 1.5)</bold>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>Low</td>
              <td>44 (36.7)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>
                <break/>
              </td>
              <td>High</td>
              <td>76 (63.3)</td>
            </tr>
          </tbody>
        </table>
      </table-wrap>
    </sec>
    <sec sec-type="discussion">
      <title>Discussion</title>
      <p>We found that many young people living with HIV used mobile phones, social media, apps, and social networking sites on a regular basis. This high use may be a factor in participants’ experience of anxiety being without these digital technologies. Other research has found that technology dependence is an important consideration to shape the care of young people [<xref ref-type="bibr" rid="ref7">7</xref>]. Furthermore, technology can exacerbate isolation, negative social comparison, loneliness, and other poor mental health outcomes [<xref ref-type="bibr" rid="ref8">8</xref>]. This study has limited generalizability due to its study design and its focus on HIV care engagement among young people living with HIV. Despite this, it is critical to consider not only how digital technology can improve health, but also its influence on technology dependence and anxiety as unintended consequences [<xref ref-type="bibr" rid="ref9">9</xref>].</p>
    </sec>
  </body>
  <back>
    <app-group/>
    <ack>
      <p>The authors would like to thank all participants in the study. This work was funded by the Health Resources and Services Administration (award H97HA28895).</p>
    </ack>
    <notes>
      <sec>
        <title>Data Availability</title>
        <p>The datasets generated or analyzed during this study are not publicly available as they contain details that could be used to identify participants but are available from the corresponding author on reasonable request.</p>
      </sec>
    </notes>
    <fn-group>
      <fn fn-type="conflict">
        <p>None declared.</p>
      </fn>
    </fn-group>
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