<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article PUBLIC "-//NLM//DTD Journal Publishing DTD v2.0 20040830//EN" "journalpublishing.dtd"><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" dtd-version="2.0" xml:lang="en" article-type="research-article"><front><journal-meta><journal-id journal-id-type="nlm-ta">JMIR Form Res</journal-id><journal-id journal-id-type="publisher-id">formative</journal-id><journal-id journal-id-type="index">27</journal-id><journal-title>JMIR Formative Research</journal-title><abbrev-journal-title>JMIR Form Res</abbrev-journal-title><issn pub-type="epub">2561-326X</issn><publisher><publisher-name>JMIR Publications</publisher-name><publisher-loc>Toronto, Canada</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">v9i1e55670</article-id><article-id pub-id-type="doi">10.2196/55670</article-id><article-categories><subj-group subj-group-type="heading"><subject>Original Paper</subject></subj-group></article-categories><title-group><article-title>Internet Health Information&#x2013;Seeking Trend of Urinary Incontinence in Mainland China: Infodemiology Study</article-title></title-group><contrib-group><contrib contrib-type="author"><name name-style="western"><surname>Lin</surname><given-names>Shuangquan</given-names></name><degrees>MD</degrees><xref ref-type="aff" rid="aff1">1</xref></contrib><contrib contrib-type="author"><name name-style="western"><surname>Duan</surname><given-names>Lingxing</given-names></name><degrees>MD</degrees><xref ref-type="aff" rid="aff1">1</xref></contrib><contrib contrib-type="author"><name name-style="western"><surname>Lu</surname><given-names>Xiongbing</given-names></name><degrees>MD</degrees><xref ref-type="aff" rid="aff1">1</xref></contrib><contrib contrib-type="author"><name name-style="western"><surname>Chao</surname><given-names>Haichao</given-names></name><degrees>MD</degrees><xref ref-type="aff" rid="aff1">1</xref></contrib><contrib contrib-type="author"><name name-style="western"><surname>Wen</surname><given-names>Xi</given-names></name><degrees>MPH</degrees><xref ref-type="aff" rid="aff2">2</xref></contrib><contrib contrib-type="author" corresp="yes"><name name-style="western"><surname>Wei</surname><given-names>Shanzun</given-names></name><degrees>MD, PhD</degrees><xref ref-type="aff" rid="aff1">1</xref></contrib></contrib-group><aff id="aff1"><institution>Department of Urology, The Second Affiliated Hospital</institution><addr-line>Mingde Rd 1</addr-line><addr-line>Nanchang</addr-line><country>China</country></aff><aff id="aff2"><institution>Laboratory of Urology, The Second Affiliated Hospital</institution><addr-line>Nanchang</addr-line><country>China</country></aff><contrib-group><contrib contrib-type="editor"><name name-style="western"><surname>Mavragani</surname><given-names>Amaryllis</given-names></name></contrib></contrib-group><contrib-group><contrib contrib-type="reviewer"><name name-style="western"><surname>Ma</surname><given-names>Ming</given-names></name></contrib><contrib contrib-type="reviewer"><name name-style="western"><surname>Kinoshita</surname><given-names>Takuya</given-names></name></contrib></contrib-group><author-notes><corresp>Correspondence to Shanzun Wei, MD, PhD, Department of Urology, The Second Affiliated Hospital, Mingde Rd 1, Nanchang, 330000, China, 1 4588006725; <email>Zunny377@icloud.com</email></corresp></author-notes><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>23</day><month>6</month><year>2025</year></pub-date><volume>9</volume><elocation-id>e55670</elocation-id><history><date date-type="received"><day>20</day><month>12</month><year>2023</year></date><date date-type="rev-recd"><day>16</day><month>03</month><year>2025</year></date><date date-type="accepted"><day>21</day><month>03</month><year>2025</year></date></history><copyright-statement>&#x00A9; Shuangquan Lin, Lingxing Duan, Xiongbing Lu, Haichao Chao, Xi Wen, Shanzun Wei. Originally published in JMIR Formative Research (<ext-link ext-link-type="uri" xlink:href="https://formative.jmir.org">https://formative.jmir.org</ext-link>), 23.6.2025. </copyright-statement><copyright-year>2025</copyright-year><license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/"><p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (<ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/licenses/by/4.0/">https://creativecommons.org/licenses/by/4.0/</ext-link>), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR Formative Research, is properly cited. The complete bibliographic information, a link to the original publication on <ext-link ext-link-type="uri" xlink:href="https://formative.jmir.org">https://formative.jmir.org</ext-link>, as well as this copyright and license information must be included.</p></license><self-uri xlink:type="simple" xlink:href="https://formative.jmir.org/2025/1/e55670"/><abstract><sec><title>Background</title><p>Urinary incontinence (UI) is a series of clinical episodes featuring involuntary urine leakage. UI affects people in terms of their physical, emotional, and cognitive functioning, and the negative perceptions and impact on patients are not fully understood. In addition, the true demand for the treatment of UI and related issues is yet to be revealed.</p></sec><sec><title>Objective</title><p>The aim of this study is to examine the online search trend, user demand, and encyclopedia content quality related to UI on a national and regional scale on Baidu search, the major search engine in Mainland China.</p></sec><sec sec-type="methods"><title>Methods</title><p>The Baidu Index was queried using UI-related terms for the period from January 2011 to August 2023. The search volume for each term was recorded to analyze the search trend and demographic distributions. For user interest, the demand graph data and trend data were collected and analyzed.</p></sec><sec sec-type="results"><title>Results</title><p>Three search topics were identified with the 18 available UI search keywords. The total Baidu search index for all UI topics was 11,472,745. The annual percent changes (APCs) for the topic Complaint were 1.7% (<italic>P</italic>&#x003C;.05) from 2011-2021 and &#x2212;7.9% (<italic>P</italic>&#x003C;.05) from 2021-2023, and the average annual percent change (AAPC) was 0.1% (<italic>P</italic>&#x003C;.05). For the topic Inquiry, the APCs were 16% (<italic>P</italic>&#x003C;.05) from 2011 to 2016, &#x2212;27.00% from 2016 to 2019, and 21.2% (<italic>P</italic>&#x003C;.05) from 2019 to 2023, with an AAPC of 4.8%. Regarding the topic of Treatment, the APC was 20.3% from 2011-2018 (<italic>P</italic>&#x003C;.05), &#x2212;36.9% from 2018-2021 (<italic>P</italic>&#x003E;.05), and 2.2% from 2021-2023, with a &#x2212;0.4% overall AAPC. The age distribution of the population of each UI search topic inquiry shows that the search inquiries for each topic were mainly made by the population aged 30 to 39 years. People from the eastern part of China made up around 30% of each search query.</p></sec><sec sec-type="conclusions"><title>Conclusions</title><p>Web-based searching for UI topics has been continuous and traceable since January 2011. Different categorized themes within the UI topic highlight specific demands from various populations, necessitating tailored responses. Although online platforms can offer answers, medical professionals&#x2019; involvement is crucial to avoid misdiagnosis and delayed treatment.</p></sec></abstract><kwd-group><kwd>urinary incontinence</kwd><kwd>Baidu</kwd><kwd>Baidu index</kwd><kwd>Baidu encyclopedia</kwd><kwd>infodemiology</kwd><kwd>public interest</kwd><kwd>patients' concern</kwd></kwd-group></article-meta></front><body><sec id="s1" sec-type="intro"><title>Introduction</title><p>Urinary incontinence is a series of clinical episodes that involve involuntary urine leakage [<xref ref-type="bibr" rid="ref1">1</xref>]. Based on the different mechanisms and symptomatic discrepancies, major phenotypes of UI are (1) stress UI (SUI), (2) urgency UI, (3) mixed UI, and (4) overflow incontinence, along with other defined categories [<xref ref-type="bibr" rid="ref1">1</xref>,<xref ref-type="bibr" rid="ref2">2</xref>]. The frequency of UI varies greatly depending on demography, gender, and definitional differences. The surveyed prevalence ranges from 30.3% to 45% in females and 3.5% to 6% in males [<xref ref-type="bibr" rid="ref3">3</xref>]. In China, a survey of 518,465 people revealed the UI prevalence ranges from 37.1% to 45.1% [<xref ref-type="bibr" rid="ref4">4</xref>]. In men over 60, the prevalence ranges from 35% to 56.3% [<xref ref-type="bibr" rid="ref5">5</xref>,<xref ref-type="bibr" rid="ref6">6</xref>]. Additionally, the yearly expense of UI ranges from US $7.6 billion (&#x20AC;7 billion) to US $66 billion; it is estimated to rise to $82.6 billion by 2020 [<xref ref-type="bibr" rid="ref7">7</xref>,<xref ref-type="bibr" rid="ref8">8</xref>].</p><p>UI affects people&#x2019;s physical, emotional, and cognitive functioning [<xref ref-type="bibr" rid="ref9">9</xref>]; the negative perceptions of urinary leakage problems negatively impact patients and affect their psychological status and social roles, impairing their overall quality of life and well-being [<xref ref-type="bibr" rid="ref10">10</xref>]. It was reported that individuals with UI were more likely to conceal their distress and be hesitant to seek medical attention out of shame and stigma [<xref ref-type="bibr" rid="ref11">11</xref>,<xref ref-type="bibr" rid="ref12">12</xref>]. As a result, the known frequency of UI may be the tip of the iceberg [<xref ref-type="bibr" rid="ref13">13</xref>,<xref ref-type="bibr" rid="ref14">14</xref>].</p><p>Infodemiology, the study of infodemics, information distribution, and demand for online health information and misinformation, has been credited with revealing aspects of public health, social politics, and public perception, as well as guiding health professionals and patients to quality health information [<xref ref-type="bibr" rid="ref15">15</xref>-<xref ref-type="bibr" rid="ref17">17</xref>]. Infodemic research was carried out in the field of urology for both premature ejaculation and lower urinary tract symptoms, which were identified as the most widespread and concerning urologic issues [<xref ref-type="bibr" rid="ref18">18</xref>,<xref ref-type="bibr" rid="ref19">19</xref>]. Considering the possible adverse effects of UI on the well-being, quality of life, and social involvement of patients, the utilization of infodemiology as a metric may shed light on the unrecognized needs and demands of these populations through an alternative approach. Hence, this study aims to assess the online demand for UI information by analyzing search trends and inquiry distribution and user demand. Additionally, we aim to identify the most prominent issues pertaining to real-world geographic databases at present.</p></sec><sec id="s2" sec-type="methods"><title>Methods</title><sec id="s2-1"><title>Keyword Selection and Data Retrieval</title><p>The UI keywords used for the search were determined by referring to the International Urogynecological Association and International Continence Society published terminology report [<xref ref-type="bibr" rid="ref1">1</xref>,<xref ref-type="bibr" rid="ref20">20</xref>]. Based on these reports, various UI-describing keywords for both genders and multiple specific conditions were listed to avoid omission. All synonyms or complex derivatives were screened and selected to minimize language habits derived from ambiguity and bias, as previously described [<xref ref-type="bibr" rid="ref18">18</xref>,<xref ref-type="bibr" rid="ref21">21</xref>]. All available UI keywords with established temporal search trend data were categorized into 3 topics according to their connotation and are listed in <xref ref-type="supplementary-material" rid="app1">Multimedia Appendix 1</xref>.</p><p>As described in previous studies [<xref ref-type="bibr" rid="ref18">18</xref>,<xref ref-type="bibr" rid="ref21">21</xref>], three modules on the Baidu Index platform&#x2014;(1) the searching trend, (2) user demand, and (3) the demographic portrait module&#x2014;enabled the analysis of search demand by examining trends in popularity, topic-related concerns, and the geodemographic features of each topic. The Baidu search index (BSI) value is the key index that numerically scales the popularity of each search keyword. It is updated daily and is recorded at the national and subnational level [<xref ref-type="bibr" rid="ref18">18</xref>,<xref ref-type="bibr" rid="ref21">21</xref>]; therefore, further quantifying the BSI could allow for the analysis of the search trend, regional distribution, demographic preferences, and user interest. For each search keyword, the Baidu Index platform provides the BSI record for up to a decade, depending on the module, when required. Hence, the provincial and national trend data were collected from January 1, 2011, to August 31, 2023. In addition, the most recent within-range data from the geodemographic and search demand modules were collected [<xref ref-type="bibr" rid="ref18">18</xref>,<xref ref-type="bibr" rid="ref21">21</xref>].</p><p>The Baidu Index user demand platform delivers to users the most pertinent search results (&#x201C;related terms&#x201D;) for each keyword search on a weekly basis. These randomly generated related terms reflect users&#x2019; interests and queries. These data can be analyzed and ranked based on their frequency of appearance and popularity in searches.</p><p>To review the content from the Baidu Encyclopedia, the UI-related content on this popular science platform was also collected. All UI content was scored and sorted with a preliminary global quality scale assessment [<xref ref-type="bibr" rid="ref22">22</xref>]. The number of visits, word count, and other essential information were documented.</p></sec><sec id="s2-2"><title>Data Analysis</title><p>For each UI topic, each public demand trend (the specific question proposed by the users) was presented with data sequentially plotted from BSI data in chronological order starting from January 1, 2011.</p><p>The overtime trend change for each domain was determined by the annual percent change (APC) model. The APC and average annual percentage change (AAPC) are statistical measures used in epidemiology and public health to quantify trends over time in rates or proportions of events, such as disease incidence or mortality rates. They are typically calculated using regression methods, such as joinpoint regression analysis.</p><p>APC measures the average rate of change in percentage terms over a single year. It provides insights into how a particular rate or proportion has been changing annually, that is, whether it has been increasing, decreasing, or remaining stable [<xref ref-type="bibr" rid="ref23">23</xref>].</p><p>AAPC takes into account trends over multiple years, providing a summary measure of the average rate of change per year over a specified period. It gives a more comprehensive view of trends compared to APC, especially when trends are not linear. These models are designed to examine the change in popularity over a specified fixed interval of time [<xref ref-type="bibr" rid="ref21">21</xref>,<xref ref-type="bibr" rid="ref24">24</xref>,<xref ref-type="bibr" rid="ref25">25</xref>]. <italic>P</italic>&#x003C;.05 suggests that the trend is statistically significant.</p><p>For geographic disparities, the regional distribution of the demand for each UI term was computed annually based on provincial BSI values and sorted by the 7 Chinese administrative divisions as previously reported [<xref ref-type="bibr" rid="ref21">21</xref>].</p><p>In the user demand section, the top 10 most frequently appearing related words for each search keyword were listed and sorted by their weekly popularity. This shows the frequency and popularity of each search-related issue on the Baidu index. Similar to previous findings, these user demand module data were retrieved and categorized into 13 categories to clarify the users&#x2019; main concerns and implied intentions [<xref ref-type="bibr" rid="ref21">21</xref>]. These categories are (1) complaints, (2) inquiries, (3) treatment decisions, (4) health issues, (5) diagnoses, (6) hospitals and services, (7) symptom confirmation, (8) tests and examinations, (9) prognoses, (10) traditional Chinese medicine (TCM) complaints, (11) TCM inquiries, (12) TCM ingredients, and (13) TCM regimens, along with unrelated, random, or off-topic words (ie, irrelevant) [<xref ref-type="bibr" rid="ref21">21</xref>].</p></sec><sec id="s2-3"><title>Statistical Analysis</title><p>The entire database was constructed using Excel 2019 (Microsoft Corp). The APC was calculated using the joinpoint regression model (version 4.7.0.0; Statistical Research and Applications Branch, National Cancer Institute). The intergroup differences were compared with the Fisher exact test or the Kruskal-Wallis test in applicable situations. A <italic>P</italic>&#x003C;.05 was considered statistically significant. We used Prism 9 for macOS (version 9.5.0 [525]; GraphPad Software) to conduct statistical analysis and create figures.</p></sec><sec id="s2-4"><title>Ethical Considerations</title><p>We used publicly available, anonymized data that can be accessed without requiring any special permissions. Since the data are aggregated and publicly accessible, institutional review board approval was waived.</p></sec></sec><sec id="s3" sec-type="results"><title>Results</title><sec id="s3-1"><title>The Data on Trends in UI Topics Are Currently Accessible</title><p>We summarized the total UI search requests on Baidu over the past 12 years with the described search keywords. Based on the analysis of these 18 keywords, three major topics were recognized for initial classification: (1) complaint with 1 search keyword, (2) inquiry with 3 search keywords, and (3) treatment with 4 search keywords (see <xref ref-type="supplementary-material" rid="app1">Multimedia Appendix 1</xref>). The cumulative BSI of the UI keywords inside the trend module amounted to 11,472,745. Across all topics, the total value of BSI in 13 years was 8,174,724 in the complaint category, 1,671,387 in the inquiry category, and 1,626,634 in the treatment category.</p><p>Based on the annual average BSI count for each UI topic, it was observed that search requests in each topic underwent a comparable period of growth, culminating in a baseline returning trend by the conclusion of 2023. The particular APCs for the topic Complaint were 1.7% (<italic>P</italic>&#x003C;.05) from 2011 to 2021 and &#x2212;7.9% (<italic>P</italic>&#x003C;.05) from 2021 to 2023, while AACP was 0.1% (<italic>P</italic>&#x003C;.05). For the topic Inquiry, the APCs were 16.0% (<italic>P</italic>&#x003C;.05) from 2011 to 2016, &#x2013;27.00% from 2016 to 2019, and 21.2% (<italic>P</italic>&#x003C;.05) from 2019 to 2023, with an AAPC of 4.8%. Regarding the topic Treatment, the APC was 20.3% from 2011 to 2018 (<italic>P</italic>&#x003C;.05), &#x2013;36.9% from 2018 to 2021 (<italic>P</italic>&#x003E;.05), and 2.2% from 2021 to 2023, with an overall AAPC of &#x2212;0.4%. The APC trend, the joint-point, and the AAPC over time were calculated and demonstrated in <xref ref-type="fig" rid="figure1">Figure 1</xref>.</p><fig position="float" id="figure1"><label>Figure 1.</label><caption><p>Online interest in urinary incontinence topics since 2011. (A) Search trend of topics about urinary incontinence. (B) Sum BSI proportion of each topic about urinary incontinence. APC: annual percentage change; BSI: Baidu search index.</p></caption><graphic alt-version="no" mimetype="image" position="float" xlink:type="simple" xlink:href="formative_v9i1e55670_fig01.png"/></fig></sec><sec id="s3-2"><title>Geographic Disparities</title><p>The 13-year regional BSI proportions for each UI topic accompanied by a valid search record are shown in <xref ref-type="fig" rid="figure2">Figure 2</xref>. East Chinese users comprised the majority of search query contributors, accounting for 33.18%, 31.22%, and 32.07% in the Complaint, Inquiry, and Treatment categories, respectively. The regions of North China and Central China were next in succession. The demand levels in the Northeast, West China, and South China were comparable, each contributing 12%. Northwest demand rates were last, contributing 6.7%, 7.21%, and 7.19% to each subject.</p><fig position="float" id="figure2"><label>Figure 2.</label><caption><p>Online interest in urinary incontinence topics since 2011. (A) Annual trend of the BSI for each region for the topic of Complaint. (B) Total search rates of each area for the topic of Complaint. (C) Annual trend of the BSI for each region for the topic of Inquiry. (D) Total search rates for each area for the topic of Inquiry. (E) Annual trend of the BSI for each region for the topic of Treatment. (F) Total search rates for each area for the topic of Treatment. BSI: Baidu search index.</p></caption><graphic alt-version="no" mimetype="image" position="float" xlink:type="simple" xlink:href="formative_v9i1e55670_fig02.png"/></fig></sec><sec id="s3-3"><title>Demographic Differences</title><p>From the topic-specific demographic distribution analysis, searches varied in age and gender distribution. Regarding the Complaint topic, users aged 20&#x2010;29 and 30-39 years made 36.01% and 32.59% of requests. Similarly, most of the requests in the Inquiry topic came from people aged 30-39 years (33.23%), followed by people aged 20-29 years (22.72%), and finally people aged 40-49 years (21.38%). In the Treatment topic, more than 51.79% of requests originated from users over 50, and this trend continued, with only 7.3% of requests coming from users under 19 years of age. In contrast, requests from this age group were below 10% in other topics. Regarding gender disparities, women made the majority of the total requests for each subject. Although the demand for Treatment was very low, around 60% of the requests were still made by female users (<xref ref-type="fig" rid="figure3">Figure 3</xref>).</p><p>Furthermore, we discovered that some gender-specific and older adult&#x2013;restricting information was indicated in particular search keywords. Herein, an additional topic in the female, geriatric, and male categories was sorted for examination. Most requests (40.09%) for the female topic came from the 30&#x2010;39 year old demographic. For the male issue, requests from the 30&#x2010;39 year old group ranked highest, but they also shared a similar proportion, at 20%&#x2010;30%, with the second- and third-highest groups. Regarding the geriatric subject, it was seen that a majority of the requests, namely 60%, were made by users aged between 20-29 and 30-39 years. Additionally, it was found that female users made 71.47% of these requests. In contrast, requests from the 40-49 and &#x2265;50 age groups were just 13.91% and 13.91%, respectively (<xref ref-type="fig" rid="figure4">Figure 4</xref>).</p><fig position="float" id="figure3"><label>Figure 3.</label><caption><p>Population disparities in search preference for urinary incontinence topics. (A) Age disparities in search preference for urinary incontinence topics. (B) Gender disparities in search preference for urinary incontinence topics. BSI: Baidu search index.</p></caption><graphic alt-version="no" mimetype="image" position="float" xlink:type="simple" xlink:href="formative_v9i1e55670_fig03.png"/></fig><fig position="float" id="figure4"><label>Figure 4.</label><caption><p>Population disparities in search preference for urinary incontinence topics specific to the female, male, and geriatric populations. (A) Age disparities in search preference for urinary incontinence topics specific to different populations. (B) Gender disparities in search preference for urinary incontinence topics specific to different populations. BSI: Baidu search index.</p></caption><graphic alt-version="no" mimetype="image" position="float" xlink:type="simple" xlink:href="formative_v9i1e55670_fig04.png"/></fig></sec><sec id="s3-4"><title>Keywords, Related Terms, and Search Frequency</title><p>During the studied period, 7436 of the 9310 words that appeared were classified as valid user demands related to the topic. The total BSI for these user demand terms was 190,037,698, accounting for only 15.74% (190,037,698/1,207,203,466) of the overall user interest in the topic of UI. Diagnosis-related issues were the most frequent, making up 38.22% (2842/7436) of the total. Treatment- and decision-related issues, as well as complaints, followed. In terms of popularity, health issues received the most attention, accounting for 24.09%. The popularity ratios for the top 3 frequent themes were 14.67%, 14.90%, and 5.60%. This suggests that while UI requests are steady, their value might be overshadowed by other health issues that spike in search popularity. Detailed distributions of these related terms and their search frequencies are depicted in <xref ref-type="fig" rid="figure5">Figure 5</xref>. <xref ref-type="table" rid="table1">Tables 1</xref> and <xref ref-type="table" rid="table2">2</xref> present the top 3 related terms that were most frequently searched.</p><fig position="float" id="figure5"><label>Figure 5.</label><caption><p>Term categories related to urinary incontinence in the Baidu index demand graph. (A) The distribution of most-appearing related words (word units) that users inquired about in the Baidu index related to urinary incontinence. (B) The distribution of most-searched related words that users inquired about in the Baidu index related to urinary incontinence. BSI: Baidu search index; TCM: traditional Chinese medicine.</p></caption><graphic alt-version="no" mimetype="image" position="float" xlink:type="simple" xlink:href="formative_v9i1e55670_fig05.png"/></fig><table-wrap id="t1" position="float"><label>Table 1.</label><caption><p>The top 3 most-appearing related words (word units) that users inquired about in the Baidu index related to urinary incontinence.</p></caption><table id="table1" frame="hsides" rules="groups"><thead><tr><td align="left" valign="bottom">Category<sup><xref ref-type="table-fn" rid="table1fn1">a</xref></sup></td><td align="left" valign="bottom">Term 1</td><td align="left" valign="bottom">Number of times term appears</td><td align="left" valign="bottom">Term 2</td><td align="left" valign="bottom">Number of times term appears</td><td align="left" valign="bottom">Term 3</td><td align="left" valign="bottom">Number of times term appears</td></tr></thead><tbody><tr><td align="left" valign="top">A</td><td align="left" valign="top">&#x6F0F;&#x5C3F; (Urinary leakage)</td><td align="left" valign="top">203</td><td align="left" valign="top">&#x5C3F;&#x6F74;&#x7559; (Urinary retention)</td><td align="left" valign="top">112</td><td align="left" valign="top">&#x5C3F;&#x6025; (Urinary urgency)</td><td align="left" valign="top">67</td></tr><tr><td align="left" valign="top">B</td><td align="left" valign="top">&#x6F0F;&#x5C3F;&#x662F;&#x4EC0;&#x4E48;&#x539F;&#x56E0;&#x9020;&#x6210;&#x7684; (What is the cause for urinary leakage?)</td><td align="left" valign="top">101</td><td align="left" valign="top">&#x5C3F;&#x5931;&#x7981;&#x7684;&#x539F;&#x56E0; (What is the cause for urinary incontinence?)</td><td align="left" valign="top">60</td><td align="left" valign="top">&#x5973;&#x6027;&#x6F0F;&#x5C3F;&#x662F;&#x4EC0;&#x4E48;&#x539F;&#x56E0; (What is the cause for female incontinence?)</td><td align="left" valign="top">32</td></tr><tr><td align="left" valign="top">C</td><td align="left" valign="top">&#x5C3F;&#x5931;&#x7981;&#x600E;&#x4E48;&#x6CBB;&#x7597; (How to treat urinary incontinence)</td><td align="left" valign="top">79</td><td align="left" valign="top">&#x51EF;&#x683C;&#x5C14;&#x8FD0;&#x52A8; (Kegel exercise)</td><td align="left" valign="top">50</td><td align="left" valign="top">&#x7C73;&#x591A;&#x541B; (Midodrine)</td><td align="left" valign="top">39</td></tr><tr><td align="left" valign="top">D</td><td align="left" valign="top">&#x76C6;&#x5E95;&#x808C; (Pelvic muscle)</td><td align="left" valign="top">37</td><td align="left" valign="top">&#x5C3F;&#x9053;&#x62EC;&#x7EA6;&#x808C; (Sphincter urethra)</td><td align="left" valign="top">34</td><td align="left" valign="top">&#x5B50;&#x5BAB; (Uterus)</td><td align="left" valign="top">14</td></tr><tr><td align="left" valign="top">E</td><td align="left" valign="top">&#x5C3F;&#x5931;&#x7981; (Urinary incontinence)</td><td align="left" valign="top">421</td><td align="left" valign="top">&#x538B;&#x529B;&#x6027;&#x5C3F;&#x5931;&#x7981; (Stress incontinence)</td><td align="left" valign="top">258</td><td align="left" valign="top">&#x6025;&#x8FEB;&#x6027;&#x5C3F;&#x5931;&#x7981; (Urge incontinence)</td><td align="left" valign="top">198</td></tr><tr><td align="left" valign="top">F</td><td align="left" valign="top">&#x6CCC;&#x5C3F;&#x5916;&#x79D1; (Department of Urology)</td><td align="left" valign="top">4</td><td align="left" valign="top">&#x6D59;&#x6C5F;&#x7701;&#x4E2D;&#x533B;&#x9662; (Zhejiang Provincial Hospital of TCM<sup><xref ref-type="table-fn" rid="table1fn2">b</xref></sup>)</td><td align="left" valign="top">3</td><td align="left" valign="top">&#x5317;&#x4EAC;&#x5927;&#x5B66;&#x7B2C;&#x4E00;&#x533B;&#x9662; (The First Affiliated Hospital of Peking University)</td><td align="left" valign="top">2</td></tr><tr><td align="left" valign="top">G</td><td align="left" valign="top">&#x5C3F;&#x8DEF;&#x611F;&#x67D3;&#x7684;&#x75C7;&#x72B6; (Symptoms of urinary tract infection)</td><td align="left" valign="top">33</td><td align="left" valign="top">&#x524D;&#x5217;&#x817A;&#x589E;&#x751F;&#x7684;&#x75C7;&#x72B6; (Symptoms of benign prostate hyperplasia)</td><td align="left" valign="top">26</td><td align="left" valign="top">&#x5B50;&#x5BAB;&#x8131;&#x5782;&#x7684;&#x75C7;&#x72B6; (Symptoms of uterus prolapse)</td><td align="left" valign="top">21</td></tr><tr><td align="left" valign="top">H</td><td align="left" valign="top">PSA (Prostate-specific antigen)</td><td align="left" valign="top">5</td><td align="left" valign="top">&#x5C3F;&#x5E38;&#x89C4;&#x80FD;&#x68C0;&#x67E5;&#x51FA;&#x4EC0;&#x4E48; (Clinical indications from urine routine test)</td><td align="left" valign="top">5</td><td align="left" valign="top">&#x8180;&#x80F1;&#x955C; (Cystoscope)</td><td align="left" valign="top">5</td></tr><tr><td align="left" valign="top">I</td><td align="left" valign="top">&#x524D;&#x5217;&#x817A;&#x708E;&#x6709;&#x4EC0;&#x4E48;&#x75C7;&#x72B6;&#x548C;&#x5371;&#x5BB3; (Hazards and symptoms of prostatitis)</td><td align="left" valign="top">21</td><td align="left" valign="top">&#x5C3F;&#x9178;&#x9AD8;&#x6709;&#x4EC0;&#x4E48;&#x4E25;&#x91CD;&#x540E;&#x679C; (Severe consequence of hyperuricemia)</td><td align="left" valign="top">2</td><td align="left" valign="top">&#x618B;&#x5C3F;&#x7684;&#x5371;&#x5BB3; (Hazard of pee holding)</td><td align="left" valign="top">2</td></tr><tr><td align="left" valign="top">J</td><td align="left" valign="top">&#x4F24;&#x5BD2; (Febrile disease)</td><td align="left" valign="top">2</td><td align="left" valign="top">&#x820C;&#x82D4;&#x9EC4;&#x817B; (Yellow and greasy tongue fur)</td><td align="left" valign="top">2</td><td align="left" valign="top">&#x5973;&#x6027;&#x80BE;&#x865A; (&#x201D;Shen&#x201D; essence insufficiency of &#x201D;Yin&#x201D; in female)</td><td align="left" valign="top">1</td></tr><tr><td align="left" valign="top">K</td><td align="left" valign="top">&#x80BE;&#x865A;&#x7684;&#x8868;&#x73B0;&#x75C7;&#x72B6;&#x6709;&#x54EA;&#x4E9B; (Top 10 manifestations of &#x201D;Shen&#x201D; essence insufficiency)</td><td align="left" valign="top">4</td><td align="left" valign="top">&#x4E2D;&#x533B;&#x517B;&#x751F;&#x9879;&#x76EE; (Body maintenance project of TCM)</td><td align="left" valign="top">1</td><td align="left" valign="top">&#x4E2D;&#x533B;&#x600E;&#x4E48;&#x51CF;&#x80A5; (How to lose weight with TCM)</td><td align="left" valign="top">1</td></tr><tr><td align="left" valign="top">L</td><td align="left" valign="top">&#x6787;&#x6777;&#x53F6;&#x716E;&#x6C34;&#x7684;&#x529F;&#x6548;&#x4E0E;&#x4F5C;&#x7528; (Efficacy of folium eriobotryae decoct)</td><td align="left" valign="top">6</td><td align="left" valign="top">&#x4E94;&#x5473;&#x5B50;&#x7684;&#x529F;&#x6548;&#x4E0E;&#x4F5C;&#x7528; (Efficacy of <italic>Schisandra chinensis</italic>)</td><td align="left" valign="top">4</td><td align="left" valign="top">&#x5357;&#x74DC;&#x5B50;&#x7684;&#x4F5C;&#x7528;&#x4E0E;&#x529F;&#x6548; (Efficacy of cushaw seed)</td><td align="left" valign="top">3</td></tr><tr><td align="left" valign="top">M</td><td align="left" valign="top">&#x8865;&#x4E2D;&#x76CA;&#x6C14;&#x4E38;&#x7684;&#x529F;&#x6548;&#x548C;&#x4F5C;&#x7528; (Efficacy of &#x201C;BuZhongYiQiWan&#x201D; pill)</td><td align="left" valign="top">9</td><td align="left" valign="top">&#x91D1;&#x532E;&#x80BE;&#x6C14;&#x4E38; (&#x201C;JinKuiShenQiWan&#x201D; pill)</td><td align="left" valign="top">9</td><td align="left" valign="top">&#x91D1;&#x532E;&#x80BE;&#x6C14;&#x4E38;&#x7684;&#x4F5C;&#x7528;&#x4E0E;&#x529F;&#x6548; (Efficacy of &#x201C;JinKuiShenQiWan&#x201D;)</td><td align="left" valign="top">5</td></tr></tbody></table><table-wrap-foot><fn id="table1fn1"><p><sup>a</sup>A: complaint; B: etiology and causes; C: treatment and pharmaceutical; D: health care&#x2013;related terms; E: diagnosis; F: health care services and commodities; G: diagnosis confirmation; H: test and exam; I: prognosis; J: TCM diagnosis; K: TCM diagnosis confirmation; L: TCM regimen; M: TCM remedy and materials.</p></fn><fn id="table1fn2"><p><sup>b</sup>TCM: traditional Chinese medicine.</p></fn></table-wrap-foot></table-wrap><table-wrap id="t2" position="float"><label>Table 2.</label><caption><p>The top 3 most searched related words that users inquired about in the Baidu index related to urinary incontinence.</p></caption><table id="table2" frame="hsides" rules="groups"><thead><tr><td align="left" valign="bottom"/><td align="left" valign="bottom">Term 1</td><td align="left" valign="bottom">BSI</td><td align="left" valign="bottom">Term 2</td><td align="left" valign="bottom">BSI</td><td align="left" valign="bottom">Term 3</td><td align="left" valign="bottom">BSI</td></tr></thead><tbody><tr><td align="left" valign="top">A</td><td align="left" valign="top">&#x6F0F;&#x5C3F; (Urinary leakage)</td><td align="left" valign="top">1,317,720</td><td align="left" valign="top">&#x5C3F;&#x6F74;&#x7559; (Urinary leakage)</td><td align="left" valign="top">1,260,048</td><td align="left" valign="top">&#x9634;&#x9053;&#x524D;&#x58C1;&#x81A8;&#x51FA; (Anterior vaginal wall prolapse)</td><td align="left" valign="top">651,482</td></tr><tr><td align="left" valign="top">B</td><td align="left" valign="top">&#x5C3F;&#x9891;&#x7E41;&#x662F;&#x4EC0;&#x4E48;&#x539F;&#x56E0; (What are the causes of urinary frequency?)</td><td align="left" valign="top">1,454,404</td><td align="left" valign="top">&#x5C3F;&#x9891;&#x5C3F;&#x6025;&#x5C3F;&#x4E0D;&#x5C3D;&#x662F;&#x4EC0;&#x4E48;&#x539F;&#x56E0;&#x9020;&#x6210;&#x7684; (What are the causes of urinary frequency, urgency, and incomplete voiding?)</td><td align="left" valign="top">1,323,360</td><td align="left" valign="top">&#x6F0F;&#x5C3F;&#x662F;&#x4EC0;&#x4E48;&#x539F;&#x56E0;&#x9020;&#x6210;&#x7684; (What are the causes of urinary leakage?)</td><td align="left" valign="top">862,462</td></tr><tr><td align="left" valign="top">C</td><td align="left" valign="top">&#x51EF;&#x683C;&#x5C14;&#x8FD0;&#x52A8; (Kegel exercise)</td><td align="left" valign="top">1,919,912</td><td align="left" valign="top">&#x7532;&#x94B4;&#x80FA;&#x7247;&#x7684;&#x529F;&#x6548;&#x4E0E;&#x4F5C;&#x7528; (The efficacy of Mecobalamin tablet)</td><td align="left" valign="top">1,590,308</td><td align="left" valign="top">&#x63D0;&#x809B;&#x8FD0;&#x52A8;&#x600E;&#x4E48;&#x505A;&#x624D;&#x6B63;&#x786E; (How to do anus lifting [Kegel] correctly)</td><td align="left" valign="top">1,461,760</td></tr><tr><td align="left" valign="top">D</td><td align="left" valign="top">&#x77E5;&#x7F51; (CKNI.com)</td><td align="left" valign="top">18,351,618</td><td align="left" valign="top">&#x5404;&#x57CE;&#x5E02;&#x9996;&#x8F6E;&#x611F;&#x67D3;&#x9AD8;&#x5CF0;&#x671F;&#x9884;&#x6D4B; (Prediction of pandemic peak in each city)</td><td align="left" valign="top">3,739,154</td><td align="left" valign="top">&#x65B0;&#x51A0;&#x611F;&#x67D3; 5 &#x6B21;&#x5FC5;&#x6B7B; (Certain death after 5 times of covid-19 infection)</td><td align="left" valign="top">2,141,998</td></tr><tr><td align="left" valign="top">E</td><td align="left" valign="top">&#x524D;&#x5217;&#x817A;&#x708E; (Prostatitis)</td><td align="left" valign="top">2,585,588</td><td align="left" valign="top">&#x5C3F;&#x5931;&#x7981; (Urinary incontinence)</td><td align="left" valign="top">2,257,708</td><td align="left" valign="top">&#x5C3F;&#x8DEF;&#x611F;&#x67D3; (Urinary tract infection)</td><td align="left" valign="top">1,631,582</td></tr><tr><td align="left" valign="top">F</td><td align="left" valign="top">&#x4EAC;&#x4E1C; (JD.com)</td><td align="left" valign="top">7,659,590</td><td align="left" valign="top">&#x597D;&#x5927;&#x592B;&#x5728;&#x7EBF; (Haodaifu.com)</td><td align="left" valign="top">92,324</td><td align="left" valign="top">&#x533B;&#x751F; (Doctors)</td><td align="left" valign="top">82,880</td></tr><tr><td align="left" valign="top">G</td><td align="left" valign="top">&#x5C3F;&#x8DEF;&#x611F;&#x67D3;&#x7684;&#x75C7;&#x72B6; (What are the symptoms of urinary tract infections?)</td><td align="left" valign="top">4,361,232</td><td align="left" valign="top">&#x5C3F;&#x6BD2;&#x75C7;&#x7684;&#x65E9;&#x671F;&#x75C7;&#x72B6; (What are the early symptoms of uremia?)</td><td align="left" valign="top">2,467,396</td><td align="left" valign="top">&#x7CD6;&#x5C3F;&#x75C5;&#x7684;&#x75C7;&#x72B6;&#x6709;&#x54EA;&#x4E9B; (What are the symptoms of diabetes mellitus?)</td><td align="left" valign="top">1,947,950</td></tr><tr><td align="left" valign="top">H</td><td align="left" valign="top">&#x6297;&#x539F;&#x68C0;&#x6D4B;&#x600E;&#x4E48;&#x505A; (How to do antigen testing?)</td><td align="left" valign="top">3,788,050</td><td align="left" valign="top">&#x6838;&#x9178;&#x68C0;&#x6D4B;&#x591A;&#x4E45;&#x51FA;&#x7ED3;&#x679C; (How long does it take for nucleic acid testing?)</td><td align="left" valign="top">1,006,772</td><td align="left" valign="top">HPV (HPV [human papillomavirus])</td><td align="left" valign="top">315,724</td></tr><tr><td align="left" valign="top">I</td><td align="left" valign="top">&#x524D;&#x5217;&#x817A;&#x708E;&#x6709;&#x4EC0;&#x4E48;&#x75C7;&#x72B6;&#x548C;&#x5371;&#x5BB3;&#x6027; (What are the hazards and symptoms of prostatitis?)</td><td align="left" valign="top">5,092,960</td><td align="left" valign="top">&#x809B;&#x95E8;&#x53E3;&#x6478;&#x5230;&#x4E2A;&#x8F6F;&#x8F6F;&#x7684;&#x8089;&#x8981;&#x7D27;&#x561B; (Is it consequential to notice a palpable perianal mass?)</td><td align="left" valign="top">130,732</td><td align="left" valign="top">&#x809D;&#x56CA;&#x80BF;&#x662F;&#x600E;&#x4E48;&#x56DE;&#x4E8B;?&#x6709;&#x5371;&#x9669;&#x5417; (What is a hepatic cyst, is it dangerous?)</td><td align="left" valign="top">84,436</td></tr><tr><td align="left" valign="top">J</td><td align="left" valign="top">&#x813E;&#x865A; (Pi [spleen] insufficiency)</td><td align="left" valign="top">64,268</td><td align="left" valign="top">&#x4F24;&#x5BD2; (Typhoid fever)</td><td align="left" valign="top">29,578</td><td align="left" valign="top">&#x80BE;&#x9633;&#x865A; (&#x2018;Shen&#x2019; essence insufficiency of &#x2018;Yang&#x2019;)</td><td align="left" valign="top">26,398</td></tr><tr><td align="left" valign="top">K</td><td align="left" valign="top">&#x80BE;&#x865A;&#x7684;&#x8868;&#x73B0;&#x75C7;&#x72B6;&#x6709;&#x54EA;&#x4E9B; (What are the symptoms of insufficiency in Shen essence?)</td><td align="left" valign="top">608,124</td><td align="left" valign="top">&#x98CE;&#x70ED;&#x611F;&#x5192;&#x548C;&#x98CE;&#x5BD2;&#x611F;&#x5192;&#x7684;&#x75C7;&#x72B6;&#x533A;&#x522B; (Symptom differentiation of FengRe [heat wind origin] fever and FengHan [cold wind origin] cold)</td><td align="left" valign="top">433,660</td><td align="left" valign="top">&#x6E7F;&#x70ED;&#x75B9;&#x600E;&#x4E48;&#x6CBB;&#x7597;&#x80FD;&#x9664;&#x6839; (How to eradicate &#x201C;humid heat&#x201D; rashes?)</td><td align="left" valign="top">84,050</td></tr><tr><td align="left" valign="top">L</td><td align="left" valign="top">&#x9648;&#x76AE;&#x7684;&#x529F;&#x6548;&#x4E0E;&#x4F5C;&#x7528; (The efficacy of tangerine peel)</td><td align="left" valign="top">853,524</td><td align="left" valign="top">&#x77F3;&#x659B;&#x7684;&#x529F;&#x6548;&#x4E0E;&#x4F5C;&#x7528; (The efficacy of dendrobium)</td><td align="left" valign="top">808,556</td><td align="left" valign="top">&#x9EC4;&#x82AA;&#x7684;&#x529F;&#x6548;&#x4E0E;&#x4E3B;&#x6CBB; (The efficacy and indication of using astragalus membranaceus)</td><td align="left" valign="top">790,142</td></tr><tr><td align="left" valign="top">M</td><td align="left" valign="top">&#x8865;&#x4E2D;&#x76CA;&#x6C14;&#x4E38;&#x7684;&#x529F;&#x6548;&#x548C;&#x4F5C;&#x7528; (The efficacy of &#x201C;BuQiYiZhongWan&#x201D; pill)</td><td align="left" valign="top">935,942</td><td align="left" valign="top">&#x91D1;&#x532E;&#x80BE;&#x6C14;&#x4E38; (&#x201C;JinKuiShenQiWan&#x201D; pill)</td><td align="left" valign="top">647,778</td><td align="left" valign="top">&#x516D;&#x5473;&#x5730;&#x9EC4;&#x4E38; (&#x201C;LiuWeiDiHuangWan&#x201D; pill)</td><td align="left" valign="top">559,834</td></tr></tbody></table><table-wrap-foot><fn id="table2fn1"><p><sup>a</sup>A: complaint; B: etiology and causes; C: treatment and pharmaceutical; D: health care&#x2013;related terms; E: diagnosis; F: health care services and commodities; G: diagnosis confirmation; H: test and exam; I: prognosis; J: traditional Chinese medicine diagnosis; K: traditional Chinese medicine diagnosis confirmation; L: traditional Chinese medicine regimen; M: traditional Chinese medicine remedy and materials.</p></fn></table-wrap-foot></table-wrap></sec><sec id="s3-5"><title>Assessment of the Content Quality of the Baidu Encyclopedia</title><p>On the Baidu Encyclopedia platform, 40 chapters were identified and titled with UI. There were 32 chapters accessible for content reference, and each of these chapters could be matched to one of the 5-point scale standards of the global quality score system based on their content quality. There were 8 chapters removed from the analysis due to their book-introducing nature. Disparities in the accessibility of the English title and video link were reported. The number of sections, word count, and number of page visits differed significantly (<xref ref-type="table" rid="table3">Table 3</xref>).</p><table-wrap id="t3" position="float"><label>Table 3.</label><caption><p>Characteristics of the urinary incontinence content on Baidu Encyclopedia.</p></caption><table id="table3" frame="hsides" rules="groups"><thead><tr><td align="left" valign="top" colspan="2"/><td align="left" valign="top">GQS<sup><xref ref-type="table-fn" rid="table3fn1">a</xref></sup> 1 (N=13)</td><td align="left" valign="top">GQS 2 (N=7)</td><td align="left" valign="top">GQS 3 (N=4)</td><td align="left" valign="top">GQS 4 (N=3)</td><td align="left" valign="top">GQS 5 (N=5)</td><td align="left" valign="bottom"><italic>P</italic> value</td></tr></thead><tbody><tr><td align="left" valign="top" colspan="7"><bold>English title</bold></td><td align="left" valign="top">.01<sup><xref ref-type="table-fn" rid="table3fn2">b</xref></sup></td></tr><tr><td align="left" valign="top"/><td align="left" valign="top">Yes</td><td align="left" valign="top">5</td><td align="left" valign="top">0</td><td align="left" valign="top">0</td><td align="left" valign="top">0</td><td align="left" valign="top">4</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top"/><td align="left" valign="top">No</td><td align="left" valign="top">8</td><td align="left" valign="top">7</td><td align="left" valign="top">4</td><td align="left" valign="top">3</td><td align="left" valign="top">1</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top" colspan="7"><bold>Video link</bold></td><td align="left" valign="top">.04<sup><xref ref-type="table-fn" rid="table3fn2">b</xref></sup></td></tr><tr><td align="left" valign="top"/><td align="left" valign="top">Yes</td><td align="left" valign="top">1</td><td align="left" valign="top">1</td><td align="left" valign="top">0</td><td align="left" valign="top">1</td><td align="left" valign="top">4</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top"/><td align="left" valign="top">No</td><td align="left" valign="top">7</td><td align="left" valign="top">6</td><td align="left" valign="top">4</td><td align="left" valign="top">2</td><td align="left" valign="top">1</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top" colspan="2">Number of sections, median (IQR)</td><td align="left" valign="top">0 (0-0)</td><td align="left" valign="top">2 (2-2.5)</td><td align="left" valign="top">5 (3-7.75)</td><td align="left" valign="top">6 (6-7)</td><td align="left" valign="top">6 (6-7)</td><td align="left" valign="top">&#x003C;.001<sup><xref ref-type="table-fn" rid="table3fn3">c</xref></sup></td></tr><tr><td align="left" valign="top" colspan="2">Word count, median (IQR)</td><td align="left" valign="top">105 (50-252)</td><td align="left" valign="top">707 (610-780)</td><td align="left" valign="top">1334 (931.25&#x2010;1788.5)</td><td align="left" valign="top">3002 (2110&#x2010;3339.5)</td><td align="left" valign="top">1909 (1906-4633)</td><td align="left" valign="top">.002<sup><xref ref-type="table-fn" rid="table3fn3">c</xref></sup></td></tr><tr><td align="left" valign="top" colspan="2">Number of page visits, median (IQR)</td><td align="left" valign="top">4789 (1228-7592)</td><td align="left" valign="top">27,114 (15,587.5&#x2010;68,407)</td><td align="left" valign="top">8203 (6480.25&#x2010;20,747)</td><td align="left" valign="top">21,288 (14,095.5&#x2010;131,130)</td><td align="left" valign="top">329,725 (127,846-473,125)</td><td align="left" valign="top">&#x003C;.001<sup><xref ref-type="table-fn" rid="table3fn3">c</xref></sup></td></tr></tbody></table><table-wrap-foot><fn id="table3fn1"><p><sup>a</sup>GQS: global quality score.</p></fn><fn id="table3fn2"><p><sup>b</sup>Fisher exact test.</p></fn><fn id="table3fn3"><p><sup>c</sup>Kruskal-Wallis test.</p></fn></table-wrap-foot></table-wrap></sec></sec><sec id="s4" sec-type="discussion"><title>Discussion</title><sec id="s4-1"><title>Principal Findings</title><p>Using the most popular search engine, Baidu, made it possible to conduct research with the broadest conceivable national scope and depth [<xref ref-type="bibr" rid="ref21">21</xref>]. With billions of Chinese users submitting requests daily, it is possible to identify and address the care-seeking demand and decision-making conundrum quickly. To our knowledge, this study represents the initial foray into infodemiology research to elucidate patients&#x2019; perceptions and awareness of UI from a clinical and health care standpoint, drawing upon data from billions of users [<xref ref-type="bibr" rid="ref19">19</xref>,<xref ref-type="bibr" rid="ref26">26</xref>]. By analyzing a comprehensive dataset spanning 13 years at a national level, it is possible to uncover valuable insights into the prevailing trends, topics of interest, user search behavior, disease recognition, and demographic characteristics.</p><p>Within UI issues, topics can be created focusing solely on complaints, inquiries, and treatments using current search keywords. Interest in symptom complaints made up 71.25% of the total search volume, involving over 11 UI-related keywords. Inquiries and treatment requests comprised 3 words (14.57%) and 4 words (14.18%), respectively. Despite the popularity of UI complaint searches, it is important to note that there were specific types of UI complaints, such as those related to postpartum, urgency, older adult patients, and gender-specific conditions. This indicates that the Chinese population has a detailed and specific recognition of UI, requiring professional attention in each subfield. For inquiries and treatments, the search keywords were broader, focusing on exploring causes and potential remedies.</p><p>There has been less research focused on exploring the prognosis of UI compared to earlier studies on other subjects [<xref ref-type="bibr" rid="ref21">21</xref>,<xref ref-type="bibr" rid="ref26">26</xref>,<xref ref-type="bibr" rid="ref27">27</xref>]. Several variables may underpin this finding. First, compared to other commonly experienced lower urinary tract symptoms such as frequency, urgency, and incomplete urination, UI exhibits a higher degree of predictability and controllability regarding its onset and occurrence. By definition, the most dominant UI types&#x2014;SUI and mixed urinary incontinence&#x2014;addressed the feature of &#x201C;involuntary urine leakage when straining or during exerting efforts&#x201D; [<xref ref-type="bibr" rid="ref28">28</xref>,<xref ref-type="bibr" rid="ref29">29</xref>]. Dealing with a UI is contingent upon and subordinate to a specific preceding action.</p><p>Further, in other UI types, the symptoms tended to be overwhelmed by other stronger senses, such as urgency in urgent UI or being mostly asymptomatic as with neurogenic UI or true incontinence [<xref ref-type="bibr" rid="ref28">28</xref>,<xref ref-type="bibr" rid="ref29">29</xref>]. Hence, acquiring knowledge about the diagnosis, etiology, and treatment options for UI is essential for addressing the concerns of those affected by this condition. Consequently, medical practitioners must prioritize raising awareness and promoting the recognition of UI prognosis.</p><p>In this study, several search keywords were identified as inquiries about etiology and treatment options, but these words were mere variations of a simple open-ended question. Though self-assisted cyber diagnosis predisposing individuals to delay treatment has been a concern for a long time [<xref ref-type="bibr" rid="ref30">30</xref>], the limited popularity of searching for these 2 topics shows that the subjective treatment goal of UI has yet to be recognized and established [<xref ref-type="bibr" rid="ref31">31</xref>]. Therefore, local urologists still have the opportunity to fill these shoes.</p><p>The search trends for the 3 UI topics showed some similarities with an initial growth phase. The complaint topic maintained an increasing trend for 10 years, with an APC of only 1.7%, but a steady demand due to high initial search volumes and an average annual increase of 0.1%. UI inquiries and treatments were more variable. Inquiries showed sharp growth from 2016, peaking and then gradually declining by 2019. Treatment searches saw a strong increase over 8 years with an APC of 20.3%, but then the APC dropped sharply by 36.9% from 2018 to 2021. Fluctuations in search popularity may be linked to public reactions to controversies and criticisms of Baidu&#x2019;s marketing strategies [<xref ref-type="bibr" rid="ref30">30</xref>,<xref ref-type="bibr" rid="ref32">32</xref>]. However, during the initial COVID-19 outbreak in Wuhan, China, Baidu remained a key source of reliable information [<xref ref-type="bibr" rid="ref10">10</xref>,<xref ref-type="bibr" rid="ref18">18</xref>]. Hence, daily searches for UI topics remained steady at 2000 BSI, indicating a stable interest in general UI information.</p><p>Considering the geographic distribution, East China led UI searches across all 3 topics, averaging 30% of the total requests over the past 13 years. North China followed, with an average of 17%. The Northwest region consistently had the lowest average, accounting for 7% of total UI requests, which is lower than other regions, which averaged around 10%. The high number of requests from East China and North China aligns with our previous findings on the premature ejaculation issue [<xref ref-type="bibr" rid="ref21">21</xref>] due to higher economic levels and population density reported by [<xref ref-type="bibr" rid="ref33">33</xref>-<xref ref-type="bibr" rid="ref35">35</xref>]. According to Xue et al, the reported UI frequency in the female population ranged from 8.7% to 69.8%, representing approximately 43&#x2010;439 million people [<xref ref-type="bibr" rid="ref4">4</xref>]. Additionally, the prevalence of UI in males ranges from 17.3% to 35%, according to the existing literature [<xref ref-type="bibr" rid="ref36">36</xref>]. However, it is important to note that the available data may only provide a limited understanding of the overall prevalence of male UI nationally. The focus of medical professionals on this issue is significantly determined by the problematic UI situation revealed in [<xref ref-type="bibr" rid="ref2">2</xref>], and there is a shortage of comprehensive surveys on this topic. Less than 25% of survey participants sought medical consultation for UI [<xref ref-type="bibr" rid="ref36">36</xref>]. Therefore, traditional epidemiological methods may not adequately capture the full scope of morbidity among individuals affected by UI, which often remains overlooked as a clinical issue.</p><p>UI is a prevalent clinical condition that impacts individuals of both genders. The primary symptoms of UI vary between genders and age groups, as influenced by the underlying mechanisms associated with each clinical subtype [<xref ref-type="bibr" rid="ref28">28</xref>,<xref ref-type="bibr" rid="ref29">29</xref>,<xref ref-type="bibr" rid="ref37">37</xref>]. However, these clinical conditions share similarities and primarily involve involuntary urine leakage, which is not widely recognized by the general public. This is evident in the users&#x2019; search behavior, as indicated by the prevalence of related search terms. Our research shows that the majority of UI inquiries come from women, with the proportions of complaints, inquiries, and treatment-related themes being 67.15%, 68.61%, and 59.12%, respectively. The research focus among individuals aged 20&#x2010;29 and 30&#x2010;39 years primarily centers around urinary system disorders and their underlying mechanisms, comprising about 60% of research efforts within these age groups. Yet, most searches for disease treatment were from those over 50, accounting for 51.79% of all searches. This result suggests that disparities and inequalities in sociodemographic factors are a significant concern. Although relevant domestic research in Mainland China is lacking, a recent population-comparable study found that sociodemographic characteristics such as age, education, family income, and parity may have had a role in the reported occurrence rate of UI [<xref ref-type="bibr" rid="ref38">38</xref>,<xref ref-type="bibr" rid="ref39">39</xref>].</p><p>In simpler terms, varying levels of education and socioeconomic status affect how people perceive beliefs, tolerate UI symptoms, and seek health care. Additionally, aging exacerbates UI and is widely recognized as a significant risk factor [<xref ref-type="bibr" rid="ref40">40</xref>]. Moreover, socioeconomic factors greatly influence web-based search behavior on platforms such as Baidu. People from higher socioeconomic backgrounds generally have better internet access and digital literacy skills, enabling them to search for health information more effectively [<xref ref-type="bibr" rid="ref41">41</xref>,<xref ref-type="bibr" rid="ref42">42</xref>]. They tend to use precise medical terminology and look for reputable sources and research. Conversely, individuals from lower socioeconomic backgrounds face barriers like limited internet access, lower digital literacy, and less trust in web-based health information [<xref ref-type="bibr" rid="ref12">12</xref>]. They may rely on less accurate sources, and their search queries might be more symptom-focused than diagnostic. Cultural and societal influences also shape which health issues people are willing to search for and discuss openly. Higher educational attainment often leads to more proactive information-seeking behaviors and a better understanding of complex health issues. In contrast, those with lower education levels may struggle with medical terminology and have difficulty conducting effective searches [<xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref43">43</xref>].</p><p>Further analysis revealed differences in UI preferences and understanding among various groups. The retrieved search keywords indicated gender- and population-specific demands, showing terms related to men, women, postpartum, and geriatric UI issues. The demographic distribution of these specific UI concerns was also highlighted. As expected, female users made the most inquiries across all demographic-specific UI topics, including those concerning men. In terms of age distribution, the largest group of users was aged 30&#x2010;39 years, making up 40.09% of the total. This was followed by those aged 20&#x2010;29 and 40&#x2010;49 years, who accounted for 29.19% and 29.13%, respectively.</p><p>Unlike our previous study on premature ejaculation, which is a male issue with concerns coming mainly from men [<xref ref-type="bibr" rid="ref21">21</xref>], UI concerns and demands come mostly from women. Intuitively, one would expect patients to be most concerned about their conditions. However, the significant efforts and attention from women within the family context have not been fully recognized. Women play a prominent role in family health care decisions, making about 80% of these choices [<xref ref-type="bibr" rid="ref44">44</xref>]. Therefore, concerns and demands from women, who may be the wives of husbands or daughters of older adult patients, should not be overlooked. As a result, even content related to male UI issues should consider a women-friendly perspective.</p><p>Diagnosis-related issues were the most frequent, making up 38.22% of the total. Treatment- and decision-related issues, as well as complaints, followed. In terms of popularity, health issues received the most attention, accounting for 24.09%. The popularity percentages for the top 3 most frequent themes were 14.67%, 14.90%, and 5.60%, respectively. This suggests that while UI requests are steady, their value might be overshadowed by other health issues that spike in search popularity.</p><p>Among the most related words, &#x201C;urinary leakage,&#x201D; &#x201C;urinary retention,&#x201D; and &#x201C;urinary urgency&#x201D; were the most common complaints. In terms of search popularity, &#x201C;anterior vaginal wall prolapse&#x201D; ranked third among complaint words. Although these terms relate to UI symptoms, it is unclear if they reflect users&#x2019; inquiries or complaints about a symptom. Since different types of UI have similar symptoms but different causes, accurate and thorough UI assessments are needed to prevent misdiagnosis and delayed treatment.</p><p>Detrusor hyperactivity with impaired contractile function is a UI-mimicking condition [<xref ref-type="bibr" rid="ref45">45</xref>]. Characterized by involuntary urine leakage and urgency, the primary cause of this condition is a lack of detrusor contractility. The treatment for this condition is fundamentally different from that of other UI phenotypes. According to a prior prevalence survey on UI misdiagnosis, 24% of older adult nursing home residents have SUI misdiagnosed [<xref ref-type="bibr" rid="ref46">46</xref>]. Although these facilities offer professional health care services, such conditions cannot be confirmed without implementing cystometry or multichannel videourodynamic evaluation. Therefore, a worse situation of more diagnosis delay and mistreatment could occur if the potential patient only seeks out a doctor via the internet based on their perception of symptoms.</p><p>In the treatment topic, we noticed the related terms of Kegel exercise and anus lifting (<xref ref-type="table" rid="table1">Tables 1</xref> and <xref ref-type="table" rid="table2">2</xref>) were most frequently inquired about with the highest popularity. Pelvic floor muscle training is considered the primary treatment option for UI since it has been demonstrated to effectively reduce episodes of urine leakage and enhance quality of life [<xref ref-type="bibr" rid="ref47">47</xref>]. Kegel exercises are considerably more popular than other therapies [<xref ref-type="bibr" rid="ref47">47</xref>] due to their adaptability, simplicity of implementation, and low cost. However, the pelvic strengthening exercises could only moderate the weakened pelvic muscle for better stabilization and hence could mostly be effective in lower-grade UI with moderate symptoms or alleviate severe symptoms of a particular phenotype [<xref ref-type="bibr" rid="ref31">31</xref>,<xref ref-type="bibr" rid="ref47">47</xref>,<xref ref-type="bibr" rid="ref48">48</xref>].</p><p>Users who search for information on Baidu can find answers to their questions in Baidu&#x2019;s official encyclopedia [<xref ref-type="bibr" rid="ref49">49</xref>]. For UI issues, there were 40 pages describing UI issues ranging from general aspects to certain specific treatment options. Though the content quality varies, the &#x201C;must knows&#x201D; of UI, such as its phenotypes, etiologic features, and population-specific issues, were included. Although the convenience of an online encyclopedia platform is well-recognized, the quality and dependability have yet to be sufficiently accurate in resolving confusion and providing health advice [<xref ref-type="bibr" rid="ref49">49</xref>,<xref ref-type="bibr" rid="ref50">50</xref>]. Similar to the findings of Handler et al [<xref ref-type="bibr" rid="ref51">51</xref>], we found that the material on the Baidu platform of popular science is characterized by a high level of detail. However, it is essential to note that this information lacks proper categorization and even includes some inaccurate titles. As a result, not only does this situation impose additional difficulties, but it also has the potential to mislead users, with potentially severe repercussions.</p><p>Given these considerations, medical professionals should anticipate patients&#x2019; needs and identify relevant information. Adjustments in therapeutic sessions, communication, and public education are essential to address patients&#x2019; issues effectively.</p><p>There are several limitations to this study. Although Baidu is the largest search platform in Mainland China, other search engines and social media platforms are increasingly competing, which means the daily search-based BSI may not capture all online user demands. Additionally, regional differences in user preferences and political restrictions may exclude search queries from local citizens who use international search platforms legally. Furthermore, as a Chinese-based internet service, requests from foreign languages or non-Chinese minority groups are likely to be systematically excluded. Additionally, all data from the Baidu Index platform were presented in a fixed and finalized format, limiting the ability to further manipulate or reorganize the data for more flexible structural customization.</p><p>To the best of our knowledge, this study represents the initial exploration of infodemiology to address the issue of assessing public concern in the Chinese-speaking population around UI. We chose to investigate the popularity of UI because of its complex nature and the potential for a lack of interest, which can lead to hesitation and delayed treatment. By examining current trends and demand, we can understand prevailing patterns and identify patients&#x2019; main concerns. This insight allows for adjustments to health care strategies and responses to enhance Medicare services.</p></sec><sec id="s4-2"><title>Conclusion</title><p>Web-based UI searching is continuous and traceable since January 2011. Different categorized themes within the UI topic highlight specific demands from various populations, necessitating tailored responses. Although web-based platforms can offer answers, medical professionals&#x2019; involvement is crucial to avoid misdiagnosis and delayed treatment.</p></sec></sec></body><back><ack><p>Artificial intelligence or chatbot tools were solely used for language editing in this manuscript. No content generation or ideation were originated by the artificial intelligence or chatbot.</p></ack><notes><sec><title>Data Availability</title><p>The datasets generated and analyzed during this study, including search trend and demographic, are available from Baidu index platform and the corresponding author upon reasonable request.</p></sec></notes><fn-group><fn fn-type="con"><p>This study was conceptualized by SW. The methodology was designed by SW. The investigation was carried out by LS, DL, and LX. CH, DL, and LS wrote the original draft. SW, LX, and WX reviewed and edited the draft. Funding was acquired by SW. 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