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  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">JFR</journal-id>
      <journal-id journal-id-type="nlm-ta">JMIR Form Res</journal-id>
      <journal-title>JMIR Formative Research</journal-title>
      <issn pub-type="epub">2561-326X</issn>
      <publisher>
        <publisher-name>JMIR Publications</publisher-name>
        <publisher-loc>Toronto, Canada</publisher-loc>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">v5i12e31232</article-id>
      <article-id pub-id-type="pmid">34931989</article-id>
      <article-id pub-id-type="doi">10.2196/31232</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Original Paper</subject>
        </subj-group>
        <subj-group subj-group-type="article-type">
          <subject>Original Paper</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>A Patient-Reported Outcome Tool to Triage Total Hip Arthroplasty Patients to Hospital or Video Consultation: Pilot Study With Expert Panels and a Cohort of 1228 Patients</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="editor">
          <name>
            <surname>Eysenbach</surname>
            <given-names>Gunther</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Shah</surname>
            <given-names>Dr. Pankaj</given-names>
          </name>
        </contrib>
        <contrib contrib-type="reviewer">
          <name>
            <surname>McKinstry</surname>
            <given-names>Brian</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib id="contrib1" contrib-type="author" corresp="yes">
          <name name-style="western">
            <surname>Pronk</surname>
            <given-names>Yvette</given-names>
          </name>
          <degrees>MSc</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <address>
            <institution>Research Department</institution>
            <institution>Kliniek ViaSana</institution>
            <addr-line>Hoogveldseweg 1</addr-line>
            <addr-line>Mill, 5451 AA</addr-line>
            <country>Netherlands</country>
            <phone>31 485476330</phone>
            <email>y.pronk@viasana.nl</email>
          </address>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0001-5086-1501</ext-link>
        </contrib>
        <contrib id="contrib2" contrib-type="author">
          <name name-style="western">
            <surname>Pilot</surname>
            <given-names>Peter</given-names>
          </name>
          <degrees>PhD</degrees>
          <xref rid="aff2" ref-type="aff">2</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-6457-0091</ext-link>
        </contrib>
        <contrib id="contrib3" contrib-type="author">
          <name name-style="western">
            <surname>van der Weegen</surname>
            <given-names>Walter</given-names>
          </name>
          <degrees>PhD</degrees>
          <xref rid="aff3" ref-type="aff">3</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0001-9389-0644</ext-link>
        </contrib>
        <contrib id="contrib4" contrib-type="author">
          <name name-style="western">
            <surname>Brinkman</surname>
            <given-names>Justus-Martijn</given-names>
          </name>
          <degrees>MD, PhD</degrees>
          <xref rid="aff4" ref-type="aff">4</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-5862-3484</ext-link>
        </contrib>
        <contrib id="contrib5" contrib-type="author">
          <name name-style="western">
            <surname>Schreurs</surname>
            <given-names>Berend Willem</given-names>
          </name>
          <degrees>MD, PhD</degrees>
          <xref rid="aff5" ref-type="aff">5</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0003-4518-431X</ext-link>
        </contrib>
      </contrib-group>
      <aff id="aff1">
        <label>1</label>
        <institution>Research Department</institution>
        <institution>Kliniek ViaSana</institution>
        <addr-line>Mill</addr-line>
        <country>Netherlands</country>
      </aff>
      <aff id="aff2">
        <label>2</label>
        <institution>IMUKA</institution>
        <addr-line>Roosteren</addr-line>
        <country>Netherlands</country>
      </aff>
      <aff id="aff3">
        <label>3</label>
        <institution>Department of Orthopaedic Surgery</institution>
        <institution>Anna Ziekenhuis</institution>
        <addr-line>Geldrop</addr-line>
        <country>Netherlands</country>
      </aff>
      <aff id="aff4">
        <label>4</label>
        <institution>Department of Orthopaedic Surgery</institution>
        <institution>Kliniek ViaSana</institution>
        <addr-line>Mill</addr-line>
        <country>Netherlands</country>
      </aff>
      <aff id="aff5">
        <label>5</label>
        <institution>Department of Orthopaedic Surgery</institution>
        <institution>Radboud University Medical Center</institution>
        <addr-line>Nijmegen</addr-line>
        <country>Netherlands</country>
      </aff>
      <author-notes>
        <corresp>Corresponding Author: Yvette Pronk <email>y.pronk@viasana.nl</email></corresp>
      </author-notes>
      <pub-date pub-type="collection">
        <month>12</month>
        <year>2021</year>
      </pub-date>
      <pub-date pub-type="epub">
        <day>20</day>
        <month>12</month>
        <year>2021</year>
      </pub-date>
      <volume>5</volume>
      <issue>12</issue>
      <elocation-id>e31232</elocation-id>
      <history>
        <date date-type="received">
          <day>14</day>
          <month>6</month>
          <year>2021</year>
        </date>
        <date date-type="rev-request">
          <day>7</day>
          <month>9</month>
          <year>2021</year>
        </date>
        <date date-type="rev-recd">
          <day>4</day>
          <month>10</month>
          <year>2021</year>
        </date>
        <date date-type="accepted">
          <day>4</day>
          <month>10</month>
          <year>2021</year>
        </date>
      </history>
      <copyright-statement>©Yvette Pronk, Peter Pilot, Walter van der Weegen, Justus-Martijn Brinkman, Berend Willem Schreurs. Originally published in JMIR Formative Research (https://formative.jmir.org), 20.12.2021.</copyright-statement>
      <copyright-year>2021</copyright-year>
      <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/">
        <p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR Formative Research, is properly cited. The complete bibliographic information, a link to the original publication on https://formative.jmir.org, as well as this copyright and license information must be included.</p>
      </license>
      <self-uri xlink:href="https://formative.jmir.org/2021/12/e31232" xlink:type="simple"/>
      <abstract>
        <sec sec-type="background">
          <title>Background</title>
          <p>The digital transformation in health care has been accelerated by the COVID-19 pandemic. Video consultation has become the alternative for hospital consultation. It remains unknown how to select patients suitable for video consultation.</p>
        </sec>
        <sec sec-type="objective">
          <title>Objective</title>
          <p>This study aimed to develop a tool based on patient-reported outcomes (PROs) to triage total hip arthroplasty (THA) patients to hospital or video consultation.</p>
        </sec>
        <sec sec-type="methods">
          <title>Methods</title>
          <p>A pilot study with expert panels and a retrospective cohort with prospectively collected data from 1228 THA patients was executed. The primary outcome was a PRO triage tool to allocate THA patients to hospital or video consultation 6 weeks postoperatively. Expert panels defined the criteria and selected the patient-reported outcome measure (PROM) questions including thresholds. Data were divided into training and test cohorts. Distribution, floor effect, correlation, responsiveness, PRO patient journey, and homogeneity of the selected questions were investigated in the training cohort. The test cohort was used to provide an unbiased evaluation of the final triage tool.</p>
        </sec>
        <sec sec-type="results">
          <title>Results</title>
          <p>The expert panels selected moderate or severe pain and using 2 crutches as the triage tool criteria. PROM questions included in the final triage tool were numeric rating scale (NRS) pain during activity, 3-level version of the EuroQol 5 dimensions (EQ-5D-3L) questions 1 and 4, and Oxford Hip Score (OHS) questions 6, 8, and 12. Of the training cohort, 201 (201/703, 28.6%) patients needed a hospital consultation, which was statistically equal to the 150 (150/463, 32.4%) patients in the test cohort who needed a hospital consultation (<italic>P</italic>=.19).</p>
        </sec>
        <sec sec-type="conclusions">
          <title>Conclusions</title>
          <p>A PRO triage tool based on moderate or severe pain and using 2 crutches was developed. Around 70% of THA patients could safely have a video consultation, and 30% needed a hospital consultation 6 weeks postoperatively. This tool is promising for selecting patients for video consultation while using an existing PROM infrastructure.</p>
        </sec>
      </abstract>
      <kwd-group>
        <kwd>PROMs</kwd>
        <kwd>total hip arthroplasty</kwd>
        <kwd>triage tool</kwd>
        <kwd>video consultation</kwd>
        <kwd>telemedicine</kwd>
        <kwd>digital transformation</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec sec-type="introduction">
      <title>Introduction</title>
      <p>The digital transformation in health care has been accelerated by the COVID-19 pandemic. Health care institutions are challenged by precautionary measures to contain COVID-19 while continuing to provide health care. Especially, managing the physical flow of patients is challenging. After the pandemic, hospitals will begin to eliminate their waiting lists while maintaining a normal patient flow, and they will be challenged again. As a solution, video consultation has become an alternative to the traditional hospital consultation. The number of hospital consultations has dropped by 30%, and the number of telemedicine visits has increased 5-fold [<xref ref-type="bibr" rid="ref1">1</xref>].</p>
      <p>Currently, video consultation provides health care institutions and clinicians the opportunity to increase office efficacy and cost-effectiveness in an era of decreasing reimbursements and increasing time constraints [<xref ref-type="bibr" rid="ref2">2</xref>-<xref ref-type="bibr" rid="ref4">4</xref>]. From the patient’s perspective, it can also improve care efficacy and patient satisfaction as well as eliminating travel time and expenses [<xref ref-type="bibr" rid="ref1">1</xref>,<xref ref-type="bibr" rid="ref2">2</xref>]. However, not all patients might benefit from video consultation, and it is unknown how to select patients suitable for video consultation.</p>
      <p>Orthopedic associations in many countries advise hospitals to collect patient-reported outcomes (PROs) of total hip arthroplasty (THA) using selected patient-reported outcome measures (PROMs) to evaluate health care and improve patient care [<xref ref-type="bibr" rid="ref5">5</xref>,<xref ref-type="bibr" rid="ref6">6</xref>]. To prevent extra burden in time and costs, it would be efficient to apply these PROs to select which patients need a hospital consultation and who can have a video consultation instead. Therefore, the aim of this study was to develop a tool based on PROs to triage THA patients to hospital or video consultation 6 weeks postoperatively. It was hypothesized that 10% of the THA patients would need a hospital consultation, as around 90% of the performed THAs result in a favorable outcome [<xref ref-type="bibr" rid="ref7">7</xref>-<xref ref-type="bibr" rid="ref9">9</xref>].</p>
    </sec>
    <sec sec-type="methods">
      <title>Methods</title>
      <sec>
        <title>Overview</title>
        <p>A pilot study with expert panels and a retrospective cohort with prospectively collected data from THA patients was performed. Regarding the cohort, patients were included in this study if they signed the informed consent form preoperatively to allow further scientific analysis using their anonymized data. Therefore, the institutional review board ruled that formal approval was not required for this study. There were no exclusion criteria.</p>
      </sec>
      <sec>
        <title>Outcomes</title>
        <p>The primary outcome was a PRO triage tool to allocate THA patients to a hospital consultation or a video consultation for their 6-week postoperative consultation. Hospital consultation was defined as needing a physical examination or other examination, such as an X-ray, for which a patient really needed to be in the hospital. If no hospital consultation was needed, patients were allocated to a video consultation. According to the Dutch guidelines, patients should be seen 6 to 12 weeks after a THA [<xref ref-type="bibr" rid="ref10">10</xref>], which is mostly held at 6 weeks. As it is advised to collect the first postoperative PROs at 3 months and not at 6 weeks [<xref ref-type="bibr" rid="ref6">6</xref>], the 3-month PROs were considered the most appropriate for this study. Based on previous studies, the assumption was made that there are limited clinically relevant differences between PROs at 6 weeks and 3 months postoperatively [<xref ref-type="bibr" rid="ref11">11</xref>,<xref ref-type="bibr" rid="ref12">12</xref>].</p>
      </sec>
      <sec>
        <title>Measurements</title>
        <p>Measurements were divided into 3 parts: (1) expert panels defined the criteria and selected the PROM questions, including the thresholds; (2) investigation of the clinimetric qualities of selected questions or triage criteria groups in the retrospective cohort with prospectively collected data; and (3) evaluation of the final triage tool.</p>
        <sec>
          <title>Selection by Expert Panels</title>
          <p>Two expert panels were created: clinical expert panel and research expert panel. The clinical expert panel consisted of 4 high-volume THA orthopedic surgeons from 2 different health care institutions. The research expert panel consisted of 3 researchers from 2 different health care institutions. As step one, the clinical expert panel defined the clinical triage criteria for the triage tool. These clinical triage criteria were based on the clinical disabilities for which patients needed to have a physical examination or other examination, such as an X-ray. As the second step, based on the clinical triage criteria, the research expert panel selected the appropriate PROM questions, including the thresholds, based on previous studies. As step three, these questions and their thresholds were presented to the clinical expert panel to discuss if these questions and/or thresholds covered the clinical triage criteria. If no threshold was reported in previous studies, the threshold was set using clinical reasoning by the clinical expert panel. These steps resulted in the PROM questions, including the thresholds, that were determined to be clinically relevant for the triage tool.</p>
        </sec>
        <sec>
          <title>Clinimetric Qualities of Selected Questions or Triage Criteria Groups</title>
          <p>The retrospective cohort with prospectively collected data consisted of patients who underwent surgery between January 2016 and December 2018 in a medium-sized orthopedic hospital (Kliniek ViaSana, Mill, The Netherlands). Therefore, patients were characterized by an American Society of Anesthesiologists (ASA) score of I-II and BMI ≤35. Four high-volume, experienced orthopedic surgeons performed the primary posterolateral THAs. Length of stay was generally 1 or 2 days.</p>
          <p>The data included patient characteristics, PROM response rates, and PROs. Patient characteristics were age on the day of surgery, gender, preoperative BMI, ASA scores, and preoperative Charnley scores collected from the electronic patient records. Response rates were calculated as the number of returned questionnaires that were partially or totally completed divided by the number of THAs minus the number of THAs of patients who were deceased (returned questionnaires / [THAs - THAs of patients who were deceased]) [<xref ref-type="bibr" rid="ref5">5</xref>]. PROs were primary digitally collected (OnlinePROMs, Rosmalen, The Netherlands). If patients were unable to handle a computer, paper questionnaires were sent. A maximum of 2 reminders to complete the PROMs were sent [<xref ref-type="bibr" rid="ref13">13</xref>]. PROs were collected preoperatively and 3 and 12 months postoperatively according to the advice of the Dutch Orthopedic Association. This advice included the following questionnaires: numeric rating scale (NRS) pain at rest, NRS pain during activity, 3-level version of the EuroQol 5 dimensions (EQ-5D-3L), Hip disability and Osteoarthritis Outcome Score – Physical Function Shortform (HOOS-PS), Oxford Hip Score (OHS), and an anchor question about functional improvement [<xref ref-type="bibr" rid="ref6">6</xref>].</p>
          <p>Pain at rest and pain during activity were both measured using an NRS question scored from 0 (no pain) to 10 (severe pain). Quality of life was assessed using the EQ-5D-3L questionnaire consisting of 2 parts: EQ visual analogue scale (EQ VAS; 0-100, with 0 as the worst imaginable health state and 100 as the best imaginable health state) and EQ-5D descriptive system existing of 5 questions about 5 dimensions. These 5 dimensions are mobility, self-care, usual activities, pain/discomfort, and anxiety/depression, scored from 1 (no problems) to 3 (extreme problems) [<xref ref-type="bibr" rid="ref14">14</xref>]. Furthermore, hip function was measured using the HOOS-PS questionnaire, on a scale from 0 (no difficulty) to 100 (extreme difficulty). This questionnaire consists of 5 questions scored from 0 (no difficulty) to 5 (extreme difficulty) [<xref ref-type="bibr" rid="ref15">15</xref>,<xref ref-type="bibr" rid="ref16">16</xref>]. Hip function and pain were assessed using the OHS questionnaire, with scores ranging from 0 (most severe symptoms) to 48 (least symptoms). This questionnaire consists of 12 questions scored from 0 (no difficulty) to 4 (extreme difficulty) [<xref ref-type="bibr" rid="ref17">17</xref>]. Moreover, functional improvement was inquired on a 7-point Likert scale question ranging from 1 (very much deteriorated) to 7 (very much improved).</p>
          <p>Regarding the investigation of the clinimetric qualities of selected questions or triage criteria groups by the expert panels, the cohort was divided into 2 groups: training cohort of patients who underwent surgery in 2016 or 2017 and a test cohort of patients who underwent surgery in 2018. To assess which questions were appropriate for the triage tool, the following clinimetric qualities were investigated per selected question in the training cohort: distribution, floor effect, correlation, responsiveness, and PRO patient journey. PRO patient journey was defined as a change in recovery over time. Regarding distribution, if the question did not show any distinction (median and IQR on the same level), the question was found not to be an appropriate question for the triage tool. For floor effect, if more than 15% of the patients scored the worst score [<xref ref-type="bibr" rid="ref18">18</xref>], the question had a problem with the floor effect and was not an appropriate triage tool question. Investigating correlation, if the question was correlated (<italic>r</italic>≥.7) with another selected question(s) [<xref ref-type="bibr" rid="ref19">19</xref>], this question or one of the other(s) could be chosen instead of all the questions for the triage tool. Regarding responsiveness, if a question was not responsive (<italic>P</italic>&#62;.05) [<xref ref-type="bibr" rid="ref20">20</xref>,<xref ref-type="bibr" rid="ref21">21</xref>], it did not distinguish well between clinical relevance and lack of clinical relevance and was not included in the tool. Furthermore, the PRO patient journeys of patients with a worse score and of patients with a better score than the threshold were investigated. If patients with a worse score on a question at 3 months scored well on that question at 12 months, this question was not included in the triage tool. To assess which questions within the selected triage criteria group (for example pain) were appropriate for the triage tool, homogeneity was investigated per triage criteria group in the training cohort. If the homogeneity increased by removing a certain question from this group (Cronbach α&#62;.7) [<xref ref-type="bibr" rid="ref18">18</xref>,<xref ref-type="bibr" rid="ref19">19</xref>], this question did not fit in this group and could be removed from the triage tool.</p>
        </sec>
        <sec>
          <title>Evaluation of the Final Triage Tool</title>
          <p>The final triage tool was applied in the test cohort to provide an unbiased evaluation of the final tool fitted on the training dataset. Results in both cohorts were compared to investigate the hypothesis.</p>
        </sec>
      </sec>
      <sec>
        <title>Statistical Analysis</title>
        <p>Results are reported as mean (SD), median (IQR), or n (%) based on the test performed. To investigate if there was any difference in patient characteristics, response rates, and preoperative PROs between the training and test cohorts, continuous variables were first checked for a normal distribution. Second, independent <italic>t</italic> tests or Mann-Whitney <italic>U</italic> tests for continuous variables were executed depending on the distribution of the data, and Pearson chi-square or Fisher exact tests were executed for categorical variables.</p>
        <p>Distribution was investigated with a boxplot distribution, floor effect was determined by calculating the percentage of patients with a minimum score, and correlation was assessed with Spearman correlation analyses. Responsiveness was evaluated by performing Wilcoxon signed rank tests on the change in preoperative and 3-month scores [<xref ref-type="bibr" rid="ref20">20</xref>,<xref ref-type="bibr" rid="ref21">21</xref>]. The PRO patient journey of patients with a worse or better score than the threshold on a question at 3 months was evaluated by boxplot distribution at 12 months. Homogeneity was investigated with a reliability analysis, including “scale if item deleted.” Before this analysis was executed, NRS pain and EQ-5D-3L questions were recoded to the same direction as the OHS questions.</p>
        <p>Finally, the triage tool was applied for both training and test cohorts. To test the hypothesis, the numbers of hospital and video consultations for both cohorts were compared using Pearson chi-square or Fisher exact tests.</p>
        <p>An α of .05 was considered statistically significant. Statistical analyses were performed using SPSS version 25.0 (IBM Corp, Armonk, NY).</p>
      </sec>
    </sec>
    <sec sec-type="results">
      <title>Results</title>
      <sec>
        <title>Selection by Expert Panels</title>
        <p>“Having moderate or severe pain” and “using 2 crutches” were defined as the triage criteria by the clinical expert panel (step 1). For the criterion of “having moderate or severe pain,” the research expert panel selected the following PROM questions: NRS pain at rest, NRS pain during activities, EQ-5D-3L question 4, and OHS questions 1, 8, 10, and 12. For both NRS pain questions, previous studies reported thresholds of ≤3 for no or mild pain and &#62;3 for moderate to severe pain [<xref ref-type="bibr" rid="ref22">22</xref>,<xref ref-type="bibr" rid="ref23">23</xref>]. For the criterion of “using 2 crutches,” EQ-5D-3L question 1 and OHS question 6 were selected (step 2). The clinical expert panel assessed the selected questions, even the NRS pain question thresholds, as appropriate. The other thresholds were discussed and defined (step 3; <xref ref-type="table" rid="table1">Table 1</xref>).</p>
        <table-wrap position="float" id="table1">
          <label>Table 1</label>
          <caption>
            <p>Triage criteria, selected clinically relevant questions, and defined thresholds by the expert panels.</p>
          </caption>
          <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="30"/>
            <col width="280"/>
            <col width="0"/>
            <col width="470"/>
            <col width="0"/>
            <col width="220"/>
            <thead>
              <tr valign="bottom">
                <td colspan="3">Triage criterion and selected PROM<sup>a</sup> question</td>
                <td colspan="2">PROM question (score range)</td>
                <td>Defined threshold</td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td colspan="6">
                  <bold>Having moderate or severe pain</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>NRS<sup>b</sup> pain at rest</td>
                <td colspan="2">How much pain from your hip (surgery side) did you experience at rest in the last week? (0-10)</td>
                <td colspan="2">≥4</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>NRS pain during activity</td>
                <td colspan="2">How much pain from your hip (surgery side) did you experience during activity in the last week? (0-10)</td>
                <td colspan="2">≥4</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>EQ-5D-3L<sup>c</sup> question 4</td>
                <td colspan="2">Pain/discomfort (1-3)</td>
                <td colspan="2">≥3 (extreme pain)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>OHS<sup>d</sup> question 1</td>
                <td colspan="2">During the past 4 weeks...How would you describe the pain you usually had from your hip? (0-4)</td>
                <td colspan="2">≤1 (moderate or severe)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>OHS question 8</td>
                <td colspan="2">During the past 4 weeks...After a meal (sitting at a table), how painful has it been for you to stand up from a chair because of your hip? (0-4)</td>
                <td colspan="2">≤2 (moderate, very, unbearable)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>OHS question 10</td>
                <td colspan="2">During the past 4 weeks...Have you had any sudden, severe pain — “shooting,” “stabbing,” or “spasms” — from the affected hip? (0-4)</td>
                <td colspan="2">≤1 (most or every)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>OHS question 12</td>
                <td colspan="2">During the past 4 weeks...Have you been troubled by pain from your hip in bed at night? (0-4)</td>
                <td colspan="2">≤2 (3 or 4, 5 or 6, all)</td>
              </tr>
              <tr valign="top">
                <td colspan="6">
                  <bold>Using 2 crutches</bold>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>EQ-5D-3L question 1</td>
                <td colspan="2">Mobility (1-3)</td>
                <td colspan="2">≥3 (confined to bed)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>OHS question 6</td>
                <td colspan="2">During the past 4 weeks...For how long have you been able to walk before pain from your hip becomes severe (with or without a stick)? (0-4)</td>
                <td colspan="2">≤2 (5-15 minutes, around the house only, not at all)</td>
              </tr>
            </tbody>
          </table>
          <table-wrap-foot>
            <fn id="table1fn1">
              <p><sup>a</sup>PROM: patient-reported outcome measure.</p>
            </fn>
            <fn id="table1fn2">
              <p><sup>b</sup>NRS: numeric rating scale.</p>
            </fn>
            <fn id="table1fn3">
              <p><sup>c</sup>EQ-5D-3L: 3-level version of the EuroQol 5 dimensions.</p>
            </fn>
            <fn id="table1fn4">
              <p><sup>d</sup>OHS: Oxford Hip Score.</p>
            </fn>
          </table-wrap-foot>
        </table-wrap>
      </sec>
      <sec>
        <title>Clinimetric Qualities of Selected Questions or Triage Criteria Groups</title>
        <p>Response rates were statistically significantly equal between both training (n=746) and test (n=482) cohorts preoperatively (745/746, 99.9% versus 482/482, 100%; <italic>P</italic>=.99) and at 3 months (703/746, 94.2% versus 463/482, 96.1%; <italic>P</italic>=.24) and 12 months (693/746, 92.9% versus 457/482, 94.8%; <italic>P</italic>=.29) postoperatively. The training cohort consisted of significantly fewer patients than in the test cohort with an ASA I score (399/746, 53.5% versus 287/482, 59.5%; <italic>P</italic>=.04), lower Charnely scores (<italic>P</italic>=.048), higher preoperative HOOS-PS scores (median 46.1, IQR 37.7-55.9 versus median 46.1, IQR 33.9-55.9; <italic>P</italic>=.01), and lower preoperative OHS scores (median 24.0, IQR 19.0-29.0 versus median 25.0, IQR 19.0-31.0; <italic>P</italic>=.03; <xref ref-type="table" rid="table2">Table 2</xref>). The clinical expert panel assessed these differences as not clinically relevant to correct for.</p>
        <table-wrap position="float" id="table2">
          <label>Table 2</label>
          <caption>
            <p>Characteristics of training and test cohorts.</p>
          </caption>
          <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="30"/>
            <col width="30"/>
            <col width="300"/>
            <col width="0"/>
            <col width="240"/>
            <col width="0"/>
            <col width="200"/>
            <col width="0"/>
            <col width="200"/>
            <thead>
              <tr valign="top">
                <td colspan="4">Characteristics</td>
                <td colspan="2">Training cohort (n=746)</td>
                <td colspan="2">Test cohort (n=482)</td>
                <td><italic>P</italic> value</td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td colspan="4">
                  <bold>Response rate, n (%)</bold>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td colspan="2">Preoperative</td>
                <td colspan="2">745 (99.9)</td>
                <td colspan="2">482 (100)</td>
                <td colspan="2">.99</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td colspan="2">3 months postoperative</td>
                <td colspan="2">703 (94.2)</td>
                <td colspan="2">463 (96.1)</td>
                <td colspan="2">.24</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td colspan="2">12 months postoperative</td>
                <td colspan="2">693 (92.9)</td>
                <td colspan="2">457 (94.8)</td>
                <td colspan="2">.29</td>
              </tr>
              <tr valign="top">
                <td colspan="4">
                  <bold>Patient characteristics</bold>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td colspan="2">Age (years), median (IQR)</td>
                <td colspan="2">66.5 (61.0-72.0)</td>
                <td colspan="2">66.0 (60.0-72.0)</td>
                <td colspan="2">.73</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td colspan="2">Gender (male), n (%)</td>
                <td colspan="2">295 (39.5)</td>
                <td colspan="2">206 (42.7)</td>
                <td colspan="2">.27</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td colspan="2">BMI (kg/m<sup>2</sup>), median (IQR)</td>
                <td colspan="2">26.1 (24.1-28.4)</td>
                <td colspan="2">26.3 (24.1-28.5)</td>
                <td colspan="2">.48</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td colspan="2">ASA<sup>a</sup> score – I, n (%)</td>
                <td colspan="2">399 (53.5)</td>
                <td colspan="2">287 (59.5)</td>
                <td colspan="2">.04</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td colspan="2">
                  <bold>Charnley score:</bold>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td rowspan="5" colspan="2">.048</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>One hip affected by OA<sup>b</sup>, n (%)</td>
                <td colspan="2">163 (21.8)</td>
                <td colspan="2">108 (22.4)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>Both hips affected by OA, n (%)</td>
                <td colspan="2">309 (41.4)</td>
                <td colspan="2">196 (40.7)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>Contralateral hip OA, n (%)</td>
                <td colspan="2">163 (21.8)</td>
                <td colspan="2">82 (17.0)</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>Multiple joints affected by OA, n (%)</td>
                <td colspan="2">111 (14.9)</td>
                <td colspan="2">96 (19.9)</td>
              </tr>
              <tr valign="top">
                <td colspan="4">
                  <bold>Preoperative PROs<sup>c</sup>, median (IQR)</bold>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td colspan="2">
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
              </tr>
              <tr valign="top">
                <td/>
                <td colspan="2">NRS<sup>d</sup> pain at rest score</td>
                <td colspan="2">6.0 (4.0-7.0)</td>
                <td colspan="2">6.0 (3.8-7.0)</td>
                <td colspan="2">.18</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td colspan="2">NRS pain during activity score</td>
                <td colspan="2">8.0 (7.0-9.0)</td>
                <td colspan="2">8.0 (7.0-8.0)</td>
                <td colspan="2">.13</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td colspan="2">HOOS-PS<sup>e</sup> score</td>
                <td colspan="2">46.1 (37.7-55.9)</td>
                <td colspan="2">46.1 (33.9-55.9)</td>
                <td colspan="2">.01</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td colspan="2">EQ-5D descriptive system<sup>f</sup></td>
                <td colspan="2">0.693 (0.298-0.775)</td>
                <td colspan="2">0.693 (0.569-0.775)</td>
                <td colspan="2">.16</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td colspan="2">EQ VAS<sup>g</sup></td>
                <td colspan="2">76.0 (63.3-89.8)</td>
                <td colspan="2">77.0 (60.0-86.3)</td>
                <td colspan="2">.82</td>
              </tr>
              <tr valign="top">
                <td>
                  <break/>
                </td>
                <td colspan="2">OHS<sup>h</sup></td>
                <td colspan="2">24.0 (19.0-29.0)</td>
                <td colspan="2">25.0 (19.0-31.0)</td>
                <td colspan="2">.03</td>
              </tr>
            </tbody>
          </table>
          <table-wrap-foot>
            <fn id="table2fn1">
              <p><sup>a</sup>ASA: American Society of Anesthesiologists.</p>
            </fn>
            <fn id="table2fn2">
              <p><sup>b</sup>OA: osteoarthritis.</p>
            </fn>
            <fn id="table2fn3">
              <p><sup>c</sup>PROs: patient-reported outcomes.</p>
            </fn>
            <fn id="table2fn4">
              <p><sup>d</sup>NRS: numeric rating scale.</p>
            </fn>
            <fn id="table2fn5">
              <p><sup>e</sup>HOOS-PS: Hip disability and Osteoarthritis Outcome Score — Physical Function Shortform.</p>
            </fn>
            <fn id="table2fn6">
              <p><sup>f</sup>EQ-5D descriptive system: EuroQol 5 dimensions descriptive system.</p>
            </fn>
            <fn id="table2fn7">
              <p><sup>g</sup>EQ VAS: EuroQol visual analogue scale.</p>
            </fn>
            <fn id="table2fn8">
              <p><sup>h</sup>OHS: Oxford Hip Score.</p>
            </fn>
          </table-wrap-foot>
        </table-wrap>
        <p>Regarding the questions or triage criteria groups selected by the expert panels (<xref ref-type="table" rid="table1">Table 1</xref>), OHS question 10 showed no distribution. For floor effect, &#60;15% of patients scored the minimum score on all questions separately. All questions were significantly correlated with each other (<italic>P</italic>&#60;.001). Regarding correlations ≥0.7, NRS pain during activity correlated with NRS pain at rest (<italic>r</italic>=0.659, <italic>P</italic>&#60;.001) and OHS question 1 (<italic>r</italic>=–0.676, <italic>P</italic>&#60;.001; <xref ref-type="table" rid="table3">Table 3</xref>). Furthermore, all questions were shown to be responsive (<italic>P</italic>&#60;.001; <xref ref-type="table" rid="table4">Table 4</xref>). Regarding the PRO patient journey, patients with a worse score than the threshold also reported worse scores at 12 months than patients with a better score than the threshold. Only one patient with a better score than the threshold on EQ-5D-3L question 1 at 3 months had a 12-month score (<xref ref-type="table" rid="table5">Table 5</xref>). The other questions included ≥11 patients below or above the threshold. Regarding homogeneity, a Cronbach α of 0.818 was found for the triage criteria group “pain.” When one of the questions in this group was removed, the Cronbach α was maintained at above 0.7. The triage criteria group “crutches” scored a Cronbach α of 0.628. As there were 2 questions in this group, none of them could be removed to investigate the Cronbach α.</p>
        <table-wrap position="float" id="table3">
          <label>Table 3</label>
          <caption>
            <p>Distribution, floor effect, and correlation per selected patient-reported outcome measure (PROM) question.</p>
          </caption>
          <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="190"/>
            <col width="170"/>
            <col width="170"/>
            <col width="170"/>
            <col width="200"/>
            <col width="100"/>
            <thead>
              <tr valign="top">
                <td>PROM<sup>a</sup> question</td>
                <td>Distribution, median (IQR)</td>
                <td>Floor effect, n (%)</td>
                <td colspan="3">Correlations</td>
              </tr>
              <tr valign="bottom">
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>
                  <break/>
                </td>
                <td>Correlations (<italic>r</italic>)<sup>b</sup></td>
                <td>Correlated question</td>
                <td><italic>P</italic> value</td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td>NRS<sup>c</sup> pain at rest</td>
                <td>0 (0-1)</td>
                <td>3<sup>d</sup> (0.4)</td>
                <td>0.659</td>
                <td>NRS pain during activity</td>
                <td>&#60;.001</td>
              </tr>
              <tr valign="top">
                <td>NRS pain during activity</td>
                <td>2 (0-3)</td>
                <td>4<sup>d</sup> (0.6)</td>
                <td>0.659; –0.676</td>
                <td>NRS pain at rest; OHS<sup>e</sup> question 1</td>
                <td>Both &#60;.001</td>
              </tr>
              <tr valign="top">
                <td>EQ-5D-3L<sup>f</sup> question 4</td>
                <td>1 (1-2)</td>
                <td>13<sup>g</sup> (1.9)</td>
                <td>None</td>
                <td>N/A<sup>h</sup></td>
                <td>N/A</td>
              </tr>
              <tr valign="top">
                <td>OHS question 1</td>
                <td>3 (3-4)</td>
                <td>6<sup>g</sup> (0.9)</td>
                <td>–0.675</td>
                <td>NRS pain during activity</td>
                <td>&#60;.001</td>
              </tr>
              <tr valign="top">
                <td>OHS question 8</td>
                <td>3 (3-4)</td>
                <td>0<sup>g</sup> (0.0)</td>
                <td>None</td>
                <td>N/A</td>
                <td>N/A</td>
              </tr>
              <tr valign="top">
                <td>OHS question 10</td>
                <td>4 (4-4)</td>
                <td>2<sup>i</sup> (0.3)</td>
                <td>None</td>
                <td>N/A</td>
                <td>N/A</td>
              </tr>
              <tr valign="top">
                <td>OHS question 12</td>
                <td>4 (3-4)</td>
                <td>32<sup>i</sup> (4.6)</td>
                <td>None</td>
                <td>N/A</td>
                <td>N/A</td>
              </tr>
              <tr valign="top">
                <td>EQ-5D-3L question 1</td>
                <td>1 (1-2)</td>
                <td>2<sup>i</sup> (0.3)</td>
                <td>None</td>
                <td>N/A</td>
                <td>N/A</td>
              </tr>
              <tr valign="top">
                <td>OHS question 6</td>
                <td>4 (3-4)</td>
                <td>3<sup>j</sup> (0.4)</td>
                <td>None</td>
                <td>N/A</td>
                <td>N/A</td>
              </tr>
            </tbody>
          </table>
          <table-wrap-foot>
            <fn id="table3fn1">
              <p><sup>a</sup>PROM: patient-reported outcome measure.</p>
            </fn>
            <fn id="table3fn2">
              <p><sup>b</sup>Statistically significant correlations &#62;0.6 or &#60;–0.6 are presented.</p>
            </fn>
            <fn id="table3fn3">
              <p><sup>c</sup>NRS: numeric rating scale.</p>
            </fn>
            <fn id="table3fn4">
              <p><sup>d</sup>n=703.</p>
            </fn>
            <fn id="table3fn5">
              <p><sup>e</sup>OHS: Oxford Hip Score.</p>
            </fn>
            <fn id="table3fn6">
              <p><sup>f</sup>EQ-5D-3L: 3-level version of the EuroQol 5 dimensions.</p>
            </fn>
            <fn id="table3fn7">
              <p><sup>g</sup>n=693.</p>
            </fn>
            <fn id="table3fn8">
              <p><sup>h</sup>N/A: not applicable.</p>
            </fn>
            <fn id="table3fn9">
              <p><sup>i</sup>n=694.</p>
            </fn>
            <fn id="table3fn10">
              <p><sup>j</sup>n=690.</p>
            </fn>
          </table-wrap-foot>
        </table-wrap>
        <table-wrap position="float" id="table4">
          <label>Table 4</label>
          <caption>
            <p>Responsiveness for each patient-reported outcome measure (PROM) question.</p>
          </caption>
          <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="280"/>
            <col width="220"/>
            <col width="300"/>
            <col width="200"/>
            <thead>
              <tr valign="top">
                <td>PROM question</td>
                <td>Preoperative, median (IQR)</td>
                <td>3 months postoperative, median (IQR)</td>
                <td><italic>P</italic> value</td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td>NRS<sup>a</sup> pain at rest</td>
                <td>6 (4-7)</td>
                <td>0 (0-1)</td>
                <td>&#60;.001</td>
              </tr>
              <tr valign="top">
                <td>NRS pain during activity</td>
                <td>8 (7-9)</td>
                <td>2 (0-3)</td>
                <td>&#60;.001</td>
              </tr>
              <tr valign="top">
                <td>EQ-5D-3L<sup>b</sup> question 4</td>
                <td>2 (2-3)</td>
                <td>1 (1-2)</td>
                <td>&#60;.001</td>
              </tr>
              <tr valign="top">
                <td>OHS<sup>c</sup> question 1</td>
                <td>1 (0-1)</td>
                <td>3 (3-4)</td>
                <td>&#60;.001</td>
              </tr>
              <tr valign="top">
                <td>OHS question 8</td>
                <td>2 (2-3)</td>
                <td>3 (3-4)</td>
                <td>&#60;.001</td>
              </tr>
              <tr valign="top">
                <td>OHS question 10</td>
                <td>2 (1-3)</td>
                <td>4 (4-4)</td>
                <td>&#60;.001</td>
              </tr>
              <tr valign="top">
                <td>OHS question 12</td>
                <td>2 (0-3)</td>
                <td>4 (3-4)</td>
                <td>&#60;.001</td>
              </tr>
              <tr valign="top">
                <td>EQ-5D-3L question 1</td>
                <td>2 (2-2)</td>
                <td>1 (1-2)</td>
                <td>&#60;.001</td>
              </tr>
              <tr valign="top">
                <td>OHS question 6</td>
                <td>2 (2-3)</td>
                <td>4 (3-4)</td>
                <td>&#60;.001</td>
              </tr>
            </tbody>
          </table>
          <table-wrap-foot>
            <fn id="table4fn1">
              <p><sup>a</sup>NRS: numeric rating scale.</p>
            </fn>
            <fn id="table4fn2">
              <p><sup>b</sup>EQ-5D-3L: 3-level version of the EuroQol 5 dimensions.</p>
            </fn>
            <fn id="table4fn3">
              <p><sup>c</sup>OHS: Oxford Hip Score.</p>
            </fn>
          </table-wrap-foot>
        </table-wrap>
        <table-wrap position="float" id="table5">
          <label>Table 5</label>
          <caption>
            <p>Patient journey per patient-reported outcome measure (PROM) question.</p>
          </caption>
          <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="180"/>
            <col width="140"/>
            <col width="330"/>
            <col width="350"/>
            <thead>
              <tr valign="top">
                <td>PROM question</td>
                <td>Defined threshold</td>
                <td>12-month score of patients with a score below the threshold at 3 months, median (IQR)</td>
                <td>12-month score of patients with a score above the threshold at 3 months, median (IQR)</td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td>NRS<sup>a</sup> pain at rest</td>
                <td>≥4</td>
                <td>0 (0-1)</td>
                <td>2 (0-5)</td>
              </tr>
              <tr valign="top">
                <td>NRS pain during activity</td>
                <td>≥4</td>
                <td>0 (0-1)</td>
                <td>2 (0-4)</td>
              </tr>
              <tr valign="top">
                <td>EQ-5D-3L<sup>b</sup> question 4</td>
                <td>≥3</td>
                <td>1 (1-2)</td>
                <td>2 (1.5-2)</td>
              </tr>
              <tr valign="top">
                <td>OHS<sup>c</sup> question 1</td>
                <td>≤1</td>
                <td>3 (2-4)</td>
                <td>4 (3-4)</td>
              </tr>
              <tr valign="top">
                <td>OHS question 8</td>
                <td>≤2</td>
                <td>3 (3-4)</td>
                <td>4 (4-4)</td>
              </tr>
              <tr valign="top">
                <td>OHS question 10</td>
                <td>≤1</td>
                <td>4 (2.5-3)</td>
                <td>4 (4-4)</td>
              </tr>
              <tr valign="top">
                <td>OHS question 12</td>
                <td>≤2</td>
                <td>3 (1.5-4)</td>
                <td>4 (4-4)</td>
              </tr>
              <tr valign="top">
                <td>EQ-5D-3L question 1</td>
                <td>≥3</td>
                <td>1 (1-2)</td>
                <td>1 (1-1)<sup>d</sup></td>
              </tr>
              <tr valign="top">
                <td>OHS question 6</td>
                <td>≤2</td>
                <td>3 (2-4)</td>
                <td>4 (4-4)</td>
              </tr>
            </tbody>
          </table>
          <table-wrap-foot>
            <fn id="table5fn1">
              <p><sup>a</sup>NRS: numeric rating scale.</p>
            </fn>
            <fn id="table5fn2">
              <p><sup>b</sup>EQ-5D-3L: 3-level version of the EuroQol 5 dimensions.</p>
            </fn>
            <fn id="table5fn3">
              <p><sup>c</sup>OHS: Oxford Hip Score.</p>
            </fn>
            <fn id="table5fn4">
              <p><sup>d</sup>n=1.</p>
            </fn>
          </table-wrap-foot>
        </table-wrap>
        <p>Based on the clinimetric qualities of selected questions or triage criteria groups, NRS pain at rest, OHS question 1, and OHS question 10 were removed from the triage tool. The final triage tool consisted of NRS pain during activity; EQ-5D-3L questions 1 and 4; and OHS questions 6, 8, and 12.</p>
      </sec>
      <sec>
        <title>Evaluation of the Final Triage Tool</title>
        <p>The final triage tool resulted in 201 (201/703, 28.6%) patients in the training cohort needing a hospital consultation, which was statistically equal to the 150 (150/463, 32.4%) patients in the test cohort who needed a hospital consultation (<italic>P</italic>=.19).</p>
      </sec>
    </sec>
    <sec sec-type="discussion">
      <title>Discussion</title>
      <p>This study aimed to develop a tool based on PROs collected using an existing PROM infrastructure to triage THA patients to hospital or video consultation 6 weeks postoperatively. As the main finding, a triage tool based on PROM questions measuring moderate or severe pain and whether the patient used 2 crutches was developed. The included questions were NRS pain during activity; EQ-5D-3L questions 1 and 4; and OHS questions 6, 8, and 12. Applying the final triage tool in both the training and test cohorts resulted in the same outcome: Around 70% of the patients could safely have a video consultation, and 30% needed to have a hospital consultation 6 weeks postoperatively. Therefore, this PRO triage tool is a promising instrument to select patients for video consultation while using an existing PROM infrastructure. The next step is to further investigate this triage tool in daily practice.</p>
      <p>This study showed that 70% of the hospital consultations for THA patients 6 weeks postoperatively could safely be done by video. It was hypothesized that 10% of the THA patients would need a hospital consultation. First, the result that 30% of patients needed a hospital consultation could be explained by the focus of the clinical expert panel. As the experts’ beginning point was seeing all patients during a hospital consultation (100%), by developing the triage tool, they desired to see all patients who potentially needed a physical examination or other examination, such as an X-ray, during a hospital consultation. Furthermore, they desired to prevent obtaining more consultations by needing to schedule a hospital consultation after a video consultation. Both implicitly resulted in more liberal criteria for a hospital consultation leading to more patients triaged to a hospital consultation. Second, it could be that specific questions are missing from the triage tool. It was hypothesized that, after an investigation of the triage tool in daily practice, the criteria for the triage tool could be improved, achieving the right health care for each patient and a further reduction in hospital consultations. It would be interesting to investigate how many additional hospital consultations would be needed if the tool triages to video consultation and which PROs are different for patients with an additional hospital consultation.</p>
      <p>It is essential to understand that the PRO triage tool is not a tool on its own, but it is the first step in the selection of patients who need a hospital consultation and those who can have a video consultation instead. PROs and clinical judgment produce complementary data and when combined, provide a more accurate description of the patients’ symptoms [<xref ref-type="bibr" rid="ref24">24</xref>]. Therefore, using the current PRO triage tool, clinicians should have the ability to change the outcome of the tool. To further develop the triage tool, it would be interesting to investigate how many times clinicians decide to change the outcome and which PROs are different for the patients whose clinicians decide to change the outcome. Furthermore, it would be interesting to take the patient’s preference into account.</p>
      <p>Previous studies reported that patients rate their video consultations as excellent or very good (92%-95%) [<xref ref-type="bibr" rid="ref25">25</xref>,<xref ref-type="bibr" rid="ref26">26</xref>]. The patient no-show rate has been reported at 2.8%, and their mean estimated saved travel time is 30 minutes [<xref ref-type="bibr" rid="ref25">25</xref>]. Furthermore, 82% would recommend video consultation to family and friends [<xref ref-type="bibr" rid="ref26">26</xref>]. Almost all clinicians rate their video consultation experience as very good or excellent (92%). They are comfortable with executing this type of consultation after 1 to 4 sessions (69%) [<xref ref-type="bibr" rid="ref25">25</xref>]. Therefore, video consultation is a serious alternative for hospital consultation. Numbers could be improved when appropriate patients for video consultation are selected, which makes the developed PRO triage tool a promising instrument.</p>
      <p>As a first strength of this study, to the authors’ knowledge, this is the first study in which a tool to triage patients to hospital or video consultation was developed. Second, high response rates preoperatively and even postoperatively (above 90%) were achieved, resulting in a representative cohort to execute this study and to generalize the results to the total THA population. A third strength is the application of the training and test cohorts to provide an unbiased evaluation of the final tool.</p>
      <p>As a limitation of this study, the triage tool was not investigated in a prospective cohort, and aspects of reliability, validity, sensitivity, and specificity of the triage tool were not investigated yet. Furthermore, 3-month PROs were used instead of 6-week PROs, as, although based on previous studies, the assumption was made that there is limited clinically relevant difference between PROs at 6 weeks and at 3 months postoperatively [<xref ref-type="bibr" rid="ref11">11</xref>,<xref ref-type="bibr" rid="ref12">12</xref>]. Future research should be executed in a prospective cohort, and aspects of reliability, validity, sensitivity, and specificity need to be investigated to further develop the THA PRO triage tool. The triage tool could be improved by investigating which PROs are different for patients with additional hospital consultations after being triaged to video consultation or for patients whose clinician decided to change the outcome of the triage tool. After improving the triage tool, it would be interesting to investigate if and which of the patients triaged to video consultation may not require a consultation at all.</p>
      <p>In conclusion, a THA PRO triage tool based on moderate or severe pain and using 2 crutches was developed. Around 70% of THA patients could safely have a video consultation, and 30% of patients needed a hospital consultation 6 weeks postoperatively. This tool is promising for selecting patients for video consultation while using an existing PROM infrastructure.</p>
    </sec>
  </body>
  <back>
    <app-group/>
    <glossary>
      <title>Abbreviations</title>
      <def-list>
        <def-item>
          <term id="abb1">ASA</term>
          <def>
            <p>American Society of Anesthesiologists</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb2">EQ VAS</term>
          <def>
            <p>EuroQol visual analogue scale</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb3">EQ-5D descriptive system</term>
          <def>
            <p>EuroQol 5 dimensions descriptive system</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb4">EQ-5D-3L</term>
          <def>
            <p>3-level version of the EuroQol 5 dimensions</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb5">HOOS-PS</term>
          <def>
            <p>Hip disability and Osteoarthritis Outcome Score – Physical Function Shortform</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb6">NRS</term>
          <def>
            <p>numeric rating scale</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb7">OHS</term>
          <def>
            <p>Oxford Hip Score</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb8">PROM(s)</term>
          <def>
            <p>patient-reported outcome measure(s)</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb9">PRO(s)</term>
          <def>
            <p>patient-reported outcome(s)</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb10">THA</term>
          <def>
            <p>total hip arthroplasty</p>
          </def>
        </def-item>
      </def-list>
    </glossary>
    <ack>
      <p>We would like to thank Klaartje van Diepen-Pijnappels and Maud Peters for their consistent data collection and kindness helping all patients who had questions, all patients for completing their PROMs, and the orthopedic surgeons for participating in the clinical expert panel.</p>
      <p>This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sector.</p>
    </ack>
    <fn-group>
      <fn fn-type="con">
        <p>YP was responsible for designing the study, data collection, statistical analysis, and study coordination. All authors were involved in drafting and revising the manuscript and approved the final version of the manuscript.</p>
      </fn>
      <fn fn-type="conflict">
        <p>PP was a paid employee of ZimmerBiomet, and WW is a consultant for ZimmerBiomet, which have nonfinancial associations that may be relevant to the submitted manuscript. BWS receives a grant for providing an educational Stryker course on the Exeter prosthesis and is a board member of the European Hip Society, which has nonfinancial associations that may be relevant to the submitted manuscript. The other authors declare that they have no conflict of interest.</p>
      </fn>
    </fn-group>
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